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 Allergy Advisor Digest - October 2014
Editor: Dr. Harris A. Steinman

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This is a monthly digest of interesting information that is being added to Allergy Advisor. While we add a great deal of information every month, here we highlight some of the more interesting articles.
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Read Occupational skin hazards and prevalence of occupational skin diseases in shoe manufacturing workers in Indonesia.
Read A plausible allergy to peanut revealed only by Immunoblot.
Read IgE, IgG4 and IgA specific for Bet v 1-related food allergens do not predict oral allergy syndrome.
Read Identification of peamaclein as a marker allergen related to systemic reactions in peach allergy.
Read Respiratory disease associated with occupational inhalation to hop (Humulus lupulus) during harvest and processing.
Read How accurate are people at identifying stinging insects?
Read Dissociation between sensitizing and colonizing fungi in patients with allergic bronchopulmonary aspergillosis.
Read Sensitization to laboratory animal allergens among students and researchers exposed to laboratory rodents in Hokkaido University.
Read Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.
Read Anaphylaxis to PR-10 proteins (Bet v1 homologues).
Read Peanut allergy: Effect of environmental peanut exposure in children with filaggrin loss-of-function mutations.
Read Structural aspects of dog allergies: the crystal structure of a dog dander allergen Can f 4.
Read Peanut allergy, not always the correct diagnosis.
Read Skin testing with raw egg does not predict tolerance to baked egg in egg-allergic children.
Read Severe anaphylaxis to cow's milk: about 55 cases reported Allergo-Vigilance Network between 2002 and 2012

Abstracts shared in October 2014 Advisor Digest Newsletter

Read Predictive values of component-specific IgE for the outcome of peanut and hazelnut food challenges in children.
Read Concomitant sensitization to ragweed and mugwort pollen: who is who in clinical allergy?
Read Identification of a novel allergen from muscle and various organs in banana shrimp
Read Infrared camera-proven water-damaged homes are associated with the severity of atopic dermatitis in children.
Read Cetirizine anaphylaxis.
Read The utility of the ISAC allergen array in the investigation of idiopathic anaphylaxis.
Read Hazelnut allergy differs between children and adults.
Read Systemic contact dermatitis to foods: nickel, BOP, and more.
Read Anaphylaxis caused by hidden soybean allergens in pillows.
Read Allergy to furry animals: New insights, diagnostic approaches, and challenges.
Read Anaphylaxis to amoxicillin 31 years after the last accident
Read Allergens involved in a case of latex allergy cross - buckwheat

Allergy and Intolerance Abstracts
Occupational skin hazards and prevalence of occupational skin diseases in shoe manufacturing workers in Indonesia.
Shoe manufacturing workers are exposed daily to an extensive range of potential physical and chemical occupational hazards. In this study, the authors investigated the possible potential exposure of the workers to physical and occupational hazards and determined the prevalence of occupational skin diseases at a shoe manufacturing factory in Indonesia. The risk of Occupational skin diseases (OSD) at the shoe factory was mainly related to the exposure of the workers' skin to potential physical and chemical hazards in hot and humid environmental conditions. From a total of 514 workers, 8.5 % reported current OSD and 4.8 % reported a history of OSD. Occupational skin diseases were diagnosed in 29 % of the workers by dermatologists and 7.6 % had an occupational contact dermatitis (OCD). Of the 39 workers with contact dermatitis, 33 consented to being patch tested, 14 (3 %) workers showed a positive results and considered as having an occupational allergic contact dermatitis (OACD) and 25 (4.9 %) had an occupational irritant contact dermatitis (OICD).

Occupational skin hazards and prevalence of occupational skin diseases in shoe manufacturing workers in Indonesia.  
Febriana SA, Soebono H, Coenraads PJ.
Int Arch Occup Environ Health 2014 Feb;87(2):185-194

Index
Allergy and Intolerance Abstracts
A plausible allergy to peanut revealed only by Immunoblot.
A plausible allergy to peanut revealed only by Immunoblot.

A 49 years old female presented with a systemic reaction including abdominal pain, vomiting, erythema, vertigo and sudation, 2 hours after ingesting approximately 4 g of Curly® (containing 59% maize flour and 30% peanut flour). Prick tests to natural roasted peanut, to peanut commercial extract, to maize flour and to soy were negative. No IgEs were detected to peanut and recombinant allergens: rAra h 1, rAra h 2, rAra h 3, rAra h 8, rAra h 9. Serum IgE to rAra h 6 and rAra h 7 were negative. A basophil activation test to peanut extract was positive. She tolerated an open oral challenge with Curly to 14.3 g of the product (peanut

protein equivalent 3.3 g). Immunoblot assays with peanut, Curly® extracts and bromelain were performed. Different proteins were recognized by the IgE in peanut and Curly® extract. The patient’s sIgE recognizing CCD of bromelain were inhibited by CCD present in peanut and Curly® extract. This might indicate that CCDs were clinically relevant in this case. The authors state that they cannot exclude sensitization to buried protein epitopes, not available to IgE binding in the commercial extract as well in native peanut flour and for prick test. The fact that the oral challenge was negative to 3.3 g of peanut proteins does not exclude allergy in their opinion, since the oral challenge was not associated to alcohol. Alcohol is a well-known risk factor for food anaphylaxis, since it promotes intestinal hyperpermeability and moreover brings more carbohydrate residues.

A plausible allergy to peanut revealed only by Immunoblot.  
Richard C, Jacquenet S, Moneret-Vautrin DA.
Eur Ann Allergy Clin Immunol 2014 Sep;46(5):181-183

Index
Allergy and Intolerance Abstracts
IgE, IgG4 and IgA specific for Bet v 1-related food allergens do not predict oral allergy syndrome.
Birch pollen-associated plant food allergy is caused by Bet v 1-specific IgE, but presence of cross-reactive IgE to related allergens does not predict food allergy. The role of other immunoglobulin isotypes in the birch pollen-plant food syndrome has not been investigated in detail. Bet v 1-sensitised birch pollen-allergic patients (n = 35) were diagnosed for food allergy by standardised interviews, skin prick tests, prick-to-prick tests and ImmunoCAP. Concentrations of allergen-specific IgE, IgG1, IgG4 and IgA to seven Bet v 1-related food allergens were determined by ELISA. Bet v 1, Cor a 1, Mal d 1 and Pru p 1 bound IgE from all and IgG4 and IgA from the majority of sera. Immunoglobulins to Gly m 4, Vig r 1 and Api g 1.01 were detected in less than 65% of the sera. No significant correlation was observed between plant food allergy and increased or reduced levels of IgE, IgG1, IgG4 or IgA specific for most Bet v 1-related allergens. Api g 1-specific IgE was significantly (p = 0.01) elevated in celeriac-allergic compared to celeriac-tolerant patients. Likewise, frequencies of IgE (71% versus 15%; p = 0.01) and IgA (86% versus 38%; p = 0.04) binding to Api g 1.01 were increased. Therefore measurements of allergen-specific immunoglobulins are not suitable for diagnosing Bet v 1-mediated plant food allergy to hazelnut and Rosaceae fruits. In contrast, IgE and IgA to the distantly related allergen Api g 1 correlate with allergy to celeriac.

IgE, IgG4 and IgA specific for Bet v 1-related food allergens do not predict oral allergy syndrome.  
Guhsl EE, Hofstetter G, Lengger N, Hemmer W, Ebner C, Froschl R, Bublin M, Lupinek C, Breiteneder H, Radauer C.
Allergy 2014 Oct 18;

Index
Allergy and Intolerance Abstracts
Identification of peamaclein as a marker allergen related to systemic reactions in peach allergy.
Peamaclein was recently reported as a new peach allergen, Pru p 7, in Italy. This study investigated the correlation between clinical severity and the sensitization to Peamaclein and LTP in Japanese patients with peach allergy.

Patients were divided into 2 groups: the systemic reaction group, in which the patients developed symptoms in more than 2 organs, and the oral group, in which oral symptoms alone after peach ingestion. In the systemic reaction group, Japanese apricots induced severe reactions, as did peaches, but other fruits induced oral symptoms or urticaria alone. In IgE immunoblotting, the IgE-binding band to peamaclein was more frequently detected in the systemic group (6 of 13 [46.2%]) than in the oral group (1 of 16 [6.3%]), but the IgE-binding band to LTP was not detected in either group. A positive response for specific IgE against rPru p 3 was detected in only 1 patient in the systemic group. In contrast, in an ELISA the positivity for IgE specific to Peamaclein was 64.3% (9 of 14 patients) in the systemic group and 12.6% (2 of 16 patients) in the oral group. The positivity for IgE specific to the purified LTP was 14.3% (2 of 14 patients) in the systemic group and 0% in the oral group. The authors conclude that they have identified Peamaclein as a marker associated with the systemic reactions of peach allergy rather than LTP in Japan.

Identification of peamaclein as a marker allergen related to systemic reactions in peach allergy.  
Inomata N, Okazaki F, Moriyama T, Nomura Y, Yamaguchi Y, Honjoh T, Kawamura Y, Narita H, Aihara M.
Ann Allergy Asthma Immunol 2014 Feb;112(2):175-177

Index
Allergy and Intolerance Abstracts
Respiratory disease associated with occupational inhalation to hop (Humulus lupulus) during harvest and processing.
This study describes occupational respiratory disease in hop workers. Fifty-seven cases of respiratory disease associated with hop dust inhalation were reported from 1995 to 2011. Most cases (61%) were diagnosed by the attending health care practitioner as having work-related asthma. Seven percent of cases were diagnosed as chronic obstructive pulmonary disease, and the remaining cases were diagnosed as allergic respiratory disorders (eg, allergic rhinitis) or asthma-associated symptoms (eg, dyspnea). Cases were associated with hop harvesting, secondary hop processing, and indirect exposure. The incidence rate of respiratory disease in hop workers was 15 cases per 10,000 full-time workers, which was 30 times greater than the incidence rate for field vegetable crop workers.

Respiratory disease associated with occupational inhalation to hop (Humulus lupulus) during harvest and processing.  
Reeb-Whitaker CK, Bonauto DK.
Ann Allergy Asthma Immunol 2014 Sep 9;

Click to view abstract

Index
Allergy and Intolerance Abstracts
How accurate are people at identifying stinging insects?
This study supports the general perception that adults are poor discriminators in distinguishing stinging insects and nests with the exception of the honeybee. Men and those participants who reported multiple stings to at least 4 insects were more accurate overall in insect identification

The HIT study: Hymenoptera Identification Test--how accurate are people at identifying stinging insects?  
Baker TW, Forester JP, Johnson ML, Stolfi A, Stahl MC.
Ann Allergy Asthma Immunol 2014 Sep;113(3):267-270

Click to view abstract

Index
Allergy and Intolerance Abstracts
Dissociation between sensitizing and colonizing fungi in patients with allergic bronchopulmonary aspergillosis.
Multiple fungal species can colonize the airway, and dissociation between colonizing and sensitizing species frequently occurs in definitive ABPA. Considering the increased prevalence of azole-resistant Aspergillus spp., administering antifungal drugs that target A. fumigatus without identifying which fungal species colonize the airway might be problematic.

Dissociation between sensitizing and colonizing fungi in patients with allergic bronchopulmonary aspergillosis.  
Matsuse H, Tsuchida T, Fukahori S, Kawano T, Nishino T, Fukushima C, Kohno S.
Ann Allergy Asthma Immunol 2013 Sep;111(3):190-193

Click to view abstract

Index
Allergy and Intolerance Abstracts
Sensitization to laboratory animal allergens among students and researchers exposed to laboratory rodents in Hokkaido University.
Based on a case who developed anaphylaxis after mouse bite which occurred at Hokkaido University, allergic sensitization prevalence for laboratory animals was studied among students and researchers who are exposed to laboratory rodents and rabbit. Questionnaires and specific-IgE antibody test for 555 rodents and/or rabbit handlers from whom informed consent was obtained were studied. Prevalence of positive IgE antibody higher than class 1 to mice, rats, hamsters, guinea pigs, and/or rabbits in the examinees was 14.1% (62/441) , 17.9% (50/279) , 18.8% (6/32) , 17.4% (4/23) , and 11.3% (12/106) , respectively. Moreover, among users of mouse, those who had allergic symptoms during contact with animals resulted in significantly higher positive rate for anti-mouse IgE antibody test than the other (38.1% vs 8.8%) .

Sensitization to laboratory animal allergens among students and researchers exposed to laboratory rodents in Hokkaido University. [Japanese]  
Yoshimura A, Musashi M, Kaneko T, Ohnishi S, Orito C, Kawahara Y, Hashino S, Morimatsu M, Konno S, Arikawa J, Ishii T, Sawamura M, Ueda I.
Arerugi 2014 Sep;63(8):1132-1139

Index
Allergy and Intolerance Abstracts
Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.
Coconut fatty acids diethanolamide [cocamide diethanolamine (cocamide DEA)] is a surface-active derivative of coconut oil that is used in industrial, household and cosmetic products. Cocamide DEA contact allergy has been reported relatively seldom. Allergic reactions to cocamide DEA from test files, and studied the occupation, exposure, concomitant allergic reactions and diagnoses of the positive patients were retrieved. Of the 2572 patients tested, 25 (1%) had an allergic reaction to cocamide DEA. Nineteen patients were occupational cases, and 11 worked in the metal industry. Hand cleansers constituted the main source of sensitization (n = 17). Other sources included two dishwashing liquids, one barrier cream, and one metalworking fluid. Three patients reacted to monoethanolamine and 2 to diethanolamine. Diethanolamine is an impurity of cocamide DEA, and can be found in cocamide DEA-containing products and in commercial patch test substances, which may explain some concomitant reactions.

Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.  
alto-Korte K, Pesonen M, Kuuliala O, Suuronen K.
Contact Dermatitis 2014 Mar;70(3):169-174

Index
Allergy and Intolerance Abstracts
Anaphylaxis to PR-10 proteins (Bet v1 homologues).
Secondary food allergies to PR-10 proteins (Bet v1 homologues) are the most common food allergies in Germany. Clinically they present with an oral allergy syndrome (intraoral pruritus and perhaps swelling). When drinks containing PR-10 proteins are rapidly consumed, for example after sporting activities, large concentrations of allergen can be reached without any intraoral symptoms and then lead to anaphylaxis. This phenomenon has often been described for soy milk and occurred in our case with an apple drink with 60% fruit concentration. It seems likely that such cases of anaphylaxis are not adequately represented in the anaphylaxis registry.

Anaphylaxis to PR-10 proteins (Bet v1 homologues). [German]  
Roseler S, Balakirski G, Plange J, Wurpts G, Baron JM, Megahed M, Merk HF.
Hautarzt 2013 Dec;64(12):890-892

Index
Allergy and Intolerance Abstracts
Peanut allergy: Effect of environmental peanut exposure in children with filaggrin loss-of-function mutations.
Filaggrin (FLG) loss-of-function mutations lead to an impaired skin barrier associated with peanut allergy. Household peanut consumption is associated with peanut allergy, and peanut allergen in household dust correlates with household peanut consumption. This study sought to determine whether environmental peanut exposure increases the odds of peanut allergy and whether FLG mutations modulate these odds. The study concludes that early-life environmental peanut exposure is associated with an increased risk of peanut sensitization and allergy in children who carry an FLG mutation. These data support the hypothesis that peanut allergy develops through transcutaneous sensitization in children with an impaired skin barrier.

Peanut allergy: Effect of environmental peanut exposure in children with filaggrin loss-of-function mutations.  
Brough HA, Simpson A, Makinson K, Hankinson J, Brown S, Douiri A, Belgrave DC, Penagos M, Stephens AC, McLean WH, Turcanu V, Nicolaou N, Custovic A, Lack G.
J Allergy Clin Immunol 2014 Oct;134(4):867-875

Index
Allergy and Intolerance Abstracts
Structural aspects of dog allergies: the crystal structure of a dog dander allergen Can f 4.
Four out of six officially recognized dog allergens are members of the lipocalin protein family. This study reports on the crystal structure of a second lipocalin allergen from dog, a variant of Can f 4. Can f 4 is capable of binding only relatively small hydrophobic molecules which are different from those that Can f 2 is able to bind.

Structural aspects of dog allergies: the crystal structure of a dog dander allergen Can f 4.  
Niemi MH, Rytkonen-Nissinen M, Janis J, Virtanen T, Rouvinen J.
Mol Immunol 2014 Sep;61(1):7-15

Index
Allergy and Intolerance Abstracts
Peanut allergy, not always the correct diagnosis.
Diagnosing peanut allergy in children is complicated. The clinical history can be difficult to interpret, measurement of peanut-specific immunoglobulin E (IgE) is of limited usefulness due to its poor specificity, and the gold standard (double-blind placebo-controlled food challenge) is time-consuming and labour-intensive, limiting its use in daily practice. Under-diagnosing peanut allergy is considered dangerous, because of serious reactions like anaphylaxis. As a result, there is a high probability of over-diagnosis of peanut allergy in the general population, leading to unnecessary peanut-free diets and parental anxiety. The authors discuss three children diagnosed with peanut allergy, and describe the clinical and diagnostic considerations of peanut allergy. After a detailed history focusing on the reproducibility of objective symptoms after exposure, peanut allergy was excluded in two cases allowing normalization of the diet and reduction of patient and parental anxiety.

Peanut allergy, not always the correct diagnosis. [Dutch]  
van Veen WJ, Brand PL.
Ned Tijdschr Geneeskd 2014;158(5):A6748

Index
Allergy and Intolerance Abstracts
Skin testing with raw egg does not predict tolerance to baked egg in egg-allergic children.
This study concludes that skin testing with raw egg does not predict tolerance to baked egg in egg-allergic children. Data were analysed from 186 completed challenges: OFC was positive in 64 (34%) children, negative in 122 (66%). Six children experienced anaphylaxis at OFC. Children tolerant to baked egg were more likely to have a lower SPT to egg extract/raw egg and egg extract (EE):raw egg (RE) than their allergic counterparts. However, ROC curve analysis demonstrated poor predictivity of challenge outcome, with AUC for SPT to egg extract, raw egg and EE:ER equal to 0.71, 0.63 and 0.60 respectively.

Skin testing with raw egg does not predict tolerance to baked egg in egg-allergic children.  
Turner P, Kumar K, Fox A.
Pediatr Allergy Immunol 2014 Oct 9;

Index
Allergy and Intolerance Abstracts
Severe anaphylaxis to cow's milk: about 55 cases reported Allergo-Vigilance Network between 2002 and 2012
"We present 55 cases of anaphylaxis to cow's milk, a large majority in children, which were reported to the Allergy Vigilance Network between 2002 and 2012. We have analyzed the clinical characteristics and the circumstances of these anaphylactic reactions (severe; dietary or labeling error). In order to prevent anaphylactic reactions by elimination, we propose some other possibilities (for example, early introduction of cow's milk for breast-fed infants?) and we emphasize the importance of parental education to avoid dietary errors in cases of known allergy."

Anaphylaxie sévère au lait de vache : à propos de 55 cas déclarés au Réseau d’Allergo-Vigilance entre 2002 et 2012 / Severe anaphylaxis to cow's milk: about 55 cases reported Allergo-Vigilance Network between 2002 and 2012  
D. Sabouraud-Leclerc, V. Liabeuf, A. Hoppé, L. Guénard, A. Chabbert-Broué, J.-M. Renaudin, J. Gayraud, D.-A. Moneret-Vautrin
Rev Fr Allergol 2014;54(6):423-427

Click to view abstract Click to view abstract

Index

Allergen-, Food allergy-, Intolerance-related articles

Occupational skin hazards and prevalence of occupational skin diseases in shoe manufacturing workers in Indonesia.  
Febriana SA, Soebono H, Coenraads PJ.
Int Arch Occup Environ Health 2014 Feb;87(2):185-194

Hypersensitivity pneumonitis in a cluster of sawmill workers: a 10-year follow-up of exposure, symptoms, and lung function.  
Faerden K, Lund MB, Mogens AT, Eduard W, Sostrand P, Langard S, Kongerud J.
Int J Occup Environ Health 2014 Apr;20(2):167-173

Prevalence and Risk Factors of Asthma and Allergic Diseases in Primary Schoolchildren Living in Bushehr, Iran: Phase I, III ISAAC Protocol.  
Farrokhi S, Gheybi MK, Movahhed A, Dehdari R, Gooya M, Keshvari S, Gholampour H, Mansourian Z, Khosravi Y, Ghahramani F, Zandi S, Etemadan R, Tahmasebi R, Reaisi A, Keshmiri S, Fadaizadeh L, .
Iran J Allergy Asthma Immunol 2014 Oct;13(5):348-355

A plausible allergy to peanut revealed only by Immunoblot.  
Richard C, Jacquenet S, Moneret-Vautrin DA.
Eur Ann Allergy Clin Immunol 2014 Sep;46(5):181-183

IgE, IgG4 and IgA specific for Bet v 1-related food allergens do not predict oral allergy syndrome.  
Guhsl EE, Hofstetter G, Lengger N, Hemmer W, Ebner C, Froschl R, Bublin M, Lupinek C, Breiteneder H, Radauer C.
Allergy 2014 Oct 18;

Predictive values of component-specific IgE for the outcome of peanut and hazelnut food challenges in children.  
Beyer K, Grabenhenrich L, Beder A, Kalb B, Ziegert M, Finger A, Harandi N, Schlags R, Gappa M, Puzzo L, Roblitz H, Millner-Uhlemann M, Busing S, Ott H, Lange L, Niggemann B.
Allergy 2014 Oct 13;

Lactic acidosis after inhaled beta-2 agonists: about 2 cases. [French]  
Moustafa F, Garrouste C, Bertrand PM, Kauffmann S, Schmidt J.
Ann Fr Anesth Reanim 2014 Jan;33(1):49-51

Identification of peamaclein as a marker allergen related to systemic reactions in peach allergy.  
Inomata N, Okazaki F, Moriyama T, Nomura Y, Yamaguchi Y, Honjoh T, Kawamura Y, Narita H, Aihara M.
Ann Allergy Asthma Immunol 2014 Feb;112(2):175-177

Allergen of the month--field maple.  
Weber RW.
Ann Allergy Asthma Immunol 2014 Sep;113(3):A15

Nasal allergen challenge studies of allergic rhinitis: a guide for the practicing clinician.  
Soliman M, North ML, Steacy LM, Thiele J, Adams DE, Ellis AK.
Ann Allergy Asthma Immunol 2014 Sep;113(3):250-256

Concomitant sensitization to ragweed and mugwort pollen: who is who in clinical allergy?  
Asero R, Bellotto E, Ghiani A, Aina R, Villalta D, Citterio S.
Ann Allergy Asthma Immunol 2014 Sep;113(3):307-313
Click to view abstract

Relationship of pediatric eosinophilic esophagitis diagnosis to pollen and mold counts.  
Schlegel CR, Quintanilla NM, Olive AP, Minard CG, Davis CM.
Ann Allergy Asthma Immunol 2014 Sep;113(3):321-322

Angler fish is not an alternative in allergy to multiple fish species.  
Azofra J, Maroto AS, Vivanco F, Pastor-Vargas C.
Ann Allergy Asthma Immunol 2014 Sep;113(3):323-324

Identification of a novel allergen from muscle and various organs in banana shrimp (Fenneropenaeus merguiensis).  
Khanaruksombat S, Srisomsap C, Chokchaichamnankit D, Punyarit P, Phiriyangkul P.
Ann Allergy Asthma Immunol 2014 Sep;113(3):301-306
Click to view abstract

Allergen of the month--meadow fescue.  
Weber RW.
Ann Allergy Asthma Immunol 2014 Jul;113(1):A11

Trimethoprim-sulfamethoxazole-induced aseptic meningitis-not just another sulfa allergy.  
Bruner KE, Coop CA, White KM.
Ann Allergy Asthma Immunol 2014 Sep 17;
Click to view abstract

Ambrosia pollen in Tulsa, Oklahoma: aerobiology, trends, and forecasting model development.  
Howard LE, Levetin E.
Ann Allergy Asthma Immunol 2014 Sep 17;
Click to view abstract

Anaphylaxis caused by hemocyanin contained in shrimp cephalothorax.  
Guillen D, Fiandor A, Del P, Pedrosa M, Phillips-Angles E, Caballero T, Quirce S.
Ann Allergy Asthma Immunol 2014 Oct 9;

Correlation of clinical monosensitivity to cod with specific IgE to enolase and aldolase.  
Kuehn A, Fischer J, Hilger C, Sparla C, Biedermann T, Hentges F.
Ann Allergy Asthma Immunol 2014 Oct 7;

Mouse allergen exposure and decreased risk of allergic rhinitis in school-aged children.  
Jacobs TS, Forno E, Brehm JM, costa-Perez E, Han YY, Blatter J, Thorne P, Metwali N, Colon-Semidey A, Alvarez M, Canino G, Celedon JC.
Ann Allergy Asthma Immunol 2014 Oct 7;
Click to view abstract

Recurrent angioedema after naproxen use in a patient stabilized with losartan.  
Venci JV, Shamaskin JA.
Ann Allergy Asthma Immunol 2014 Oct 1;

Allergen of the month-utah juniper.  
Weber RW.
Ann Allergy Asthma Immunol 2014 Oct;113(4):A21

Air pollution and asthma: how can a public health concern inform the care of individual patients?  
North ML, Alexis NE, Ellis AK, Carlsten C.
Ann Allergy Asthma Immunol 2014 Oct;113(4):343-346

Safety and clinical predictors of reacting to extensively heated cow's milk challenge in cow's milk-allergic children.  
Mehr S, Turner PJ, Joshi P, Wong M, Campbell DE.
Ann Allergy Asthma Immunol 2014 Oct;113(4):425-429
Click to view abstract

Infrared camera-proven water-damaged homes are associated with the severity of atopic dermatitis in children.  
Seo S, Han Y, Kim J, Choung JT, Kim BJ, Ahn K.
Ann Allergy Asthma Immunol 2014 Sep 9;
Click to view abstract

Respiratory disease associated with occupational inhalation to hop (Humulus lupulus) during harvest and processing.  
Reeb-Whitaker CK, Bonauto DK.
Ann Allergy Asthma Immunol 2014 Sep 9;
Click to view abstract

Risk of allergic reaction and sensitization to antibiotics in foods.  
Graham F, Paradis L, Begin P, Paradis J, Babin Y, Des RA.
Ann Allergy Asthma Immunol 2014 Sep;113(3):329-330

Cetirizine anaphylaxis.  
Rutkowski K, Wagner A.
Ann Allergy Asthma Immunol 2014 Sep;113(3):247-249

Multinational experience with hypersensitivity drug reactions in Latin America.  
Jares EJ, Sanchez-Borges M, Cardona-Villa R, Ensina LF, rias-Cruz A, Gomez M, Barayazarra S, Bernstein JA, Serrano CD, Cuello MN, Morfin-Maciel BM, De FA, Cherrez-Ojeda I.
Ann Allergy Asthma Immunol 2014 Sep;113(3):282-289
Click to view abstract

Delayed clavulanic acid-induced anaphylaxis in a patient undergoing bariatric surgery.  
Mobayed H, Ibrahim W, Al-Nesf M.
Ann Allergy Asthma Immunol 2014 Sep;113(3):324-325

Factors related to histamine concentrations for positive control in prick-puncture skin testing.  
Hein GL.
Ann Allergy Asthma Immunol 2014 Sep;113(3):332

Elevated platelet activation in patients with chronic urticaria: a comparison between aspirin-intolerant and aspirin-tolerant groups.  
Palikhe S, Palikhe NS, Kim SH, Yoo HS, Shin YS, Park HS.
Ann Allergy Asthma Immunol 2014 Sep;113(3):276-281
Click to view abstract

Association of serum periostin with aspirin-exacerbated respiratory disease.  
Kim MA, Izuhara K, Ohta S, Ono J, Yoon MK, Ban GY, Yoo HS, Shin YS, Ye YM, Nahm DH, Park HS.
Ann Allergy Asthma Immunol 2014 Sep;113(3):314-320
Click to view abstract

The HIT study: Hymenoptera Identification Test--how accurate are people at identifying stinging insects?  
Baker TW, Forester JP, Johnson ML, Stolfi A, Stahl MC.
Ann Allergy Asthma Immunol 2014 Sep;113(3):267-270
Click to view abstract

The dry needle technique.  
Coop CA, Yip SK, Tankersley MS.
Ann Allergy Asthma Immunol 2014 Jul;113(1):120-121

Contact hypersensitivity to triclosan.  
Buhl T, Fuchs T, Geier J.
Ann Allergy Asthma Immunol 2014 Jul;113(1):119-120

Serum specific IgG response to toluene diisocyanate-tissue transglutaminase conjugate in toluene diisocyanate-induced occupational asthmatics.  
Pham lD, Kim MA, Yoon MG, Lee SI, Shin YS, Park HS.
Ann Allergy Asthma Immunol 2014 Jul;113(1):48-54
Click to view abstract

Allergen of the month-harvester ant.  
Weber RW.
Ann Allergy Asthma Immunol 2013 Sep;111(3):A19

Measurement of immunoglobulin E interaction with allergen extracts by surface plasmon resonance biosensor analysis.  
Iraola V, Gallego MT, Taules M, Carnes J.
Ann Allergy Asthma Immunol 2013 Sep;111(3):228-229

Contact dermatitis to vitamin K1 in an eye cream.  
Lopez-Lerma I, Vilaplana J.
Ann Allergy Asthma Immunol 2013 Sep;111(3):227-228

A case of anaphylaxis to erythritol diagnosed by CD203c expression-based basophil activation test.  
Sugiura S, Kondo Y, Ito K, Hashiguchi A, Takeuchi M, Koyama N.
Ann Allergy Asthma Immunol 2013 Sep;111(3):222-223

Longitudinal study of 954 patients with stinging insect anaphylaxis.  
Rudders SA, Clark S, Wei W, Camargo CA.
Ann Allergy Asthma Immunol 2013 Sep;111(3):199-204
Click to view abstract

Factors associated with reported food allergy tolerance among US children.  
Gupta RS, Lau CH, Sita EE, Smith B, Greenhawt MJ.
Ann Allergy Asthma Immunol 2013 Sep;111(3):194-198
Click to view abstract

Dissociation between sensitizing and colonizing fungi in patients with allergic bronchopulmonary aspergillosis.  
Matsuse H, Tsuchida T, Fukahori S, Kawano T, Nishino T, Fukushima C, Kohno S.
Ann Allergy Asthma Immunol 2013 Sep;111(3):190-193
Click to view abstract

Refractoriness to inhaled mannitol 3 hours after allergen challenge.  
Amakye DO, Davis BE, Martin AL, Peters GE, Cockcroft DW.
Ann Allergy Asthma Immunol 2013 Sep;111(3):182-184
Click to view abstract

Importance of establishing threshold levels for food allergens.  
Greenhawt M, Weiss C.
Ann Allergy Asthma Immunol 2013 Sep;111(3):151-154

Allergen of the month--Wych elm.  
Weber RW.
Ann Allergy Asthma Immunol 2013 Mar;110(3):A27

Intractable shellfish anaphylaxis: sensitization by cross-reactive substances in a complementary 'immune stimulant' and acrylic nails.  
Rolland JM, Varese N, Zubrinich CM, O'Hehir RE.
Ann Allergy Asthma Immunol 2013 Mar;110(3):211-212

In vivo tests with 'Tahini' sauce: new allergenic source to evaluate IgE-mediated hypersensitivity to sesame.  
la-Torre E, Pignatti P, Yacoub MR, Sabbadini MG, Colombo G.
Ann Allergy Asthma Immunol 2013 Mar;110(3):209-210

Goji berry: a potential new player in latex-food syndrome.  
Gamez C, Marchan E, Miguel L, Sanz V, Del P.
Ann Allergy Asthma Immunol 2013 Mar;110(3):206-207

Relating microarray component testing and reported food allergy and food-triggered atopic dermatitis: a real-world analysis.  
Fung I, Kim JS, Spergel JM.
Ann Allergy Asthma Immunol 2013 Mar;110(3):173-177
Click to view abstract

Images in emergency medicine. Young woman with cardiac arrest. Defatting dermatitis as a result of chloroform exposure.  
Greene SC, White NR.
Ann Emerg Med 2014 Sep;64(3):231, 247

Sensitization to laboratory animal allergens among students and researchers exposed to laboratory rodents in Hokkaido University. [Japanese]  
Yoshimura A, Musashi M, Kaneko T, Ohnishi S, Orito C, Kawahara Y, Hashino S, Morimatsu M, Konno S, Arikawa J, Ishii T, Sawamura M, Ueda I.
Arerugi 2014 Sep;63(8):1132-1139

Progress of the research on air pollution (pm2.5, asian sand dust, etc) and allergy. [Japanese]  
Ichinose T.
Arerugi 2014 Sep;63(8):1085-1094

Epidemiological studies on the environmental pollutants and allergies: focused on indoor air quality. [Japanese]  
Araki A, Bamai YA, Kishi R.
Arerugi 2014 Sep;63(8):1075-1084

Point-of-care vertical flow allergen microarray assay: proof of concept.  
Chinnasamy T, Segerink LI, Nystrand M, Gantelius J, Andersson SH.
Clin Chem 2014 Sep;60(9):1209-1216

The utility of the ISAC allergen array in the investigation of idiopathic anaphylaxis.  
Heaps A, Carter S, Selwood C, Moody M, Unsworth J, Deacock S, Sumar N, Bansal A, Hayman G, El-Shanawany T, Williams P, Kaminski E, Jolles S.
Clin Exp Immunol 2014 Aug;177(2):483-490

Hazelnut allergy differs between children and adults in frequency of severity, aetiology and relevance of diagnostic parameters.  
Masthoff LJ, van HE, de RA, Boonacker CW, Bruijnzeel-Koomen CA, Pasmans SG, Knulst AC.
Clin Exp Allergy 2014 Oct 21;

Aminopenicillin-associated exanthem: lymphocyte transformation testing revisited.  
Trautmann A, Seitz CS, Stoevesandt J, Kerstan A.
Clin Exp Allergy 2014 Oct 16;

Local and systemic effects of cat allergen nasal provocation.  
Scadding GW, Eifan A, Penagos M, Dumitru A, Switzer A, McMahon O, Phippard D, Togias A, Durham SR, Shamji MH.
Clin Exp Allergy 2014 Oct 9;

Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model.  
Namvar S, Warn P, Farnell E, Bromley M, Bowyer P, Herrick S.
Clin Exp Allergy 2014 Oct 1;

Allergic contact dermatitis caused by self-adhesive electrocardiography electrodes: a rare case with concomitant roles of nickel and acrylates.  
Ozkaya E, Kavlak BP.
Contact Dermatitis 2014 Feb;70(2):121-123

Allergic contact cheilitis caused by polysilicone-15 (Parsol(R) SLX) in a lipcare balm.  
Sarre ME, Guerin-Moreau M, Lepoittevin JP, Martin L, venel-Audran M.
Contact Dermatitis 2014 Feb;70(2):119-121

Allergic contact dermatitis resulting from multiple colophonium-related allergen sources.  
Vandebuerie L, Aerts C, Goossens A.
Contact Dermatitis 2014 Feb;70(2):117-119

Fragrance allergy and quality of life - a case-control study.  
Heisterberg MV, Menne T, Johansen JD.
Contact Dermatitis 2014 Feb;70(2):81-89

The methylisothiazolinone epidemic: Is the fire out or is Rome still burning?  

Contact Dermatitis 2014 Feb;70(2):67-68

Protein contact dermatitis caused by worms and insects used to feed exotic birds.  
Bregnbak D, Friis UF, Zachariae C, Menne T, Johansen JD.
Contact Dermatitis 2014 Jan;70(1):64-66

Hexavalent chromium in leather is now regulated in European Union member states to limit chromium allergy and dermatitis.  
Thyssen JP, Menne T, Johansen JD.
Contact Dermatitis 2014 Jan;70(1):1-2

Triethylene glycol bis(2-ethylhexanoate) - a new contact allergen identified in a spectacle frame.  
Andersen KE, Vestergaard ME, Christensen LP.
Contact Dermatitis 2014 Feb;70(2):112-116

A survey of exposures related to recognized occupational contact dermatitis in Denmark in 2010.  
Caroe TK, Ebbehoj N, Agner T.
Contact Dermatitis 2014 Jan;70(1):56-62

Wet work and hand eczema in apprentice nurses; part I of a prospective cohort study.  
Visser MJ, Verberk MM, van Dijk FJ, Bakker JG, Bos JD, Kezic S.
Contact Dermatitis 2014 Jan;70(1):44-55

Allergic contact dermatitis in Danish children referred for patch testing - a nationwide multicentre study.  
Simonsen AB, Deleuran M, Mortz CG, Johansen JD, Sommerlund M.
Contact Dermatitis 2014 Feb;70(2):104-111

Systemic allergic dermatitis caused by Apiaceae root vegetables.  
Paulsen E, Petersen TH, Frette XC, Andersen KE, Christensen LP.
Contact Dermatitis 2014 Feb;70(2):98-103

Topical botanically derived products: use, skin reactions, and usefulness of patch tests. A multicentre Italian study.  
Corazza M, Borghi A, Gallo R, Schena D, Pigatto P, Lauriola MM, Guarneri F, Stingeni L, Vincenzi C, Foti C, Virgili A.
Contact Dermatitis 2014 Feb;70(2):90-97

No remarkable differences in rates of sensitization to common type I and IV allergens between FLG loss-of-function mutation carriers and wild-type subjects.  
Landeck L, Visser M, Skudlik C, Brans R, Kezic S, John SM.
Contact Dermatitis 2014 Jan;70(1):27-34

Fragrance allergy and quality of life - development and validation of a disease-specific quality of life instrument.  
Heisterberg MV, Menne T, Johansen JD.
Contact Dermatitis 2014 Feb;70(2):69-80

Allergic chromium dermatitis from wearing 'chromium-free' footwear.  
Thyssen JP, Jellesen MS, Moller P, Menne T, Johansen JD.
Contact Dermatitis 2014 Mar;70(3):185-187

An epidemic of contact allergy to methylisothiazolinone in Finland.  
Lammintausta K, alto-Korte K, Ackerman L, Alanko K, Berry P, Hasan T, Kaminska R, Korhonen L, Laukkanen A, Liippo J, Pesonen M, Rantanen T, Riekki R, Suuronen K.
Contact Dermatitis 2014 Mar;70(3):184-185

Airborne allergic contact dermatitis caused by methylisothiazolinone in a child sensitized from wet wipes.  
Madsen JT, Andersen KE.
Contact Dermatitis 2014 Mar;70(3):183-184

Allergic contact dermatitis caused by alkyl glucosides.  
Gijbels D, Timmermans A, Serrano P, Verreycken E, Goossens A.
Contact Dermatitis 2014 Mar;70(3):175-182

Occupational allergic contact dermatitis caused by coconut fatty acids diethanolamide.  
alto-Korte K, Pesonen M, Kuuliala O, Suuronen K.
Contact Dermatitis 2014 Mar;70(3):169-174

Air-oxidized linalool elicits eczema in allergic patients - a repeated open application test study.  
Andersch BY, Hagvall L, Siwmark C, Niklasson B, Karlberg AT, Brared CJ.
Contact Dermatitis 2014 Mar;70(3):129-138

Severe recurrence of drug rash with eosinophilia and systemic symptoms syndrome secondary to rifampicin patch testing in a human immunodeficiency virus-infected man.  
Shebe K, Ngwanya MR, Gantsho N, Lehloenya RJ.
Contact Dermatitis 2014 Feb;70(2):125-127

Systemic allergic dermatitis resulting from oral administration of chromium with a food supplement.  
De MS, Cecchin E, De Marchi SU.
Contact Dermatitis 2014 Feb;70(2):123-125

Managing food allergies in schools.  
Portnoy JM, Shroba J.
Curr Allergy Asthma Rep 2014 Oct;14(10):467

Systemic contact dermatitis to foods: nickel, BOP, and more.  
Fabbro SK, Zirwas MJ.
Curr Allergy Asthma Rep 2014 Oct;14(10):463

New laboratory methods of diagnosing allergic disease - part i - where we are now?  
Cathy van Rooyen
Current Allergy and Clinical Immunology 2014;27(1):16 -
Click to view abstract Click to view abstract

New laboratory methods of diagnosing allergic disease - part ii - where are we going?  
Cathy van Rooyen
Current Allergy and Clinical Immunology 2014;27(1):20-
Click to view abstract Click to view abstract

Occupational contact dermatitis among nurses: a report of two cases  
Dorothy Ngajilo
Current Allergy and Clinical Immunology 2014;27(1):42-
Click to view abstract Click to view abstract

Food allergy in atopic dermatitis: how, when and why do we test?  
Claudia L Gray, Michael E Levin
Current Allergy and Clinical Immunology 2014;27(2):82-
Click to view abstract Click to view abstract

A review of respiratory health effects in poultry workers  
Dorothy Ngajilo
Current Allergy and Clinical Immunology 2014;27(2):116-
Click to view abstract Click to view abstract

A review of the induction of tolerance of IgE mediated food allergy - past, present and future  

Current Allergy and Clinical Immunology 2014;27(3):162-
Click to view abstract Click to view abstract

Epidemiology of food allergy  
Claudia L Gray, Michael E Levin
Current Allergy and Clinical Immunology 2014;27(3):162-
Click to view abstract Click to view abstract

Influenza vaccination in egg-allergic patients: current guidelines, case report and discussion  
Talita A Ferreira-van der Watt, Claudia L Gray, Michael E Levin
Current Allergy and Clinical Immunology 2014;27(3):172-
Click to view abstract Click to view abstract

Rubber additive contact dermatitis  
Roxanne C de Silva
Current Allergy and Clinical Immunology 2014;27(3):196-
Click to view abstract Click to view abstract

Diagnostic testing in allergy - update 2014  
Di Hawarden
Current Allergy and Clinical Immunology 2014;27(3):216-
Click to view abstract Click to view abstract

Occupational and non-occupational allergic contact dermatitis: a follow-up study.  
Macan J, Rimac D, Kezic S, Varnai VM.
Dermatology 2013;227(4):321-329

Food intolerances. [German]  
Bischoff SC.
Dtsch Med Wochenschr 2014 Aug;139(31-32):1596-1598

Anaphylaxis to PR-10 proteins (Bet v1 homologues). [German]  
Roseler S, Balakirski G, Plange J, Wurpts G, Baron JM, Megahed M, Merk HF.
Hautarzt 2013 Dec;64(12):890-892

Food allergy or food intolerance...?  
S. N. Gaur, Raj Kumar
Indian J Allergy Asthma Immunol 2013;27(2):93
Click to view abstract Click to view abstract

Prevalence of food intolerance in bronchial asthma in india  
Raj Kumar, Mandeep Singh, Nitesh Gupta, Manoj Kumar, Indu Bisht, Shailendra Nath Gaur
Indian J Allergy Asthma Immunol 2013;27(2):121
Click to view abstract

Identification of different pigeon allergens and its trigger toward increase in inner city Asthma  
Sudha Shrikant Deo, Pramod V. Niphadkar, Sujatha Ramesh, Naveen Arora, Amol M. Kakade, Chaitali Mulay, Umakant L. Nadkar, Meghna Repal, Sonali Prabhudesai, Varsha Pandya.
Indian J Allergy Asthma Immunol 2013;28(1):40
Click to view abstract Click to view abstract

A case of wheat-dependent exercise-induced anaphylaxis  
Zareen Mohamed, M. Sathiya
Indian J Allergy Asthma Immunol 2013;28(1):52-
Click to view abstract

Multi-allergen detection in food by micro high-performance liquid chromatography coupled to a dual cell linear ion trap mass spectrometry.  
Monaci L, Pilolli R, De AE, Godula M, Visconti A.
J Chromatogr A 2014 Sep 5;1358136-144

Anaphylaxis caused by hidden soybean allergens in pillows.  
Armentia A, Pineda F, Martin B, San MA, Martin Gil FJ, Puente Y, de LC, Palacios R.
J Allergy Clin Immunol 2012 Oct 26;

Milk allergy is associated with decreased growth in US children.  
Robbins KA, Wood RA, Keet CA.
J Allergy Clin Immunol 2014 Oct 10;

Peanut allergy: Effect of environmental peanut exposure in children with filaggrin loss-of-function mutations.  
Brough HA, Simpson A, Makinson K, Hankinson J, Brown S, Douiri A, Belgrave DC, Penagos M, Stephens AC, McLean WH, Turcanu V, Nicolaou N, Custovic A, Lack G.
J Allergy Clin Immunol 2014 Oct;134(4):867-875

Allergy to furry animals: New insights, diagnostic approaches, and challenges.  
Konradsen JR, Fujisawa T, van Hage M, Hedlin G, Hilger C, Kleine-Tebbe J, Matsui EC, Roberts G, Ronmark E, Platts-Mills T.
J Allergy Clin Immunol 2014 Oct 1;

Prevalence of aspirin-exacerbated respiratory disease among asthmatic patients: A meta-analysis of the literature.  
Rajan JP, Wineinger NE, Stevenson DD, White AA.
J Allergy Clin Immunol 2014 Oct 2;

IgE antibodies to mountain cedar pollen predominantly recognize multiple conformational epitopes on Jun a 1.  
Goldblum RM, Ning B, Endsley MA, Estes DM, Judy BM, van BJ, Midoro-Horiuti T.
J Allergy Clin Immunol 2014 Oct;134(4):967-969

Egg allergy: an update.  
Tan JW, Joshi P.
J Paediatr Child Health 2014 Jan;50(1):11-15

Structural aspects of dog allergies: the crystal structure of a dog dander allergen Can f 4.  
Niemi MH, Rytkonen-Nissinen M, Janis J, Virtanen T, Rouvinen J.
Mol Immunol 2014 Sep;61(1):7-15

Peanut allergy, not always the correct diagnosis. [Dutch]  
van Veen WJ, Brand PL.
Ned Tijdschr Geneeskd 2014;158(5):A6748

Skin testing with raw egg does not predict tolerance to baked egg in egg-allergic children.  
Turner P, Kumar K, Fox A.
Pediatr Allergy Immunol 2014 Oct 9;

The predictive value of allergen skin prick tests and IgE tests at pre-school age: the PACT study.  
Ro AD, Simpson MR, Storro O, Johnsen R, Videm V, Oien T.
Pediatr Allergy Immunol 2014 Oct 9;

Natural history of allergic sensitization in infants with early-onset atopic dermatitis: results from ORCA Study.  
Just J, slandes-Boutmy E, Amat F, Desseaux K, Nemni A, Bourrat E, Sahraoui F, Panse I, Bagot M, Fouere S.
Pediatr Allergy Immunol 2014 Oct 6;

Negative predictive value of drug provocation tests in children.  
Misirlioglu ED, Toyran M, Capanoglu M, Kaya A, Civelek E, Kocabas CN.
Pediatr Allergy Immunol 2014 Oct 6;

Think twice: misleading food-induced respiratory symptoms in children with food allergy.  
Ahrens B, Mehl A, Lau S, Kroh L, Magdorf K, Wahn U, Beyer K, Niggemann B.
Pediatr Pulmonol 2014 Mar;49(3):E59-E62

Fungal sensitization in childhood persistent asthma is associated with disease severity.  
Vicencio AG, Santiago MT, Tsirilakis K, Stone A, Worgall S, Foley EA, Bush D, Goldman DL.
Pediatr Pulmonol 2014 Jan;49(1):8-14

Anaphylaxie sévère au lait de vache : à propos de 55 cas déclarés au Réseau d’Allergo-Vigilance entre 2002 et 2012 / Severe anaphylaxis to cow's milk: about 55 cases reported Allergo-Vigilance Network between 2002 and 2012  
D. Sabouraud-Leclerc, V. Liabeuf, A. Hoppé, L. Guénard, A. Chabbert-Broué, J.-M. Renaudin, J. Gayraud, D.-A. Moneret-Vautrin
Rev Fr Allergol 2014;54(6):423-427
Click to view abstract Click to view abstract

Anaphylaxie à l’amoxicilline 31 ans après le dernier accident / Anaphylaxis to amoxicillin 31 years after the last accident  
A. Bernède, P. Pralong, C. Chérih, A.-L. Breton, J.-F. Nicolas, F. Bérard
Rev Fr Allergol 2014;54(6):451-453
Click to view abstract Click to view abstract

Étude des allergènes impliqués dans un cas d’allergie croisée latex – sarrasin / Study of allergens involved in a case of latex allergy cross - buckwheat  
V. Doyen, K. Lièvre, F. de Thier, C. Ledent, M. Mairesse, F. Corazza, O. Michel, V. Leduc
Rev Fr Allergol 2014;54(6):454-456
Click to view abstract Click to view abstract

Diagnostic des allergies aux hyménoptères. Pour une mise à jour des recommandations de bonnes pratiques / Diagnosing allergies Hymenoptera. For an update of recommendations for good practice  
M. Patural, C. Lambert, C. Dzviga, et le Groupe des insectes piqueurs (ANAFORCAL et SFA)
Rev Fr Allergol 2014;54(6):469-476
Click to view abstract Click to view abstract

Anaphylaxis after intramuscular injection of diclofenac sodium.  
Colak S, Gunes H, Afacan MA, Kandis H, Erdogan MO, Ayranci M, Saritas A.
Am J Emerg Med 2014 Jul;32(7):815-2

Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II.  
Le MN, Carsin AE, Siroux V, Radon K, Norback D, Toren K, Olivieri M, Urrutia I, Cazzoletti L, Jacquemin B, Benke G, Kromhout H, Mirabelli MC, Mehta AJ, Schlunssen V, Sigsgaard T, Blanc PD, Kog.
Eur Respir J 2014 Feb;43(2):374-386

Bet v 1 from birch pollen is a lipocalin-like protein acting as allergen only when devoid of iron by promoting Th2 lymphocytes.  
Roth-Walter F, Gomez-Casado C, Pacios LF, Mothes-Luksch N, Roth GA, Singer J, az-Perales A, Jensen-Jarolim E.
J Biol Chem 2014 Jun 20;289(25):17416-17421

Allergy-associated T cell epitope repertoires are surprisingly diverse and include non-IgE reactive antigens  
April Frazier, Veronique Schulten, Denise Hinz, Carla Oseroff, John Sidney, Bjoern Peters, and Alessandro Sette
WAO Journal 2014;10:14
Click to view abstract Click to view abstract


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