|
 |
| | Allergy Advisor Digest - April 2011
Editor: Dr. Harris A. Steinman |
Previous Issues | All
January 2010
February 2010
March 2010
April 2010
May 2010
June 2010
July 2010
August 2010
September 2010
October 2010
November 2010
December 2010
January 2011
February 2011
March 2011
April 2011
May 2011
June 2011
July 2011
August 2011
September 2011
October 2011
November 2011
December 2011
January 2012
February 2012
March 2012
April 2012
May 2012
June 2012
July 2012
August 2012
September 2012
October 2012
November 2012
December 2012
January 2013
February 2013
March 2013
April 2013
This is a monthly digest of interesting information that is being added to Allergy Advisor. While we add a great deal of information every month, here we highlight some of the more interesting articles.
Want to subscribe to our reminder service? Tell a Friend!
Search
|
| | Diamine oxidase gene with diamine oxidase serum activities. |
|
| | Pet shop workers: exposure, sensitization, and work-related symptoms. |
|
| | Diagnosing of bakers' respiratory allergy: Is specific inhalation challenge test essential? |
|
| | Cyanobacteria: An unrecognized ubiquitous sensitizing allergen? |
|
| | Mold and Alternaria skin test reactivity and asthma in children in Connecticut. |
|
| | The atopy patch test: is it time to redefine its significance? |
|
| | The complexities of defining atopy in severe childhood asthma. |
|
| | Basophil allergen threshold sensitivity, CD-sens, is a measure of allergen sensitivity in asthma. |
|
| | Can Immunoglobulin E-measurement replace challenge tests in allergic rhinoconjunctivits to grass pollen? |
|
| | Two new recombinant guinea-pig lipocalins, Cav p 2 and Cav p 3, in the diagnosis of guinea-pig allergy. |
|
| | Photo-allergic contact dermatitis caused by isoamyl p-methoxycinnamate in an 'organic' sunscreen. |
|
| | Exposures and reactions to allergens among hairdressing apprentices and matched controls. |
|
| | Update on the diagnosis and treatment of shellfish allergy. |
|
| | The History of IgE |
|
| | New causes of occupational asthma. |
|
| | Testing for cattle allergy: modified diagnostic cutoff levels improve sensitivity. |
|
| | Suitability of different glycoproteins and test systems for detecting cross-reactive carbohydrate determinant-specific ige in hymenoptera venom-allergic patients. |
|
| | Anaphylaxis to Buckwheat in an Atopic Child: A Risk Factor for Severe Allergy to Nuts and Seeds? |
|
| | Malassezia sympodialis thioredoxin-specific T cells are highly cross-reactive to human thioredoxin in atopic dermatitis. |
|
| | Estimating the economic burden of food-induced allergic reactions and anaphylaxis in the United States. |
|
| | Stinging insect hypersensitivity: A practice parameter update 2011. |
|
| | Microarrayed recombinant allergens for diagnostic testing. |
|
| | Anaphylaxis during anesthesia in France: An 8-year national survey. |
|
| | Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood. |
|
| | Identification, recombinant expression, and characterization of the 100 kDa high molecular weight Hymenoptera venom allergens Api m 5 and Ves v 3. |
|
| | Allergy to seminal fluid. |
|
| | Exhaled nitric oxide changes in asthmatic children after drinking a caffeine-containing cola drink. |
|
| | Exercise-dependent anaphylaxis associatiated with the ingestion of figs. |
|
| | New perspectives in the diagnosis of egg allergy |
|
| | Hev b 2 and Hev b 13, two major allergens of latex allergy and latex-fruit syndrome |
|
| | Diagnosis of IgE-reactivity by analysis of molecular components (test ISAC) |
|
|
Diamine oxidase gene with diamine oxidase serum activities.
Histamine intolerance (HIT) is associated with an excess of histamine because of an impaired function of the histamine-degrading enzyme diamine oxidase (DAO). The genetic background of HIT is unknown yet. This study concludes that DAO gene variants strongly influence DAO expression and activity but alone are not sufficient to fully effectuate the potentially associated disease state of HIT, suggesting an interplay of genetic and environmental factors.
Association of single nucleotide polymorphisms in the diamine oxidase gene with diamine oxidase serum activities.
Maintz L, Yu CF, Rodriguez E, Baurecht H, Bieber T, Illig T, Weidinger S, Novak N.
Allergy 2011 Apr 13;
|
 |
|
|
|
Pet shop workers: exposure, sensitization, and work-related symptoms.
The aim was to investigate the frequency of allergic sensitization and respiratory symptoms among pet shop staff and to document their work environment. Fifty nine subjects from 24 pet shops were investigated with a questionnaire and lung function tests and skin prick tests against a panel of common inhalant and pet shop allergens. Fifty-three percent reported nasal symptoms, 34% eye symptoms, and 22% had experienced symptoms indicating asthma. However, only four workers (7%) were previously diagnosed with asthma. One-third reported respiratory symptoms at work, mostly against rodents, birds, insects, and hay, and 29% were sensitized to work-related allergens, mainly rodents and fodder insects, e.g., Zophobas. Atopy and total IgE > 100 kU/l increased prevalence of pet shop sensitization [prevalence ratio (PR) 17 and 5.5, respectively], and atopy increased work-related symptoms (PR 3.2). Endotoxin levels were similar between shops with and without rodents. Exposure to animals outside of work was extensive.
Pet shop workers: exposure, sensitization, and work-related symptoms.
Renstrom A, Olsson M, Hedren M, Johansson SG, van HM.
Allergy 2011 Apr 4;
|
| |
|
|
|
Diagnosing of bakers' respiratory allergy: Is specific inhalation challenge test essential?
Neither SPTs to occupational allergens nor evaluation of serum allergen-specific IgE alone or combined with nonspecific bronchial hyperreactivity are characterized by sufficient diagnostic accuracy to replace the specific inhalation challenge test. For the establishment of a definite diagnosis of baker's asthma, specific challenge testing with occupational allergens should be performed.
Diagnosing of bakers' respiratory allergy: Is specific inhalation challenge test essential?
Wiszniewska M, Nowakowska-Swirta E, Palczynski C, Walusiak-Skorupa J.
Allergy Asthma Proc 2011 Mar;32(2):111-118
|
| |
|
|
|
Cyanobacteria: An unrecognized ubiquitous sensitizing allergen?
This study investigated the prevalence of skin sensitisation using detoxified cyanobacterial reagents in a chronic rhinitis population. Two hundred fifty-nine patients ranging in age between 7 and 78 years old underwent testing. Seventy-four (28.6% of the population) patients were SPT(+) to at least one of the cyanobacteria species. Positive SPTs were present in 86% of patients to Microcystis aeruginosa and 12% of patients to Aphanizomenon-flos aquae. There was a strong association between severity of atopy (number of positive SPTs), having allergic rhinitis and sensitization to one or more cyanobacteria species (p < 0.001). This is the first study to show that cyanobacterial allergenicity resides in nontoxin-containing components of this organism.
Cyanobacteria: An unrecognized ubiquitous sensitizing allergen?
Bernstein JA, Ghosh D, Levin LS, Zheng S, Carmichael W, Lummus Z, Bernstein IL.
Allergy Asthma Proc 2011 Mar;32(2):106-110
|
| |
|
|
|
Mold and Alternaria skin test reactivity and asthma in children in Connecticut.
The objective of this study was to examine the relationship between skin test reactivity (STR) to molds and specifically to Alternaria and asthma severity in a group of ethnically diverse children in Connecticut. Demographics and STR to 14 local allergens, including Alternaria, Penicillium, and mold mix, were obtained for 914 Puerto Rican, African American, and non-Hispanic white children. A total of 126 children (14%) had a positive skin test result to mold, and 58 (6%) demonstrated STR to Alternaria. Compared with non-Hispanic white children, there was no difference in the likelihood of being sensitized to Alternaria for Puerto Rican and African American children. In an adjusted analysis, Alternaria STR was associated with severe, persistent asthma but did not predict increasing asthma severity. STR to cat was also associated with severe persistent asthma. Alternaria STR was associated with severe persistent asthma independent of the total number of positive skin test results.
Mold and Alternaria skin test reactivity and asthma in children in Connecticut.
Lyons TW, Wakefield DB, Cloutier MM.
Ann Allergy Asthma Immunol 2011 Apr;106(4):301-307
|
| |
|
|
|
The atopy patch test: is it time to redefine its significance?
This report concludes that based on the pathophysiology of atopic eczema (AEDS), in which the mechanisms of delayed hypersensitivity are predominant, the atopy patch test (APT) seems to have a greater significance than skin prick tests or in vitro IgE tests in patients with current or past history of AEDS. That different sensitization mechanisms underlie these different clinical expressions seems conceivable. In particular, if mite allergens enter the skin in the presence of a filaggrin-dependent skin barrier dysfunction, the sensitization mechanism seems to be ultimately revealed by a positive APT.
The atopy patch test: is it time to redefine its significance?
Fuiano N, Incorvaia C.
Ann Allergy Asthma Immunol 2011 Apr;106(4):278-282
|
| |
|
|
|
The complexities of defining atopy in severe childhood asthma.
"Background Defining atopy in children with severe, therapy-resistant asthma is complex. There is currently no gold standard test; both skin prick testing (SPT) and allergen-specific IgE (sIgE) are used. Furthermore, atopy is increasingly considered to be a spectrum, not an all-or-none phenomenon. Hypothesis SPTs and sIgE cannot be used interchangeably, and if both tests are not performed, opportunities for intervention will be missed. Furthermore, the severity of atopy will be defined differently by the two tests."
"Methods Cross-sectional study of 47 children with severe, therapy-resistant asthma, mean age 11.8 years, range 5.3-16.6 years, who underwent SPT, and measurement of total and sIgE as part of their clinical work-up."
"Results Overall, 42/47 (89%) were atopic (defined as either one positive SPT or sIgE). There was 98% concordance between the two tests in classifying atopy. When each allergen was considered individually, in 40/200 (20%), the SPT and sIgE results were discordant, most commonly in 25/200 (12.5%), the SPT was negative and the sIgE was positive. House dust mite and cat sensitization were more likely detected by sIgE, but dog sensitization by SPT. When atopy was quantified, the sum of sIgEs compared with the sum of SPT weal diameter showed a moderate correlation (r(2) =0.44, P<0.001). Total IgE increased with an increasing number of positive sIgEs (P=0.028), but not significantly with increasing numbers of positive SPTs."
"Conclusion and Clinical Relevance SPT and sIgE identify group prevalence of atopy equally well; however, for individual allergens, concordance is poor, and when used to quantify atopy, SPTs and sIgE were only moderately correlated. In a clinical setting, if allergen avoidance is contemplated in children with severe, therapy-resistant asthma, both tests should be performed in order to detect sensitization."
The complexities of defining atopy in severe childhood asthma.
Frith J, Fleming L, Bossley C, Ullmann N, Bush A.
Clin Exp Allergy 2011 Apr 8;
|
| |
|
|
|
Basophil allergen threshold sensitivity, CD-sens, is a measure of allergen sensitivity in asthma.
Allergic asthma is IgE-mediated and the IgE-sensitisation is usually demonstrated by skin prick tests (SPT) and IgE antibody determinations in serum. The SPT and IgE-antibody values do not directly predict if the allergy clinically contributes to the asthma. The authors suggest that there is therefore a need for new objective tests that may indicate the clinical importance of an IgE-sensitisation. This study evaluated basophil allergen threshold sensitivity (CD-sens) as a measure of allergen sensitivity in allergic asthma and concludes that CD-sens was found to be an objective marker of airway allergen sensitivity in stable allergic asthmatics, that may be used to predict airway responsiveness when bronchial challenge tests cannot be performed.
Basophil allergen threshold sensitivity, CD-sens, is a measure of allergen sensitivity in asthma.
Dahlen B, Nopp A, Johansson SG, Eduards M, Skedinger M, Adedoyin J.
Clin Exp Allergy 2011 Apr 25;
|
| |
|
|
|
Can Immunoglobulin E-measurement replace challenge tests in allergic rhinoconjunctivits to grass pollen?
The authors of this study investigated whether Timothy pollen-specific IgE (sIgE) determinations may assist in predicting the clinical reactivity in patients with allergic rhinoconjunctivitis (ARC). The study concluded that a dose-response relationship between the levels of sIgE and clinical outcome of timothy allergen exposure could not be established. Although IgE-determination remains an important key element in allergy diagnosis, provocation tests are procedures of choice if the clinical relevance of an allergen has to be confirmed.
Can Immunoglobulin E-measurement replace challenge tests in allergic rhinoconjunctivits to grass pollen?
Huss-Marp J, Darsow U, Brockow K, Pfab F, Weichenmeier I, Schober W, Petersson CJ, Borres MP, Ring J, Behrendt H.
Clin Exp Allergy 2011 Apr 25;
|
| |
|
|
|
Two new recombinant guinea-pig lipocalins, Cav p 2 and Cav p 3, in the diagnosis of guinea-pig allergy.
This study identified major guinea-pig allergens and expressed them as recombinant proteins in order to define their allergenic potential and clinical importance in allergic patients. Major IgE-reactive proteins were detected in submaxillary and harderian gland extracts. Two proteins were identified and the cDNAs were cloned. The 17 kDa protein expressed in the harderian gland corresponds to the previously described Cav p 2. The 19 kDa protein, Cav p 3, is a new allergen expressed in the submaxillary gland. Recombinant Cav p 2 and Cav p 3 were recognized by IgE antibodies from 65% and 54% of guinea-pig-allergic patients, respectively. Both proteins demonstrated equivalent allergenic activity in the mediator release assays.
Evaluation of two new recombinant guinea-pig lipocalins, Cav p 2 and Cav p 3, in the diagnosis of guinea-pig allergy.
Hilger C, Swiontek K, Kler S, Diederich C, Lehners C, Vogel L, Vieths S, Hentges F.
Clin Exp Allergy 2011 Apr 25;
|
| |
|
|
|
Photo-allergic contact dermatitis caused by isoamyl p-methoxycinnamate in an 'organic' sunscreen.
Photo-allergic contact dermatitis caused by isoamyl p-methoxycinnamate in an 'organic' sunscreen.
Photo-allergic contact dermatitis caused by isoamyl p-methoxycinnamate in an 'organic' sunscreen.
Ghazavi MK, Johnston GA.
Contact Dermatitis 2011 Feb;64(2):115-116
|
| |
|
|
|
Exposures and reactions to allergens among hairdressing apprentices and matched controls.
This study estimated the degree of exposure and adverse skin reactions to chemical substances in a cohort of hairdressing apprentices, at the start of their education, as compared with a matched sample from the general population. During their first 2 weeks of training, 382 hairdressing apprentices were enrolled in this study. For comparison, the questionnaire was sent to a control group from the general population, matched on age, sex, and postal code (n = 1870).
Within the previous year, 95.2% of hairdressing apprentices and 66.9% of the control group had dyed their hair (p < 0.001); the apprentices dyed their hair, on average, 6.6 times per year, as compared with 3.7 times per year in the control group (p < 0.001). The mean age of the first hair dying among the apprentices was 12.1 years, as compared with 13.3 years for the matched control group (p < 0.001). The hairdressing apprentices reported more eczematous reactions to hair dye (p = 0.002) than the controls. Semi-permanent so-called 'black henna tattoos' had been carried out in 48.1% of the apprentices, as compared with 31.0% of the controls (p < 0.001).
Exposures and reactions to allergens among hairdressing apprentices and matched controls.
Bregnhoj A, Sosted H, Menne T, Johansen JD.
Contact Dermatitis 2011 Feb;64(2):85-89
|
| |
|
|
|
Update on the diagnosis and treatment of shellfish allergy.
"Shellfish allergy is a frequent, long-lasting, life-threatening disorder. As shellfish consumption increases, the number of allergic reactions to shellfish is expected to continue to rise as well. During the past decade, much has been learned about the allergens involved in shellfish allergy. Potential cross-reacting allergens between shellfish and other arthropods have been identified. As our knowledge of shellfish allergen improves, we will be able to develop more accurate methods of diagnosing shellfish allergy. In addition, extensive research is currently under way for the development of safer, more effective methods of managing shellfish hypersensitivity."
Update on the diagnosis and treatment of shellfish allergy.
Ayuso R.
Curr Allergy Asthma Rep 2011 Apr 15;
|
| |
|
|
|
The History of IgE
The discovery of IgE and the role of IgE-mediated inflammation gave clinical allergy a scientific backbone, and as a result, the reputation of the specialty allergy has increased considerably over the years. Allergy diagnosis was improved by assays for in vitro determination of the presence and concentration of IgE antibodies, and clinical knowledge also broadened, allowing better service for the increasing number of allergic individuals. Access to immune assays for allergens finally allowed characterization and standardization of allergen preparations used for diagnosis and allergen-specific immunotherapy. Improved basic molecular technologies have further increased our knowledge about the complex component composition of an allergen extract, introduced IgE-specific immunotherapy, and allowed the allergist to better handle even severe allergic reactions such as anaphylaxis
The History of IgE: From discovery to 2010.
Johansson SG.
Curr Allergy Asthma Rep 2011 Apr;11(2):173-177
|
| |
|
|
|
New causes of occupational asthma.
This review focused on new causative agents of occupational asthma published in 2009 and 2010. The list of causative agents of immunologically mediated occupational asthma is continuously growing, and new agents and professions are described each year. New insights gained in occupational asthma include routine evaluation of airway inflammation and identification of allergenic triggers using molecular diagnosis. A variety of novel high and low-molecular-weight agents have been shown to induce occupational asthma. Apart from the identification of the allergenic sources implicated, molecular diagnosis and detailed characterization of the culprit allergens contributes to increase our knowledge into the pathogenic mechanisms of this disorder.
New causes of occupational asthma.
Quirce S, Sastre J.
Curr Opin Allergy Clin Immunol 2011 Apr;11(2):80-85
|
| |
|
|
|
Testing for cattle allergy: modified diagnostic cutoff levels improve sensitivity.
Diagnosis of cattle-related sensitization is complicated by the variability and complexity of cattle allergen extracts. This study evaluated a modified diagnostic procedure leading to more accurate results especially in the early phase of sensitization. 27 claw trimmers with and 65 without cattle-related symptoms using two commercially available cattle allergen extracts were evaluated. A self-prepared cattle allergen mix designed to represent the full spectrum of cattle allergens from a typical agricultural workplace was tested. More than 50% of symptomatic claw trimmers were negative with commercial extracts using a cutoff point of 0.35 kU/l. In contrast, with the self-prepared cattle allergen mix, positive results were observed for almost all of them.
Testing for cattle allergy: modified diagnostic cutoff levels improve sensitivity in symptomatic claw trimmers.
Heutelbeck A, Dik N, Hallier E, Zuberbier T, Bergmann KC.
Int Arch Occup Environ Health 2011 Feb;84(2):203-210
|
| |
|
|
|
Suitability of different glycoproteins and test systems for detecting cross-reactive carbohydrate determinant-specific ige in hymenoptera venom-allergic patients.
About 75% of detected in vitro double positivity to yellow jacket and honeybee venom is ascribed to specific IgE (sIgE) directed against cross-reactive carbohydrate determinants (CCDs). The detection of CCD-sIgE may be able to assist in resolving this issue. Eighty-seven patients with confirmed hymenoptera venom allergy and venom sIgE values of >/=0.7 kU/l were investigated. Sixty-five patients showed sIgE reactivity to both yellow jacket and honeybee venom, 22 were venom mono positive and served as controls. Occurrence of CCD-sIgE was determined using bromelain, horseradish peroxidase (HRP) and MUXF(3) on system A, and ascorbic acid oxidase (AAO), bromelain and HRP on system B. Further, a reference standard for CCD-sIgE evaluation was created: CCD positivity was assumed when at least 4 of the 6 test results were positive. According to the defined reference standard, 45/65 venom double positive patients exhibited CCD-sIgE. Using system A, comparison with the reference standard revealed sensitivity and specificity values of 96 and 97%, respectively, for MUXF(3), 100 and 100%, respectively, for bromelain, and 96 and 97%, respectively, for HRP. Using system B, sensitivity and specificity was 98 and 97%, respectively, for AAO, 62 and 95%, respectively, for bromelain, and 96 and 69%, respectively, for HRP. Results of the 3 test allergens obtained with system A showed strong correlations (r = 0.932-0.976), whereas results with system B showed lower correlations (r = 0.714-0.898).
(Editor: The use of recombinant bee allergens have been shown to be of great use in teasing out the primary bee that an individual is allergic to.)
Suitability of different glycoproteins and test systems for detecting cross-reactive carbohydrate determinant-specific ige in hymenoptera venom-allergic patients.
Mertens M, Brehler R.
Int Arch Allergy Immunol 2011 Mar 29;156(1):43-50
|
| |
|
|
|
Anaphylaxis to Buckwheat in an Atopic Child: A Risk Factor for Severe Allergy to Nuts and Seeds?
Type I allergy to buckwheat is rarely seen in children. A 7-year-old boy developed a grade III anaphylactic reaction after consumption of a cake containing buckwheat flour. Prior to this incident, the boy had developed severe allergic reactions to hazelnuts and suffered from an oral allergy syndrome to poppy seed. Analysis showed sensitization to members of the 2S albumin and 11S globulin protein families in buckwheat. Cross-reactivity was found between the 11S globulins in buckwheat, poppy and hazelnut. IgE inhibition experiments indicated that the 11S globulin in buckwheat was the initial sensitizing protein. The authors conclude that 11S globulins in buckwheat have the potential to induce IgE antibodies cross-reactive with 11S globulins in other, botanically unrelated foods and may induce anaphylactic reactions.
Anaphylaxis to Buckwheat in an Atopic Child: A Risk Factor for Severe Allergy to Nuts and Seeds?
Varga EM, Kollmann D, Zach M, Bohle B.
Int Arch Allergy Immunol 2011 Mar 30;156(1):112-116
|
| |
|
|
|
Malassezia sympodialis thioredoxin-specific T cells are highly cross-reactive to human thioredoxin in atopic dermatitis.
IgE-mediated cross-reactivity between fungal antigens and human proteins has been described in patients with atopic dermatitis (AD), but it remains to be elucidated whether there is also cross-reactivity at the T-cell level. This study sought to explore cross-reactivity at the T-cell level between the fungal thioredoxin (Mala s 13) of the skin-colonizing yeast Malassezia sympodialis and its homologous human thioredoxin (hTrx). Mala s 13-specific T-cell lines (TCLs) and T-cell clones (TCCs) from the blood and skin of patients with AD sensitized to Mala s 13 and hTrx were fully cross-reactive with hTrx. In patients with AD sensitized to Malassezia species, cross-reactivity at the T-cell level to Mala s 13 and the homologous hTrx was detectable. hTrx autoreactive skin-homing T cells might be relevant for cutaneous inflammation in patients with AD
Malassezia sympodialis thioredoxin-specific T cells are highly cross-reactive to human thioredoxin in atopic dermatitis.
Balaji H, Heratizadeh A, Wichmann K, Niebuhr M, Crameri R, Scheynius A, Werfel T.
J Allergy Clin Immunol 2011 Apr 11;
|
| |
|
|
|
Estimating the economic burden of food-induced allergic reactions and anaphylaxis in the United States.
This study sought to estimate the direct medical costs and indirect costs of food-induced allergic reactions and anaphylaxis in the United States. For 2007, direct medical costs were $225 million, and indirect costs were $115 million. Office visits accounted for 52.5% of costs, and the remainder was split between emergency visits (20%), inpatient hospitalizations (11.8%), outpatient visits (3.9%), ambulance runs (3%), and epinephrine devices (8.7%). Simulations from probabilistic sensitivity analyses suggested mean direct medical costs were $307 million and indirect costs were $203 million. The economic burden of allergic reactions caused by food and anaphylaxis was an estimated half a billion dollars in 2007. Ambulatory visits accounted for more than half of the costs.
Estimating the economic burden of food-induced allergic reactions and anaphylaxis in the United States.
Patel DA, Holdford DA, Edwards E, Carroll NV.
J Allergy Clin Immunol 2011 Apr 11;
|
| |
|
|
|
Stinging insect hypersensitivity: A practice parameter update 2011.
"These parameters were developed by the Joint Task Force on Practice Parameters, representing the American Academy of Allergy, Asthma & Immunology (AAAAI); the American College of Allergy, Asthma & Immunology (ACAAI); and the Joint Council of Allergy, Asthma and Immunology. The AAAAI and the ACAAI have jointly accepted responsibility for establishing 'Stinging insect hypersensitivity: a practice parameter update II.' Because this document incorporated the efforts of many participants, no single individual, including those who served on the Joint Task Force, is authorized to provide an official AAAAI or ACAAI interpretation of these practice parameters. Any request for information about or an interpretation of these practice parameters by the AAAAI or the ACAAI should be directed to the Executive Offices of the AAAAI, the ACAAI, and the Joint Council of Allergy, Asthma and Immunology. This is a complete and comprehensive document at the current time. The medical environment is a changing environment, and not all recommendations will be appropriate for all patients. These parameters are not designed for use by pharmaceutical companies in drug promotion. The Joint Task Force understands that the cost of diagnostic tests and therapeutic agents is an important concern that may appropriately influence the work-up and treatment chosen for a given patient. The Joint Task Force recognizes that the emphasis of our primary recommendations regarding a medication may vary, for example, depending on third party payer issues and product patent expiration dates. However, since a given test or agent's cost is so widely variable, and there is a paucity of pharmacoeconomic data, the Joint Task Force generally does not consider cost when formulating Practice Parameter recommendations. In extraordinary circumstances, when the cost benefit of an intervention is prohibitive as supported by pharmacoeconomic data, commentary may be provided."
Stinging insect hypersensitivity: A practice parameter update 2011.
Golden DB, Moffitt J, Nicklas RA, Freeman T, Graft DF, Reisman RE, Tracy JM, Bernstein D, Blessing-Moore J, Cox L, Khan DA, Lang DM, Oppenheimer J, Portnoy JM, Randolph C, Schuller DE, Specto.
J Allergy Clin Immunol 2011 Apr;127(4):852-854
|
| |
|
|
|
Microarrayed recombinant allergens for diagnostic testing.
"The development of protein microarray-based immunoassays and the availability of recombinant allergens have, to a significant extent, emerged together over the past decade. Their long-anticipated wider application to allergy diagnosis has recently begun to accelerate. This review discusses some of the strengths and weaknesses of molecularly defined allergy testing and the microarray platform. Several recent applications of microarray assays to allergy testing are also summarized. Promising findings, particularly in the context of food and latex allergy, point to the potential for greater resolution between clinical reactivity and asymptomatic sensitization with this platform."
Microarrayed recombinant allergens for diagnostic testing.
Shreffler WG.
J Allergy Clin Immunol 2011 Apr;127(4):843-849
|
| |
|
|
|
Anaphylaxis during anesthesia in France: An 8-year national survey.
"The incidence of allergic reactions during anesthesia, estimated on a national basis, is higher than previously estimated. These results should be taken into account in the evaluation of the benefit-to-risk ratio of the various anesthetic techniques in individuals. The similar incidence of reactions according to sex before adolescence suggests a role for sex hormones in the increase of anaphylaxis observed in women".
2516 patients were included. A diagnosis of IgE-mediated reaction was established in 1816 cases (72.18%). The most common causes were neuromuscular blocking agents ([NMBAs]; n = 1067; 58.08%), latex (n = 361; 19.65%), and antibiotics (n = 236; 12.85%). In children, a diagnosis of IgE-mediated reactions was obtained in 122 cases (45.9%). The most common causes were latex (n = 51; 41.8%), NMBAs (n = 39; 31.97%), and antibiotics (n = 11; 9.02%)
Anaphylaxis during anesthesia in France: An 8-year national survey.
Mertes PM, Alla F, Trechot P, Auroy Y, Jougla E.
J Allergy Clin Immunol 2011 Apr 15;
|
| |
|
|
|
Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood.
This study sought to investigate whether Fel d 1-specific IgG and IgG4 antibodies modify the association between cat allergen-specific IgE and childhood wheezing. Data from 2 population-based birth cohorts (United Kingdom [UK], n = 473; Australia, n = 1336) were evaluated. Cat allergen-specific IgE (whole extract) and IgG and IgG4 antibody (purified rFel d 1) levels were evaluated and logistic regression was used to estimate the relationship between wheeze and the quantitative allergen antibody levels. rFel d 1-specific IgG but not IgG4 antibody levels significantly modified the association between cat-specific IgE and childhood wheezing, with the risk of symptoms decreasing with increasing IgG levels.
Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood.
Custovic A, Soderstrom L, Ahlstedt S, Sly PD, Simpson A, Holt PG.
J Allergy Clin Immunol 2011 Apr 12;
|
| |
|
|
|
Identification, recombinant expression, and characterization of the 100 kDa high molecular weight Hymenoptera venom allergens Api m 5 and Ves v 3.
Sequencing assigned a candidate gene to the most prominent putative high m.w. allergen Api m 5 (allergen C) in honeybee (Apis mellifera) venom and also allowed identification of its homologue Ves v 3 in yellow jacket (Vespula vulgaris) venom. Both proteins exhibit a pronounced sequence identity to human dipeptidyl peptidase IV or CD26. Both recombinant Api m 5 and Ves v 3 were recognized by specific IgE of the majority of patients even in the absence of cross-reactive carbohydrate determinants. Serologic IgE reactivity closely matched activation of human basophils by Api m 5 or Ves v 3, thus underlining their relevance in functional assays. Patient IgE reactivity together with the cellular activation demonstrates for the first time the relevance of high m.w. allergens in the context of hymenoptera venom allergy.
Identification, recombinant expression, and characterization of the 100 kDa high molecular weight Hymenoptera venom allergens Api m 5 and Ves v 3.
Blank S, Seismann H, Bockisch B, Braren I, Cifuentes L, McIntyre M, Rühl D, Ring J, Bredehorst R, Ollert MW, Grunwald T, Spillner E.
J Immunol 2010 May 1;184(9):5403-13. Epub 2010 Mar 26.
|
| |
|
|
|
Allergy to seminal fluid.
Human seminal plasma allergy (HSPA) is a rare condition but it is less rare than originally reported. It occurs in two forms: a brutal systemic anaphylactic reaction associated with regional signs (70% of the cases) or as an isolated local reaction masked as chronic vulvovaginitis or as a burning semen syndrome, the accurate etiology of which is not always recognized by gynecologists and general practitioners. New data have confirmed the efficacy of immunotherapy (60-70% in the systemic form). The existence of cross antigenicity between prostatic kallikrein (present in human sperm) and the dog allergen Can f 5, which is a dog prostatic kallikrein, has recently been reported. Reactivity to that 28ákDa molecule, which is present in dog dander extracts, is found in 25 to 70% of the sera of patients allergic to dog dander. This cross-reactivity might explain the occurrence of HSPA in some women during their first sexual intercourse.
Allergy to seminal fluid.
Tonnel AB, Schlatter J
Miscellaneous 592 2010;50(3):197-199.
|
| |
|
|
|
Exhaled nitric oxide changes in asthmatic children after drinking a caffeine-containing cola drink.
Caffeine ingestion has been associated with changes in Exhaled nitric oxide (FE(NO)) concentration in adults. The present study tested the hypothesis that ingestion of a caffeine-containing cola drink will increase FE(NO) in asthmatic children and demonstrated that ingestion of a caffeine-containing cola drink was associated with a modest and transient rise in FE(NO) which is mostly explained by increased NO production in the proximal airways. Ingestion of a caffeine-containing cola drink may result in clinically relevant acute changes in FE(NO) for children with asthma.
Changes to exhaled nitric oxide in asthmatic children after drinking a caffeine-containing cola drink.
Abuzayan I, Paraskavi U, Turner SW.
Pediatr Pulmonol 2010 Dec;45(12):1228-1232
|
| |
|
|
|
Hev b 2 and Hev b 13, two major allergens of latex allergy and latex-fruit syndrome
Hev b 2 and Hev b 13 are involved in the latex allergy and latex-fruit syndrome. Both allergens consist of ubiquitous glycoproteins widely distributed in plants, especially in fruits (banana, cherry, kiwi fruit). Hev b 2 consists of an endo-ß1,3-glucanase involved in the glucan metabolism during the fruit ripening process. Hev b 13 consists of an esterase also with a metabolic function. The high prevalence of Hev b 2 and Hev b 13 in latex allergic patients make both allergens useful for improving the diagnosis of latex allergy and latex-fruit syndrome.
Hev b 2 et Hev b 13, deux allergènes majeurs de lallergie au latex et du syndrome latex-fruits / Hev b 2 and Hev b 13, two major allergens of latex allergy and latex-fruit syndrome
A. Barre, F. Bienvenu, R. Culerrier, L. Selman, M. Campistron, C. Granier, A. Didier, J. Bienvenu, P. Rougé
Rev Fr Allergol 2011;51(3):301-305
|
| |
|
|
|
Diagnosis of IgE-reactivity by analysis of molecular components (test ISAC)
"Specific IgE-reactivities have first been implemented by the use of allergenic extracts then purified or recombinant major allergens. The frequent cross-reactivity (CR) due to vegetal and insect carbohydrate determinants has been suppressed by the use of bacteria originated recombinant allergens. CR linked to homology of amino acid sequences leads to classification of allergens, either species specific or cross-reactive ones. The micro array technology (ISAC) makes a component-resolved diagnosis possible by the analysis of 103 allergens. The assessment of this technique may be applied to different pathologies. Negative tests in eight cases of idiopathic anaphylaxis are reported. The ISAC microassay applied to atopic dermatitis shows different polysensitization profiles in 22 children compared to adults. The extensive association of aeroallergen and food allergen sensitizations is a hallmark of eosinophilic esophagitis. Another indication is to set a patient-taylored immunotherapy to pollens and mites. Present restrictions are the CR without clinical relevance (PR-10 family and tropomyosins), the poor performance of certain allergens (wheat allergens, Ana c 2, Ana o 3), the absence of allergens from the following allergenic sources: mustard, lupine, lentils, almond, walnut, buckwheat. In the near future, ISAC could be applied to epidemiological studies and to the follow-up of immunotherapies studied by specific IgG4s. Present prospects are to conduct thorough investigations about the efficiency of the currently available allergens, and to develop computerized algorithms taking into account clinical profiles and patterns of sensitization to improve the diagnosis of clinically relevant sensitization and to achieve the prediction of persistence and severity."
Diagnostic de lIgE-réactivité par analyse des composants moléculaires (test ISAC) / Diagnosis of IgE-reactivity by analysis of molecular components (test ISAC)
D.-A. Moneret-Vautrin, J. Vitte, S. Jacquenet, M. Morisset, S. Denery-Papini, J.-M. Renaudin, F. Codreanu, N. Bonardel, M.-F. Fardeaux, E. Beaudouin
Rev Fr Allergol 2011;51(2):73-83
|
| |
|
|
Allergen-, Food allergy-, Intolerance-related articles
|
|
Association of single nucleotide polymorphisms in the diamine oxidase gene with diamine oxidase serum activities. |
Maintz L, Yu CF, Rodriguez E, Baurecht H, Bieber T, Illig T, Weidinger S, Novak N.
Allergy 2011 Apr 13;
|
|
|
Pollen proteases compromise the airway epithelial barrier through degradation of transmembrane adhesion proteins and lung bioactive peptides. |
Vinhas R, Cortes L, Cardoso I, Mendes VM, Manadas B, Todo-Bom A, Pires E, Verissimo P.
Allergy 2011 Apr 11;
|
|
|
Allergic asthma to psocids, a new indoor allergen of ecological building materials. |
Perotin JM, Scherer P, Leduc V, Bouchet F, Deslee G, Lavaud F.
Allergy 2011 Apr 22;
|
|
|
Pet shop workers: exposure, sensitization, and work-related symptoms. |
Renstrom A, Olsson M, Hedren M, Johansson SG, van HM.
Allergy 2011 Apr 4;
|
|
|
Diagnosing of bakers' respiratory allergy: Is specific inhalation challenge test essential? |
Wiszniewska M, Nowakowska-Swirta E, Palczynski C, Walusiak-Skorupa J.
Allergy Asthma Proc 2011 Mar;32(2):111-118
|
|
|
Cyanobacteria: An unrecognized ubiquitous sensitizing allergen? |
Bernstein JA, Ghosh D, Levin LS, Zheng S, Carmichael W, Lummus Z, Bernstein IL.
Allergy Asthma Proc 2011 Mar;32(2):106-110
|
|
|
The predictive value of skin testing in the diagnosis of local anesthetic allergy. |
McClimon B, Rank M, Li J.
Allergy Asthma Proc 2011 Mar;32(2):95-98
|
|
|
Allergen-specific T cell quantity in blood is higher in allergic compared to nonallergic individuals. |
Ueno-Yamanouchi A, Khan FM, Serushago B, Bowen T, Lu C, Luider J, Storek J.
Allergy Asthma Clin Immunol 2011 Apr 17;7(1):6
|
|
|
Results of skin tests to assess drug-induced allergy. [French] |
Bursztejn AC, Rat AC, Trechot P, Cuny JF, Schmutz JL, Barbaud A.
Ann Dermatol Venereol 2010 Nov;137(11):688-694
|
|
|
Overview of five years of occupational dermatology: The role of atopy. [French] |
Garcon-Michel N, Paul M, Lodde B, Roguedas-Contios AM, Misery L.
Ann Dermatol Venereol 2010 Nov;137(11):681-687
|
|
|
Exposure, symptoms and airway inflammation among sewage workers. |
Heldal KK, Madso L, Huser PO, Eduard W.
Ann Agric Environ Med 2010 Dec;17(2):263-268
|
|
|
Tobacco exposure and asthma morbidity in Puerto Ricans and Mexican Americans. |
Martin MA, Sadowski LS, Moy JN, Kumar R.
Ann Allergy Asthma Immunol 2011 Apr;106(4):346-348
|
|
|
Severe allergic reaction to gluten hydrolysate without reaction to wheat. |
Pelkonen AS, Makinen-Kiljunen S, Hilvo S, Siltanen M, Makela MJ.
Ann Allergy Asthma Immunol 2011 Apr;106(4):343-344
|
|
|
Anti-allergic drug testing in an environmental challenge chamber is suitable both in and out of the relevant pollen season. |
Badorrek P, Dick M, Hecker H, Schaumann F, Sousa AR, Murdoch R, Hohlfeld JM, Krug N.
Ann Allergy Asthma Immunol 2011 Apr;106(4):336-341
|
|
|
Colonizing features of Staphylococcus aureus in early childhood atopic dermatitis and in mothers: a cross-sectional comparative study done at four kindergartens in Daegu, South Korea. |
Kim BS, Kim JY, Lim HJ, Lee WJ, Lee SJ, Kim JM, Kim MB, Jang HS, Kwon KS, Kim dW.
Ann Allergy Asthma Immunol 2011 Apr;106(4):323-329
|
|
|
Indoor particulate matter increases asthma morbidity in children with non-atopic and atopic asthma. |
McCormack MC, Breysse PN, Matsui EC, Hansel NN, Peng RD, Curtin-Brosnan J, Williams DL, Wills-Karp M, Diette GB.
Ann Allergy Asthma Immunol 2011 Apr;106(4):308-315
|
|
|
Mold and Alternaria skin test reactivity and asthma in children in Connecticut. |
Lyons TW, Wakefield DB, Cloutier MM.
Ann Allergy Asthma Immunol 2011 Apr;106(4):301-307
|
|
|
The atopy patch test: is it time to redefine its significance? |
Fuiano N, Incorvaia C.
Ann Allergy Asthma Immunol 2011 Apr;106(4):278-282
|
|
|
Specific oral tolerance induction in food allergic children: is oral desensitisation more effective than allergen avoidance?: a meta-analysis of published RCTs. |
Fisher HR, du Toit G, Lack G.
Arch Dis Child 2011 Mar;96(3):259-264
|
|
|
Throw caution to the wind instruments. |
Rackley CR, Meltzer EB.
Chest 2011 Mar;139(3):729-730
|
|
|
Biologic activity of cross-reactive carbohydrate determinants in heavy drinkers. |
Gonzalez-Quintela A, Valcarcel C, Campos J, Alonso M, Sanz ML, Vidal C.
Clin Exp Allergy 2011 May;41(5):759-761
|
|
|
Association of bronchial reactivity to occupational agents with methacholine reactivity, sputum cells and immunoglobulin E-mediated reactivity. |
Malo JL, Cardinal S, Ghezzo H, L'Archeveque J, Castellanos L, Maghni K.
Clin Exp Allergy 2011 Apr;41(4):497-504
|
|
|
Timothy grass pollen extract-induced gene expression and signalling pathways in airway epithelial cells. |
Roschmann KI, Luiten S, Jonker MJ, Breit TM, Fokkens WJ, Petersen A, van Drunen CM.
Clin Exp Allergy 2011 Apr 8;
|
|
|
The complexities of defining atopy in severe childhood asthma. |
Frith J, Fleming L, Bossley C, Ullmann N, Bush A.
Clin Exp Allergy 2011 Apr 8;
|
|
|
Basophil allergen threshold sensitivity, CD-sens, is a measure of allergen sensitivity in asthma. |
Dahlen B, Nopp A, Johansson SG, Eduards M, Skedinger M, Adedoyin J.
Clin Exp Allergy 2011 Apr 25;
|
|
|
Development and validation of a structured questionnaire for the diagnosis of oral allergy syndrome in subjects with seasonal allergic rhinitis during the UK birch pollen season. |
Skypala IJ, Calderon MA, Leeds AR, Emery P, Till SJ, Durham SR.
Clin Exp Allergy 2011 Apr 25;
|
|
|
Can Immunoglobulin E-measurement replace challenge tests in allergic rhinoconjunctivits to grass pollen? |
Huss-Marp J, Darsow U, Brockow K, Pfab F, Weichenmeier I, Schober W, Petersson CJ, Borres MP, Ring J, Behrendt H.
Clin Exp Allergy 2011 Apr 25;
|
|
|
Evaluation of two new recombinant guinea-pig lipocalins, Cav p 2 and Cav p 3, in the diagnosis of guinea-pig allergy. |
Hilger C, Swiontek K, Kler S, Diederich C, Lehners C, Vogel L, Vieths S, Hentges F.
Clin Exp Allergy 2011 Apr 25;
|
|
|
Online version of the food allergy quality of life questionnaire-adult form: validity, feasibility and cross-cultural comparison. |
Goossens NJ, Flokstra-de Blok BM, Vlieg-Boerstra BJ, Duiverman EJ, Weiss CC, Furlong TJ, Dubois AE.
Clin Exp Allergy 2011 Apr;41(4):574-581
|
|
|
Effect of anti-IgE therapy on food allergen specific T cell responses in eosinophil associated gastrointestinal disorders. |
Foster B, Foroughi S, Yin Y, Prussin C.
Clin Mol Allergy 2011 Apr 28;9(1):7
|
|
|
Quantitative assessment of diethylthiourea exposure in two cases of occupational allergic contact dermatitis. |
Friis UF, Johansen JD, Krongaard T, Menne T.
Contact Dermatitis 2011 Feb;64(2):116-118
|
|
|
Photo-allergic contact dermatitis caused by isoamyl p-methoxycinnamate in an 'organic' sunscreen. |
Ghazavi MK, Johnston GA.
Contact Dermatitis 2011 Feb;64(2):115-116
|
|
|
An outbreak of occupational allergic contact dermatitis caused by 2-N-octyl-4-isothiazolin-3-one among workers in an adhesive factory. |
Ghazavi MK, Johnston GA.
Contact Dermatitis 2011 Feb;64(2):114-115
|
|
|
Contact allergy to beryllium chloride: report of 12 cases. |
Toledo F, Silvestre JF, Cuesta L, Latorre N, Monteagudo A.
Contact Dermatitis 2011 Feb;64(2):104-109
|
|
|
Dermatological screening and results of patch testing among Polish apprentice hairdressers. |
Krecisz B, Kiec-Swierczynska M, Chomiczewska D.
Contact Dermatitis 2011 Feb;64(2):90-95
|
|
|
Exposures and reactions to allergens among hairdressing apprentices and matched controls. |
Bregnhoj A, Sosted H, Menne T, Johansen JD.
Contact Dermatitis 2011 Feb;64(2):85-89
|
|
|
Healthy worker effect in hairdressing apprentices. |
Bregnhoj A, Sosted H, Menne T, Johansen JD.
Contact Dermatitis 2011 Feb;64(2):80-84
|
|
|
Screening for Compositae sensitization with pure allergens: implications of molecular structure, strength of reaction, and time of testing. |
Paulsen E, Andersen KE.
Contact Dermatitis 2011 Feb;64(2):96-103
|
|
|
Hand dermatitis among university hospital nursing staff with or without atopic eczema: assessment of risk factors. |
Lan CC, Tu HP, Lee CH, Wu CS, Ko YC, Yu HS, Lu YW, Li WC, Chen GS.
Contact Dermatitis 2011 Feb;64(2):73-79
|
|
|
Suggested improvements for the allergenicity assessment of genetically modified plants used in foods. |
Goodman RE, Tetteh AO.
Curr Allergy Asthma Rep 2011 Apr 13;
|
|
|
Forget the worm-does the early bird avoid developing egg allergy? |
Atkins D.
Curr Allergy Asthma Rep 2011 Apr 12;
|
|
|
Are we still missing the point(s) when managing children with food-related anaphylaxis? |
Atkins D.
Curr Allergy Asthma Rep 2011 Apr 12;
|
|
|
Update on the diagnosis and treatment of shellfish allergy. |
Ayuso R.
Curr Allergy Asthma Rep 2011 Apr 15;
|
|
|
The History of IgE: From discovery to 2010. |
Johansson SG.
Curr Allergy Asthma Rep 2011 Apr;11(2):173-177
|
|
|
New causes of occupational asthma. |
Quirce S, Sastre J.
Curr Opin Allergy Clin Immunol 2011 Apr;11(2):80-85
|
|
|
Management of occupational Hymenoptera allergy. |
Rueff F, Chatelain R, Przybilla B.
Curr Opin Allergy Clin Immunol 2011 Apr;11(2):69-74
|
|
|
Pesticides and asthma. |
Hernandez AF, Parron T, Alarcon R.
Curr Opin Allergy Clin Immunol 2011 Apr;11(2):90-96
|
|
|
Testing for cattle allergy: modified diagnostic cutoff levels improve sensitivity in symptomatic claw trimmers. |
Heutelbeck A, Dik N, Hallier E, Zuberbier T, Bergmann KC.
Int Arch Occup Environ Health 2011 Feb;84(2):203-210
|
|
|
Effects of traffic air pollution and hornbeam pollen on adult asthma hospitalizations in Zagreb. |
Krmpotic D, Luzar-Stiffler V, Rakusic N, Stipic MA, Hrga I, Pavlovic M.
Int Arch Allergy Immunol 2011 Mar 29;156(1):62-68
|
|
|
Suitability of different glycoproteins and test systems for detecting cross-reactive carbohydrate determinant-specific ige in hymenoptera venom-allergic patients. |
Mertens M, Brehler R.
Int Arch Allergy Immunol 2011 Mar 29;156(1):43-50
|
|
|
Interaction of allergens, major histocompatibility complex molecules, and t cell receptors: a 'menage a trois' that opens new avenues for therapeutic intervention in type i allergy. |
Jahn-Schmid B, Pickl WF, Bohle B.
Int Arch Allergy Immunol 2011 Mar 29;156(1):27-42
|
|
|
Anaphylaxis to Buckwheat in an Atopic Child: A Risk Factor for Severe Allergy to Nuts and Seeds? |
Varga EM, Kollmann D, Zach M, Bohle B.
Int Arch Allergy Immunol 2011 Mar 30;156(1):112-116
|
|
|
Malassezia sympodialis thioredoxin-specific T cells are highly cross-reactive to human thioredoxin in atopic dermatitis. |
Balaji H, Heratizadeh A, Wichmann K, Niebuhr M, Crameri R, Scheynius A, Werfel T.
J Allergy Clin Immunol 2011 Apr 11;
|
|
|
Estimating the economic burden of food-induced allergic reactions and anaphylaxis in the United States. |
Patel DA, Holdford DA, Edwards E, Carroll NV.
J Allergy Clin Immunol 2011 Apr 11;
|
|
|
Low sensitivity of commercially available rApi m 1 for diagnosis of honeybee venom allergy. |
Korosec P, Valenta R, Mittermann I, Celesnik N, Erzen R, Zidarn M, Kosnik M.
J Allergy Clin Immunol 2011 Apr 8;
|
|
|
Recombinant allergens: What does the future hold? |
Valenta R, Niespodziana K, Focke-Tejkl M, Marth K, Huber H, Neubauer A, Niederberger V.
J Allergy Clin Immunol 2011 Apr;127(4):860-864
|
|
|
Stinging insect hypersensitivity: A practice parameter update 2011. |
Golden DB, Moffitt J, Nicklas RA, Freeman T, Graft DF, Reisman RE, Tracy JM, Bernstein D, Blessing-Moore J, Cox L, Khan DA, Lang DM, Oppenheimer J, Portnoy JM, Randolph C, Schuller DE, Specto.
J Allergy Clin Immunol 2011 Apr;127(4):852-854
|
|
|
Microarrayed recombinant allergens for diagnostic testing. |
Shreffler WG.
J Allergy Clin Immunol 2011 Apr;127(4):843-849
|
|
|
Anaphylaxis during anesthesia in France: An 8-year national survey. |
Mertes PM, Alla F, Trechot P, Auroy Y, Jougla E.
J Allergy Clin Immunol 2011 Apr 15;
|
|
|
Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood. |
Custovic A, Soderstrom L, Ahlstedt S, Sly PD, Simpson A, Holt PG.
J Allergy Clin Immunol 2011 Apr 12;
|
|
|
Hexamethylene diisocyanate asthma is associated with genetic polymorphisms of CD14, IL-13, and IL-4 receptor alpha. |
Bernstein DI, Kissling GE, Khurana HG, Yucesoy B, Johnson VJ, Cartier A, Gautrin D, Sastre J, Boulet LP, Malo JL, Quirce S, Tarlo SM, Langmeyer S, Luster MI, Lummus ZL.
J Allergy Clin Immunol 2011 Apr 11;
|
|
|
Carrier-bound, nonallergenic Ole e 1 peptides for vaccination against olive pollen allergy. |
Twaroch TE, Focke M, Civaj V, Weber M, Balic N, Mari A, Ferrara R, Quirce S, Spitzauer S, Swoboda I, Valenta R.
J Allergy Clin Immunol 2011 Apr 20;
|
|
|
Allergen exposure modifies the relation of sensitization to fraction of exhaled nitric oxide levels in children at risk for allergy and asthma. |
Sordillo JE, Webb T, Kwan D, Kamel J, Hoffman E, Milton DK, Gold DR.
J Allergy Clin Immunol 2011 Apr 2;
|
|
|
Ara h 1-reactive T cells in individuals with peanut allergy. |
Delong JH, Hetherington SK, Wambre E, James EA, Robinson D, Kwok WW.
J Allergy Clin Immunol 2011 Apr 1;
|
|
|
Sensitivity to environmental irritants and capsaicin cough reaction in patients with a positive methacholine provocation test before and after treatment with inhaled corticosteroids. |
Ekstrand Y, Ternesten-Hasseus E, Arvidsson M, Lofdahl K, Palmqvist M, Millqvist E.
J Asthma 2011 Apr 13;
|
|
|
Association between tree pollen counts and asthma ED visits in a high-density urban center. |
Jariwala SP, Kurada S, Moday H, Thanjan A, Bastone L, Khananashvili M, Fodeman J, Hudes G, Rosenstreich D.
J Asthma 2011 Apr 1;
|
|
|
Associations of age and birth cohort with total and specific IgE antibody levels. |
Tsukioka K, Toyabe S, Akazawa K.
J Asthma 2011 Apr;48(3):211-216
|
|
|
Identification, recombinant expression, and characterization of the 100 kDa high molecular weight Hymenoptera venom allergens Api m 5 and Ves v 3. |
Blank S, Seismann H, Bockisch B, Braren I, Cifuentes L, McIntyre M, Rühl D, Ring J, Bredehorst R, Ollert MW, Grunwald T, Spillner E.
J Immunol 2010 May 1;184(9):5403-13. Epub 2010 Mar 26.
|
|
|
Allergy to seminal fluid. |
Tonnel AB, Schlatter J
Miscellaneous 592 2010;50(3):197-199.
|
|
|
Changes to exhaled nitric oxide in asthmatic children after drinking a caffeine-containing cola drink. |
Abuzayan I, Paraskavi U, Turner SW.
Pediatr Pulmonol 2010 Dec;45(12):1228-1232
|
|
|
Omega-3 polyunsaturated fatty acids and bronchial inflammation in grass pollen allergy after allergen challenge. |
Kitz R, Rose MA, Schubert R, Beermann C, Kaufmann A, Bohles HJ, Schulze J, Zielen S.
Respir Med 2010 Dec;104(12):1793-1798
|
|
|
Allergic diseases in children and farming environment. [French] |
Hulin M, nnesi-Maesano I.
Rev Mal Respir 2010 Dec;27(10):1195-1220
|
|
|
Asthme professionnel induit par les irritants / Occupational asthma induced by irritants |
F. de Blay
Rev Fr Allergol 2011;51(3):315-317
|
|
|
il, paupières et allergènes de contact / Eye, eyelids and contact allergens |
E. Collet, M. Castelain, B. Milpied
Rev Fr Allergol 2011;51(3):318-322
|
|
|
Relation entre les tests cutanés, les IgE spécifiques et les tests de provocation bronchique / Relationship between skin tests, specific IgE and bronchial provocation tests |
C. Barnig, F. de Blay
Rev Fr Allergol 2011;51(3):329-331
|
|
|
Lallergie au paracétamol / Allergy to paracetamol |
L. Wémeau-Stervinou, G. Tercé, C. Bailliez, B. Wallaert
Rev Fr Allergol 2011;51(3):332-335
|
|
|
Lallergie à linsuline : mise au point / Allergy to insulin: development |
J. Waton
Rev Fr Allergol 2011;51(3):336-342
|
|
|
Le régime sans nickel a sa place dans les eczémas et la dysidrose : pour / The nickel-free diet has its place in the eczema and pompholyx : Pro |
N. Raison-Peyron
Rev Fr Allergol 2011;51(3):343-346
|
|
|
Le régime sans nickel a sa place dans les eczémas et la dysidrose : contre / The nickel-free diet has its place in the eczema and pompholyx : Con |
D. Tennstedt
Rev Fr Allergol 2011;51(3):347-349
|
|
|
Contre : les composés organiques volatils dorigine fongique ont un impact sur la santé / Con : volatile organic compounds of fungal origin have an impact on health |
G. Reboux, A.-P. Bellanger, J.-C. Dalphin
Rev Fr Allergol 2011;51(3):350-353
|
|
|
Lenquête allergologique alimentaire est systématique chez lenfant asthmatique : contre / The investigation is systematic food allergy in asthmatic children: Cons |
J. Robert
Rev Fr Allergol 2011;51(3):354-359
|
|
|
Communications orales et posters : Allergènes |
Rev Fr Allergol 2011;51(3):366-372
|
|
|
Relation entre allergènes de lenvironnement intérieur, sensibilisation et symptômes de rhinite et asthme allergiques / Relationship between indoor environmental allergens, sensitization and symptoms of allergic rhinitis and asthma |
A. Casset, J.-J. Braun
Rev Fr Allergol 2011;51(2):104-110
|
|
|
Anaphylaxie dépendante de lexercice et ingestion de figue / Exercise-dependent anaphylaxis associatiated with the ingestion of figs. |
N. Murinello, M. Hayot, C. Galera, H.-D. Donnadieu, P. Demoly
Rev Fr Allergol 2011;51(2):111-114
|
|
|
Allergie à larachide : intérêt de lapproche moléculaire. / Peanut allergy: importance of molecular approach |
M. Drouet
Rev Fr Allergol 2011;51(2):115-117
|
|
|
Analyse darticles : réactions dhypersensibilité allergique et non allergique aux venins et salives dinsectes. / Analysis articles: hypersensitivity allergic and non allergic to insect venom and saliva |
Rev Fr Allergol 2011;51(2):118-123
|
|
|
Utilisation des récepteurs de limmunité innée par les allergènes. / Use of receptors of innate immunity by allergens. |
H. Hammad
Rev Fr Allergol 2011;51(3):130-133
|
|
|
Tryptase sérique : le sommet de liceberg / Tryptase levels: the tip of the iceberg |
J. Vitte
Rev Fr Allergol 2011;51(3):183-185
|
|
|
Les allergènes moléculaires : évolution ou révolution dans le diagnostic de lallergie / Molecular allergens: evolution or revolution in the diagnosis of allergy |
J. Bienvenu, P. Rouzaire, F. Bienvenu
Rev Fr Allergol 2011;51(3):186-191
|
|
|
The basophil activation tests in drug allergy |
D. Ebo
Rev Fr Allergol 2011;51(3):192-193
|
|
|
Les bases chimiques de lallergie de contact / The chemical basis of contact allergy |
J.-P. Lepoittevin
Rev Fr Allergol 2011;51(3):208-211
|
|
|
La recherche dune allergie de contact aux produits apportés par le malade / The search for a contact allergy to products made ??by the patient |
A. Goossens
Rev Fr Allergol 2011;51(3):212-215
|
|
|
Les allergènes de contact professionnels inducteurs dasthme / Occupational contact allergens inducing asthma |
P. Frimat, S. Fantoni-Quinton
Rev Fr Allergol 2011;51(3):216-219
|
|
|
Intolérance à laspirine et mécanismes de lhypersensibilité / Intolerance to aspirin and mechanisms of hypersensitivity |
G. Devouassoux
Rev Fr Allergol 2011;51(3):220-223
|
|
|
Nouvelles perspectives dans le diagnostic de lallergie à luf / New perspectives in the diagnosis of egg allergy |
A.H. Benhamou
A.H. Benhamou
Rev Fr Allergol 2011;51(3):230-233
|
|
|
Les protocoles de tolérance à luf / The protocols of tolerance to egg |
D. de Boissieu
Rev Fr Allergol 2011;51(3):234-237
|
|
|
Vaccination et allergie à luf / Vaccination and allergy to egg |
É. Bidat
Rev Fr Allergol 2011;51(3):238-242
|
|
|
Les tests épicutanés chez les patients atteints de dermatite atopique : les atopy patch tests / Patch tests in patients with atopic dermatitis: the atopy patch test |
A. Nosbaum, A. Hennino, J.-F. Nicolas, F. Bérard
Rev Fr Allergol 2011;51(3):243-247
|
|
|
Épidémiologie de lasthme et des allergies alimentaires / Epidemiology of asthma and food allergies |
G. Dutau, F. Rancé
Rev Fr Allergol 2011;51(3):248-254
|
|
|
Allergie immédiate aux bleus et autres opacifiants / Immediate allergy to contrast media and other blue |
P.-M. Mertes, F. Hasdenteufel, M.-A. Regnier, C. Mouton-Faivre, G. Kanny, P. Trechot, J.-M. Malinovsky
Rev Fr Allergol 2011;51(3):260-264
|
|
|
Méthodes de caractérisation des extraits allergéniques / Characterization methods of allergen extracts |
T. Batard, E. Nony, H. Chabre, J. Bouley, P. Lemoine, K. Jain, M.-N. Couret, C. Berrouet, J. Barberon, A. Huet, S. Horiot, L. Mascarell, V. Bodo, P. Moingeon
Rev Fr Allergol 2011;51(3):274-277
|
|
|
Production et standardisation des extraits allergéniques en 2011 / Production and standardization of allergenic extracts in 2011 |
V. Leduc
Rev Fr Allergol 2011;51(3):278-281
|
|
|
Méthodes dobtention dun allergène recombinant / Methods for obtaining a recombinant allergens |
A. Casset
Rev Fr Allergol 2011;51(3):282-285
|
|
|
Hev b 2 et Hev b 13, deux allergènes majeurs de lallergie au latex et du syndrome latex-fruits / Hev b 2 and Hev b 13, two major allergens of latex allergy and latex-fruit syndrome |
A. Barre, F. Bienvenu, R. Culerrier, L. Selman, M. Campistron, C. Granier, A. Didier, J. Bienvenu, P. Rougé
Rev Fr Allergol 2011;51(3):301-305
|
|
|
Composants parfumés. Nouvelles sources dexposition aux allergènes de la batterie standard / Perfume components. New sources of exposure to allergens of the standard battery |
F. Giordano-Labadie
Rev Fr Allergol 2011;51(3):306-309
|
|
|
Agents de vulcanisation et conservateurs de la batterie standard : nouvelles sources dallergène / Vulcanizing agents and preservatives of the standard battery: new sources of allergen |
M. Vigan
Rev Fr Allergol 2011;51(3):310-314
|
|
|
Prevalence of sensitization to avian proteins in the adult population claiming a history of allergy to egg and wishing to be vaccinated against influenza H1N1 [French] |
C. Mailhol, K. Sedkaoui, D. Attias, A. Didier
Rev Fr Allergol 2011;51(2):95-98
|
|
|
Intérêt du dosage de la tryptase sérique aux urgences pédiatriques / Value of assay of serum tryptase in pediatric emergency |
A. Brunel, C. Sarret, A. Tridon, S. Ughetto, A. Labbé
Rev Fr Allergol 2011;51(2):99-103
|
|
|
Diagnostic de lIgE-réactivité par analyse des composants moléculaires (test ISAC) / Diagnosis of IgE-reactivity by analysis of molecular components (test ISAC) |
D.-A. Moneret-Vautrin, J. Vitte, S. Jacquenet, M. Morisset, S. Denery-Papini, J.-M. Renaudin, F. Codreanu, N. Bonardel, M.-F. Fardeaux, E. Beaudouin
Rev Fr Allergol 2011;51(2):73-83
|
|
|
Tattoo-induced vasculitis: is it really the ink? |
Kluger N.
Am J Emerg Med 2011 Mar;29(3):347
|
|
|
Type 1 and type IV hypersensitivity to nickel. |
Walsh ML, Smith VH, King CM.
Australas J Dermatol 2010 Nov;51(4):285-286
|
|
|
Elicitation of the immune response to p-phenylenediamine in allergic patients: the role of dose and exposure time. |
Goebel C, Coenraads PJ, Rothe H, Kunze G, Kock M, Schlatter H, Gerberick GF, Blomeke B.
Br J Dermatol 2010 Dec;163(6):1205-1211
|
|
|
In vivo and in vitro evaluation of the residual allergenicity of partially hydrolysed infant formulas. |
van Esch BC, Knipping K, Jeurink P, van der HS, Dubois AE, Willemsen LE, Garssen J, Knippels LM.
Toxicol Lett 2011 Mar 25;201(3):264-269
|
|
Previous Issues of Allergy Advisor Digest
January 2010
February 2010
March 2010
April 2010
May 2010
June 2010
July 2010
August 2010
September 2010
October 2010
November 2010
December 2010
January 2011
February 2011
March 2011
April 2011
May 2011
June 2011
July 2011
August 2011
September 2011
October 2011
November 2011
December 2011
January 2012
February 2012
March 2012
April 2012
May 2012
June 2012
July 2012
August 2012
September 2012
October 2012
November 2012
December 2012
January 2013
February 2013
March 2013
April 2013
| To subscribe to future Digest installments , subscribe here, and we will notify you when the new Digest is published.
|
|
