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 Allergy Advisor Digest - July 2016
Editor: Dr. Harris A. Steinman

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This is a monthly digest of interesting information that is being added to Allergy Advisor. While we add a great deal of information every month, here we highlight some of the more interesting articles.
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Read Heavy metal and tattoo: an allergy and legislative problem.
Read Patients with breakthrough reactions to iodinated contrast media have low incidence of positive skin tests.
Read Domestic dog exposure at birth reduces the incidence of atopic dermatitis.
Read Prevalence of food sensitization and probable food allergy among adults in India
Read House Dust Mite-Derived Chitin Enhances Th2 Cell Response to Inhaled Allergens.
Read Characteristics of Anaphylaxis in 907 Chinese Patients Referred to a Tertiary Allergy Center
Read Detection of allergen specific antibodies from nasal secretion of allergic rhinitis patients.
Read No concentration decrease of house dust mite allergens with rising altitude in alpine regions.
Read Crotoxin: a novel allergen to occupational anaphylaxis.
Read Comparison between specific IgE levels and skin prick test results of local and imported American cockroach, dog, cat, dust mites and mold allergen extracts.
Read Immediate drug hypersensitivity.
Read Allergen component analysis as a tool in the diagnosis of occupational allergy.
Read Intrasubject variability in Total IgE levels in patients with moderate to severe persistent allergic asthma over 1 year.
Read House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs.

Abstracts shared in July 2016 Advisor Digest Newsletter

Read An unexpected cause of anaphylaxis: potato.
Read Food allergy in breastfeeding babies. Hidden allergens in human milk.
Read Asymptomatic LTP sensitisation is common in plant-food allergic children from the Northeast of Spain.
Read A case of black garlic-induced pneumonia as an adverse reaction.
Read Anaphylaxis caused by casein used in artificially marbled beef: A case report.
Read Occupational allergic respiratory disease due to royal jelly (Propolis).
Read IgE-associated food allergy alters the presentation of pediatric eosinophilic esophagitis.
Read How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results.
Read Sensitization to food additives in patients with allergy: a study based on skin test and open oral challenge.

Allergy and Intolerance Abstracts
Heavy metal and tattoo: an allergy and legislative problem.
An interesting clinical case of a 23 years old man presented with a 2-week history of pruritus, erythema and papules on legs, arms and trunk. These lesions developed 2 months after tattooing. It showed positive patch test reaction to Copper and Disperse Blu.

Heavy metal and tattoo: an allergy and legislative problem.  
Tammaro A, Cortesi G, Pigliacelli F, Parisella FR, Persechino F, De MG, Persechino S.
Eur Ann Allergy Clin Immunol 2016 Jul;48(4):153-155

Click to view abstract

Index
Allergy and Intolerance Abstracts
Patients with breakthrough reactions to iodinated contrast media have low incidence of positive skin tests.
The term 'breakthrough reactions' designates repeated hypersensitivity reactions to iodinated contrast media (ICM) despite premedication with glucocorticoids and antihistamines. We aimed to retrospectively evaluate the rate of positive skin test (STs) in our cohort of patients with previous breakthrough reactions to different ICMs. A series of 35 patients, who experienced at least one breakthrough reaction to ICM and who underwent STs within 6 months from the reaction were studied, and results were compared to a control group of patients with a first hypersensitivity reaction occurred without premedication. Of the 35 patients with prior breakthrough reactions, 57% had an immediate reaction (IR) and 43% had a non-immediate reaction (NIR). Patients who experienced the first hypersensitivity IR or NIR, later had one or more breakthrough IR or NIR, respectively. Overall, 29% (10/35) of patients with prior breakthrough reactions resulted positive to STs compared to 57% (16/28) of the control group (p < 0.05). No significant difference in allergy history, age, sex, other clinical / demographic features nor chronic use of ACE-inhibitor, beta-blockers or NSAIDs was observed.

Patients with breakthrough reactions to iodinated contrast media have low incidence of positive skin tests.  
Berti A, la-Torre E, Yacoub M, Tombetti E, Canti V, Sabbadini MG, Colombo G.
Eur Ann Allergy Clin Immunol 2016 Jul;48(4):137-144

Click to view abstract

Index
Allergy and Intolerance Abstracts
Domestic dog exposure at birth reduces the incidence of atopic dermatitis.
Neonatal domestic dog exposure was associated with a strongly reduced risk of atopic dermatitis in two independent birth cohorts and in a dose-dependent manner. While the mechanisms involved are unclear, our findings raise the question whether in utero exposures may affect the risk of atopic dermatitis and emphasize the importance of the early environment for disease trajectory.

Domestic dog exposure at birth reduces the incidence of atopic dermatitis.  
Thorsteinsdottir S, Thyssen JP, Stokholm J, Vissing NH, Waage J, Bisgaard H.
Allergy 2016 Jul 6;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Prevalence of food sensitization and probable food allergy among adults in India
This study reports the prevalence of sensitization and probable food allergy to 24 common foods among adults from general population in Karnataka, South India. The study was conducted in two stages: a screening study and a case-control study. A total of 11 791 adults in age group 20-54 were randomly sampled from general population in South India and answered a screening questionnaire. A total of 588 subjects (236 cases and 352 controls) participated in the case-control study involving a detailed questionnaire and specific IgE estimation for 24 common foods. A high level of sensitization (26.5%) was observed for most of the foods in the general population, higher than that observed among adults in Europe, except for those foods that cross-react with birch pollen. Most of the sensitization was observed in subjects who had total IgE above the median IgE level. A high level of cross-reactivity was observed among different pollens and foods and among foods. The prevalence of probable food allergy (self-reports of adverse symptoms after the consumption of food and specific IgE to the same food) was 1.2%, which was mainly accounted for cow's milk (0.5%) and apple (0.5%).

Prevalence of food sensitization and probable food allergy among adults in India: the EuroPrevall INCO study.  
Mahesh PA, Wong GW, Ogorodova L, Potts J, Leung TF, Fedorova O, Holla AD, Fernandez-Rivas M, Clare Mills EN, Kummeling I, Versteeg SA, van RR, Yazdanbakhsh M, Burney P.
Allergy 2016 Jul;71(7):1010-1019

Click to view abstract

Index
Allergy and Intolerance Abstracts
House Dust Mite-Derived Chitin Enhances Th2 Cell Response to Inhaled Allergens.
This data suggest that HDM-derived chitin may enhance airway hypersensitivity to inhaled allergens, via the TLR2-dependent pathway, and that chitin-induced TNF-alpha can be a key mediator in the development of Th2 cell response to inhaled allergens.

House Dust Mite-Derived Chitin Enhances Th2 Cell Response to Inhaled Allergens, Mainly via a TNF-alpha-Dependent Pathway.  
Choi JP, Lee SM, Choi HI, Kim MH, Jeon SG, Jang MH, Jee YK, Yang S, Cho YJ, Kim YK.
Allergy Asthma Immunol Res 2016 Jul;8(4):362-374

Click to view abstract

Index
Allergy and Intolerance Abstracts
Characteristics of Anaphylaxis in 907 Chinese Patients Referred to a Tertiary Allergy Center
Outpatients diagnosed with 'anaphylaxis' or 'severe allergic reactions' in the Department of Allergy, Peking Union Medical College Hospital from January 1, 2000 to June 30, 2014 were analyzed retrospectively. A total of 1,952 episodes of anaphylaxis in 907 patients were analyzed (78% were adults and 22% were children). Foods are the most common cause (77%), followed by idiopathic etiologies (15%), medications (7%) and insects (0.6%). In food-induced anaphylaxis, 62% (13/21) of anaphylaxis in infants and young children (0-3 years of age) were triggered by milk, 59% (36/61) of anaphylaxis in children (4-9 years of age) were triggered by fruits/vegetables, while wheat was the cause of anaphylaxis in 20% (56/282) of teenagers (10-17 years of age) and 42% (429/1,016) in adults (18-50 years of age). Mugwort pollen sensitization was common in patients with anaphylaxis induced by spices, fruits/vegetables, legume/peanuts, and tree nuts/seeds, with the prevalence rates of 75%, 67%, 61%, and 51%, respectively. Thirty-six percent of drug-induced anaphylaxis was attributed to traditional Chinese Medicine. For patients receiving emergency care, only 25% of patients received epinephrine.

Characteristics of Anaphylaxis in 907 Chinese Patients Referred to a Tertiary Allergy Center: A Retrospective Study of 1,952 Episodes.  
Jiang N, Yin J, Wen L, Li H.
Allergy Asthma Immunol Res 2016 Jul;8(4):353-361

Click to view abstract

Index
Allergy and Intolerance Abstracts
Detection of allergen specific antibodies from nasal secretion of allergic rhinitis patients.
The aims of this study were to confirm the presence of locally produced antibodies to D. farinae in nasal secretions between nasal provocation test (NPT)-positive and -negative groups of AR patients. Sixty AR patients sensitive to house dust mites confirmed by skin prick test or serum specific IgE to D. farinae underwent NPT for D. farinae. High levels of total IgE, specific IgE, specific IgA, and secretory IgA to D. farinae, as well as inflammatory mediators, such as ECP, IL-8, VEGF and tryptase, were detected in nasal secretions, although the differences were not statistically significant between the NPT-positive and NPT-negative groups. Levels of all immunoglobulins measured in this study significantly correlated with ECP, IL-8, and VEGF (P<0.05), but not with tryptase (P>0.05). IL-33 and IL-25 were also detected, and IL-25 level significantly correlated with IL-8 (r=0.625, P<0.001).

Detection of allergen specific antibodies from nasal secretion of allergic rhinitis patients.  
Kim JH, Yoon MG, Seo DH, Kim BS, Ban GY, Ye YM, Shin YS, Park HS.
Allergy Asthma Immunol Res 2016 Jul;8(4):329-337

Click to view abstract

Index
Allergy and Intolerance Abstracts
No concentration decrease of house dust mite allergens with rising altitude in alpine regions.
Several studies over the past 4 decades have indicated a significant reduction in house dust mite (HDM) and HDM allergen concentration in areas higher than 1,500 m above sea level. These have served as basis of allergen avoidance therapies for HDM allergy and asthma. However, modern construction techniques used in the insulation, heating, and glazing of buildings as well as global warming have changed the environmental parameters for HDM living conditions. The present study revisits the paradigm of decreasing HDM allergen concentrations with increasing altitude in the alpine region of Germany and Austria. A total of 122 dust samples from different abodes (hotels, privates and mountain huts) at different altitudes (400-2,600 m) were taken, and concentrations of HDM allergens were analyzed. Humidity and temperature conditions, and numerous indoor environmental parameters such as fine dust, type of flooring, age of building, and frequency of cleaning were determined.

In contrast to the widespread view of the relationship between altitude and HDM allergen concentrations, clinically relevant concentrations of HDM allergens could be detected in high-lying alpine regions in Austria and Germany. These results indicate that improvement in conditions of asthmatic patients sensitized against HDMs during a stay at high altitude can no longer be ascribed to decreased levels of HDM allergens, instead, other mechanisms may trigger the beneficial effect

No concentration decrease of house dust mite allergens with rising altitude in alpine regions.  
Grafetstatter C, Prossegger J, Braunschmid H, Sanovic R, Hahne P, Pichler C, Thalhamer J, Hartl A.
Allergy Asthma Immunol Res 2016 Jul;8(4):312-318

Click to view abstract

Index
Allergy and Intolerance Abstracts
Crotoxin: a novel allergen to occupational anaphylaxis.
A 23-year-old, white, female student worked with snake venom for 4 years at a research laboratory. Her exposure to rattlesnake venom occurred during pro- cedures in the Laboratory of Venom Animals. She began presenting with allergic reactions characterized by sneezing, itchy skin, and nasoconjunctival hyperemia soon after manipulating lyophilized rattlesnake venom. These symptoms resolved spontaneously 10 to 15 minutes after the patient would leave the laboratory. She experienced an episode including in addition eyelid edema, wheezing, dyspnea, cough, hoarseness, and dysphagia, displaying a clinical picture of anaphylaxis. An ImmunoCAP ?uoroimmunoassay system against C d terri?cus snake venom was developed exclusively for this study by MIAB, Uppsala, Sweden, to quantify the speci?c IgE levels; the result was 0.7 kU/L. Immunodetection assays revealed a single immunoreactive protein from total venom: a 23 kDa. The allergen was identi?ed as crotoxin.

Crotoxin: a novel allergen to occupational anaphylaxis.  
de Pontes LG, Cavassan NR, Creste CF, Junior AL, Arcuri HA, Ferreira RS, Barraviera B, Gagete E, Dos Santos LD.
Ann Allergy Asthma Immunol 2016 Apr 6;

Index
Allergy and Intolerance Abstracts
Comparison between specific IgE levels and skin prick test results of local and imported American cockroach, dog, cat, dust mites and mold allergen extracts.
This Thai study compared SPT results of local and imported allergen extracts and sIgE levels in response to the American cockroach, dog, cat, Dermatophagoides pteronyssinus (Dp), Dermatophagoides farinae (Df) and Cladosporium spp. allergens. The agreement between SPT results from each local and imported allergen extract was statistically significant, and the level of agreement for dog allergens was very good (kappa >0.8). All patients with a positive SPT in response to imported Dp allergen extract had positive SPT in response to local Dp allergen extract. Mean wheal diameter of each allergen in both groups showed significant correlation with sIgE levels. The correlation coefficient (CC) for cat allergens showed a very good-to-excellent relationship (CC>0.75). When compared with sIgE levels, SPT results for imported and local allergen extracts showed comparable sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio (LR)+ and LR-.

Comparison between specific IgE levels and skin prick test results of local and imported American cockroach, dog, cat, dust mites and mold allergen extracts.  
Visitsunthorn N, Sripramong C, Bunnag C, Jirapongsananuruk O.
Asian Pac J Allergy Immunol 2016 Jun 30;

Click to view abstract

Index
Allergy and Intolerance Abstracts
Immediate drug hypersensitivity.
Drug allergy affects a large percentage of the general population. A listed drug allergy can also have broad implications for many aspects of patient care. Here, we will review recent advances in the arena of drug allergies with a focus on antibiotics, monoclonals, NSAIDs, and chemotherapeutics

Immediate drug hypersensitivity.  
Wickner PG, Hong D.
Curr Allergy Asthma Rep 2016 Jul;16(7):49

Click to view abstract

Index
Allergy and Intolerance Abstracts
Allergen component analysis as a tool in the diagnosis of occupational allergy.
More than 400 agents are identified as sensitizers of occupational asthma, but only very few are characterized on the molecular level and available for routine diagnosis. Baker’s asthma is one of the most frequently occurring forms of occupational asthma caused by workplace-related inhalation of cereal flour mainly wheat. Wheat sensitization profiles of bakers show great interindividual variability and no wheat allergen could be classified as the major allergen. Component-resolved diagnosis is a useful tool for diagnosing natural rubber latex (NRL) allergy. In cases with unexpected high-latex IgE but without clinical symptoms application of crossreactive carbohydrate determinants are helpful to clarify the cause of IgE binding. Latex is an excellent model for component-resolved diagnosis and demonstrates well how to improve the diagnosis by using single allergens. For diagnosis of baker’s asthma, a whole wheat extract is still the best option for specific IgE determination, but single wheat allergens might help to discriminate between wheatinduced food allergy, grass-pollen allergy, and baker’s asthma.

Allergen component analysis as a tool in the diagnosis of occupational allergy.  
Raulf M.
Curr Opin Allergy Clin Immunol 2016 Apr;16(2):93-100

Index
Allergy and Intolerance Abstracts
Intrasubject variability in Total IgE levels in patients with moderate to severe persistent allergic asthma over 1 year.
Longitudinal variability in serum IgE levels has not been prospectively studied in people with moderate to severe allergic asthma. This study investigated change in serum IgE concentrations in 17 patients over 1 year, and its relationship with lung function, asthma control, asthma pharmacotherapy, allergy season, asthma exacerbations, body mass index, and demographic factors. For consecutive visits every 2 months, the mean percent change in serum IgE level was 23 +/- 3 (P < .001). Serum IgE concentrations exhibit variability over time among individuals with moderate to severe persistent allergic asthma.

Intrasubject variability in Total IgE levels in patients with moderate to severe persistent allergic asthma over 1 year.  
Hatipoglu U, Subramanian A, Campbell T, Rice R, Mummadi S, Hu B, Lang DM.
J Allergy Clin Immunol Pract 2016 Jul;4(4):691-696

Click to view abstract

Index
Allergy and Intolerance Abstracts
House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs.
Asthma is related to airway inflammation and oxidative stress. High levels of reactive oxygen and nitrogen species can induce cytotoxic DNA damage. Nevertheless, little is known about the possible role of allergen-induced DNA damage and DNA repair as modulators of asthma-associated pathology. This study sought to study DNA damage and DNA damage responses induced by house dust mite (HDM) in vivo and in vitro.

The study concludes that this work calls attention to reactive oxygen and nitrogen species and HDM-induced cytotoxicity and to a potential role for DNA repair as a modulator of asthma-associated pathophysiology.

House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs.  
Chan TK, Loh XY, Peh HY, Tan WN, Tan WS, Li N, Tay IJ, Wong WS, Engelward BP.
J Allergy Clin Immunol 2016 Jul;138(1):84-96

Click to view abstract

Index

Allergen-, Food allergy-, Intolerance-related articles

Heavy metal and tattoo: an allergy and legislative problem.  
Tammaro A, Cortesi G, Pigliacelli F, Parisella FR, Persechino F, De MG, Persechino S.
Eur Ann Allergy Clin Immunol 2016 Jul;48(4):153-155
Click to view abstract

An unexpected cause of anaphylaxis: potato.  
Eke GH, Uytun S, Murat SU, Altuner TY.
Eur Ann Allergy Clin Immunol 2016 Jul;48(4):149-152
Click to view abstract

Patients with breakthrough reactions to iodinated contrast media have low incidence of positive skin tests.  
Berti A, la-Torre E, Yacoub M, Tombetti E, Canti V, Sabbadini MG, Colombo G.
Eur Ann Allergy Clin Immunol 2016 Jul;48(4):137-144
Click to view abstract

Food allergy in breastfeeding babies. Hidden allergens in human milk.  
Martin-Munoz MF, Pineda F, Garcia PG, Guillen D, Rivero D, Belver T, Quirce S.
Eur Ann Allergy Clin Immunol 2016 Jul;48(4):123-128
Click to view abstract

Asymptomatic LTP sensitisation is common in plant-food allergic children from the Northeast of Spain.  
Pascal M, Vazquez-Ortiz M, Folque MM, Jimenez-Feijoo R, Lozano J, Dominguez O, Piquer-Gibert M, Giner MT, Alvaro M, as da CM, Garcia-Paba B, Machinena A, Alsina L, Yague J, Plaza-Martin AM.
Allergol Immunopathol (Madr ) 2016 Jul;44(4):351-358
Click to view abstract

A case of black garlic-induced pneumonia as an adverse reaction.  
Suzuki Y, Saito J, Misa K, Fukuhara N, Fukuhara A, Munakata M.
Allergol Int 2016 Jul;65(3):353-355

Anaphylaxis caused by casein used in artificially marbled beef: A case report.  
Narabayashi S, Okafuji I, Tanaka Y, Tsuruta S, Takamatsu N.
Allergol Int 2016 Jul;65(3):341-342

Development of a prediction model of severe reaction in boiled egg challenges.  
Sugiura S, Matsui T, Nakagawa T, Sasaki K, Nakata J, Kando N, Ito K.
Allergol Int 2016 Jul;65(3):293-299
Click to view abstract

Domestic dog exposure at birth reduces the incidence of atopic dermatitis.  
Thorsteinsdottir S, Thyssen JP, Stokholm J, Vissing NH, Waage J, Bisgaard H.
Allergy 2016 Jul 6;
Click to view abstract

Prevalence of food sensitization and probable food allergy among adults in India: the EuroPrevall INCO study.  
Mahesh PA, Wong GW, Ogorodova L, Potts J, Leung TF, Fedorova O, Holla AD, Fernandez-Rivas M, Clare Mills EN, Kummeling I, Versteeg SA, van RR, Yazdanbakhsh M, Burney P.
Allergy 2016 Jul;71(7):1010-1019
Click to view abstract

House Dust Mite-Derived Chitin Enhances Th2 Cell Response to Inhaled Allergens, Mainly via a TNF-alpha-Dependent Pathway.  
Choi JP, Lee SM, Choi HI, Kim MH, Jeon SG, Jang MH, Jee YK, Yang S, Cho YJ, Kim YK.
Allergy Asthma Immunol Res 2016 Jul;8(4):362-374
Click to view abstract

Characteristics of Anaphylaxis in 907 Chinese Patients Referred to a Tertiary Allergy Center: A Retrospective Study of 1,952 Episodes.  
Jiang N, Yin J, Wen L, Li H.
Allergy Asthma Immunol Res 2016 Jul;8(4):353-361
Click to view abstract

Response to Nonallergenic Irritants in Children With Allergic and Nonallergic Rhinitis.  
Baek JH, Cho E, Kim MA, Lee SW, Kang YS, Sheen YH, Jee HM, Jung YH, Han MY.
Allergy Asthma Immunol Res 2016 Jul;8(4):346-352
Click to view abstract

Detection of allergen specific antibodies from nasal secretion of allergic rhinitis patients.  
Kim JH, Yoon MG, Seo DH, Kim BS, Ban GY, Ye YM, Shin YS, Park HS.
Allergy Asthma Immunol Res 2016 Jul;8(4):329-337
Click to view abstract

No concentration decrease of house dust mite allergens with rising altitude in alpine regions.  
Grafetstatter C, Prossegger J, Braunschmid H, Sanovic R, Hahne P, Pichler C, Thalhamer J, Hartl A.
Allergy Asthma Immunol Res 2016 Jul;8(4):312-318
Click to view abstract

Crotoxin: a novel allergen to occupational anaphylaxis.  
de Pontes LG, Cavassan NR, Creste CF, Junior AL, Arcuri HA, Ferreira RS, Barraviera B, Gagete E, Dos Santos LD.
Ann Allergy Asthma Immunol 2016 Apr 6;

Evaluation of drug provocation test-related anxiety in patients with drug hypersensitivity.  
Soyyigit S, Aydin O, Yilmaz I, Ozdemir SK, Cankorur VS, Atbasoglu C, Celik GE.
Ann Allergy Asthma Immunol 2016 Jul 1;
Click to view abstract

Sensitization to mouse and cockroach allergens and asthma morbidity in urban minority youth: Genes-environments and Admixture in Latino American (GALA-II) and Study of African-Americans, Asthma, Genes, and Environments (SAGE-II).  
Fishbein AB, Lee TA, Cai M, Oh SS, Eng C, Hu D, Huntsman S, Farber HJ, Serebrisky D, Silverberg J, Williams LK, Seibold MA, Sen S, Borrell LN, Avila P, Rodriguez-Cintron W, Rodriguez-Santa.
Ann Allergy Asthma Immunol 2016 Jul;117(1):43-49
Click to view abstract

Occupational allergic respiratory disease due to royal jelly.  
Gomez TE, Mendez DY, Borja Segade JM, Feo Brito JF, Alfaya AT, Galindo Bonilla PA, Ledesma FA, Garcia RR.
Ann Allergy Asthma Immunol 2016 Jul;117(1):102-103

Adoptive transfer of food allergy via unrelated allogeneic bone marrow transplant.  
Dholaria B, Bhasin A, Krishna M, Finn L.
Ann Allergy Asthma Immunol 2016 Jul;117(1):96-97

An unusual case of immediate hypersensitivity reaction to a common medication.  
Dass K, Bose S, Ditto AM.
Ann Allergy Asthma Immunol 2016 Jul;117(1):14-16

In vitro rapid diagnostic tests for severe drug hypersensitivity reactions in children.  
Haw WY, Polak ME, McGuire C, Erlewyn-Lajeunesse M, rdern-Jones MR.
Ann Allergy Asthma Immunol 2016 Jul;117(1):61-66
Click to view abstract

Comparison between specific IgE levels and skin prick test results of local and imported American cockroach, dog, cat, dust mites and mold allergen extracts.  
Visitsunthorn N, Sripramong C, Bunnag C, Jirapongsananuruk O.
Asian Pac J Allergy Immunol 2016 Jun 30;
Click to view abstract

IgE-associated food allergy alters the presentation of pediatric eosinophilic esophagitis.  
Pelz BJ, Wechsler JB, Amsden K, Johnson K, Singh AM, Wershil BK, Kagalwalla AF, Bryce PJ.
Clin Exp Allergy 2016 Jul 8;
Click to view abstract

How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results.  
Kespohl S, Maryska S, Bunger J, Hagemeyer O, Jakob T, Joest M, Knecht R, Koschel D, Kotschy-Lang N, Merget R, Mulleneisen NK, Rabe U, Roseler S, Sander I, Stollewerk D, Straube H, Ulmer HM.
Clin Exp Allergy 2016 Jul;46(7):981-991
Click to view abstract

Immediate drug hypersensitivity.  
Wickner PG, Hong D.
Curr Allergy Asthma Rep 2016 Jul;16(7):49
Click to view abstract

The prevalence and natural history of food allergy.  
Kattan J.
Curr Allergy Asthma Rep 2016 Jul;16(7):47
Click to view abstract

Allergen component analysis as a tool in the diagnosis of occupational allergy.  
Raulf M.
Curr Opin Allergy Clin Immunol 2016 Apr;16(2):93-100

Comparison of allergenic extracts from different origins: the value of the FDA's bioequivalent allergy unit (BAU).  
Passalacqua G, Sastre J, Pfaar O, Wahn U, Demoly P.
Expert Rev Clin Immunol 2016 Jul;12(7):733-739
Click to view abstract

The Importance of Amoxicillin and Amoxicillin-Clavulanate Determinants in the Diagnosis of Immediate Allergic Reactions to beta-Lactams.  
Confino-Cohen R, Rosman Y, Lachover I, Meir SK, Goldberg A.
Int Arch Allergy Immunol 2016 Jul 8;170(1):62-66
Click to view abstract

Sensitization to inhalant allergens in schoolchildren with special reference to passive smoking.  
Kawada T.
Int Arch Allergy Immunol 2016 Jul 6;170(1):67-68

Sensitization to food additives in patients with allergy: a study based on skin test and open oral challenge.  
Moghtaderi M, Hejrati Z, Dehghani Z, Dehghani F, Kolahi N.
Iran J Allergy Asthma Immunol 2016 Jun;15(3):198-203
Click to view abstract

First fatalities from tick bite anaphylaxis.  
McGain F, Welton R, Solley GO, Winkel KD.
J Allergy Clin Immunol Pract 2016 Jul;4(4):769-770

Aspirin-exacerbated respiratory disease: not always 'adult-onset'.  
Tuttle KL, Schneider TR, Henrickson SE, Morris D, Abonia JP, Spergel JM, Laidlaw TM.
J Allergy Clin Immunol Pract 2016 Jul;4(4):756-758

Is the prevalence of food allergy not on the rise after all?  
Santos AF, Lack G.
J Allergy Clin Immunol Pract 2016 Jul;4(4):721-722

Can We Clear the Air?  
Eggleston PA.
J Allergy Clin Immunol Pract 2016 Jul;4(4):680-681

Intraoperative anaphylaxis to latex possibly facilitated by the administration of oxytocin and vasopressin.  
Shum M, Ren Z, Achar K, Jerschow E.
J Allergy Clin Immunol Pract 2016 Jul;4(4):773-776

Antibiotics are the most commonly identified cause of perioperative hypersensitivity reactions.  
Kuhlen JL, Camargo CA, Balekian DS, Blumenthal KG, Guyer A, Morris T, Long A, Banerji A.
J Allergy Clin Immunol Pract 2016 Jul;4(4):697-704
Click to view abstract

Allergy to several local anesthetics from the amide group.  
Dominguez-Ortega J, Phillips-Angles E, Gonzalez-Munoz M, Heredia R, Fiandor A, Quirce S.
J Allergy Clin Immunol Pract 2016 Jul;4(4):771-772

Individualized household allergen intervention lowers allergen level but not asthma medication use: a randomized controlled trial.  
DiMango E, Serebrisky D, Narula S, Shim C, Keating C, Sheares B, Perzanowski M, Miller R, DiMango A, Andrews H, Merle D, Liu X, Calatroni A, Kattan M.
J Allergy Clin Immunol Pract 2016 Jul;4(4):671-679
Click to view abstract

House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs.  
Chan TK, Loh XY, Peh HY, Tan WN, Tan WS, Li N, Tay IJ, Wong WS, Engelward BP.
J Allergy Clin Immunol 2016 Jul;138(1):84-96
Click to view abstract

Association of living in a farming environment with asthma incidence in Canadian children.  
Parsons MA, Beach J, Senthilselvan A.
J Asthma 2016 Jul 6;0
Click to view abstract

The prevalence of food allergy and epinephrine auto-injectors in Dutch food-allergic adolescents.  
Saleh-Langenberg J, Bootsma GM, van Ginkel CD, Kollen BJ, Flokstra-de Blok BM, Dubois AE.
Pediatr Allergy Immunol 2016 Jul 5;
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