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 Allergy Advisor Digest - January 2013
Editor: Dr. Harris A. Steinman

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This is a monthly digest of interesting information that is being added to Allergy Advisor. While we add a great deal of information every month, here we highlight some of the more interesting articles.
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Read Anti-Saccharomyces cerevisiae autoantibodies in autoimmune diseases: from bread baking to autoimmunity.
Read Patch testing with the textile dyes Disperse Orange 1 and Disperse Yellow 3 and some of their potential metabolites, and simultaneous reactions to para-amino compounds.
Read Contact allergy to air-exposed geraniol
Read Bed bug saliva causes release of monocytic inflammatory mediators: plausible cause of cutaneous bite reactions.
Read Cow's milk challenge increases weakly acidic reflux in children with cow's milk allergy and gastroesophageal reflux disease.
Read Threshold dose distributions for 5 major allergenic foods in children.
Read Effect of atmospheric levels of SO2 and NO2: on allergenicity of Box elder.
Read Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.
Read Asystole after the first dose of ceftriaxone.
Read One-week oral challenge with penicillin in diagnosis of penicillin allergy.
Read Importance of serum basal tryptase levels in children with insect venom allergy.
Read Salmon allergen exposure, occupational asthma, and respiratory symptoms among salmon processing workers.
Read A case report of bell pepper anaphylaxis: Could 1, 3-beta-glucanase be the culprit allergen?
Read Anaphylaxis following cilantro (coriander) ingestion.
Read Diagnostic performance of single and multiplex IgE testing to recombinant parvalbumins in fish allergy.
Read Significance of Ara h 2 in clinical reactivity and effect of cooking methods on allergenicity.

Abstracts shared in January 2013 Advisor Digest Newsletter

Read Peamaclein - A new peach allergenic protein: similarities, differences and misleading features compared to Pru p 3.
Read Occupational contact allergy caused by rubber gloves--nothing has changed.
Read Allergic transfusion reactions in a patient with multiple food allergies.
Read A case of anaphylaxis caused by lemon sorbet
Read The diagnostic value of specific IgE to Ara h 2 to predict peanut allergy in children is comparable to a validated and updated diagnostic prediction model.
Read Tri a 36, a low molecular weight glutenin, as a novel major wheat food allergen.
Read Analysis of olive allergens.
Read Bullous reactions to bedbug bites reflect cutaneous vasculitis.
Read Identification of potential allergens involved in systemic reactions to melon and watermelon.
Read Food protein-induced enterocolitis syndrome triggered by orange juice.
Read Differences in IgE mediated basophil degranulation induced by proteic fractions from whole flea body extract in patients with papular urticaria by flea bite and healthy controls
Read Identification of a new IgE-binding epitope of peanut oleosin that cross-reacts with buckwheat.

Allergy and Intolerance Abstracts
Anti-Saccharomyces cerevisiae autoantibodies in autoimmune diseases: from bread baking to autoimmunity.
Saccharomyces cerevisiae is best known as the baker's and brewer's yeast, but its residual traces are also frequent excipients in some vaccines. Although anti-S. cerevisiae autoantibodies (ASCAs) are considered specific for Crohn's disease, a growing number of studies have detected high levels of ASCAs in patients affected with autoimmune diseases as compared with healthy controls, including antiphospholipid syndrome, systemic lupus erythematosus, type 1 diabetes mellitus, and rheumatoid arthritis. Commensal microorganisms such as Saccharomyces are required for nutrition, proper development of Peyer's aggregated lymphoid tissue, and tissue healing. However, even the commensal nonclassically pathogenic microbiota can trigger autoimmunity when fine regulation of immune tolerance does not work properly. The protein database of the National Center for Biotechnology Information (NCBI) was consulted, comparing Saccharomyces mannan to several molecules with a pathogenetic role in autoimmune diseases. Thanks to the NCBI bioinformation technology tool, several overlaps in molecular structures (50-100 %) were identified when yeast mannan, and the most common autoantigens were compared. The autoantigen U2 snRNP B'' was found to conserve a superfamily protein domain that shares 83 % of the S. cerevisiae mannan sequence. Furthermore, ASCAs may be present years before the diagnosis of some associated autoimmune diseases as they were retrospectively found in the preserved blood samples of soldiers who became affected by Crohn's disease years later. These results strongly suggest that ASCAs' role in clinical practice should be better addressed in order to evaluate their predictive or prognostic relevance.

Anti-Saccharomyces cerevisiae autoantibodies in autoimmune diseases: from bread baking to autoimmunity.  
Rinaldi M, Perricone R, Blank M, Perricone C, Shoenfeld Y.
Clin Rev Allergy Immunol 2013 Jan 5;

Index
Allergy and Intolerance Abstracts
Patch testing with the textile dyes Disperse Orange 1 and Disperse Yellow 3 and some of their potential metabolites, and simultaneous reactions to para-amino compounds.
In in vitro, human skin bacteria are able to split disperse azo dyes into the corresponding aromatic amines, some of which are sensitizers in the local lymph node assay. The authors hypothesized that the molecules of disperse dyes migrate onto the skin while garments are worn, and are metabolized and degraded by commensal skin bacteria. These molecules penetrate the skin and induce sensitization. Ten patients allergic to Disperse Yellow 3 (DY3) and/or Disperse Orange 1 (DO1) were patch tested with a dilution series of the purified dyes 4-nitroaniline and p-aminodiphenylamine in concentrations equimolar to those of purified DO1 in the dilution series, as well as 4-aminoacetanilide and 2-amino-p-cresol in concentrations equimolar to those of purified DY3 in the dilution series. Three patterns of patch test reactions could be seen. The 6 patients who were positive to DO1 and DY3 also reacted to p-aminodiphenylamine and 2-amino-p-cresol. Two patients were positive to DO1 only, and both reacted to p-aminodiphenylamine, but to neither 4-aminoacetanilide or 2-amino-p-cresol. Two patients did not react to DO1 or DY3 on this occasion. The authors conclude that it is possible that the major sensitizers in contact allergy to DO1 and DY3 are their metabolites, p-aminodiphenylamine and 2-amino-p-cresol, respectively, which might be formed by the azoreductase pathway of skin bacteria.

Patch testing with the textile dyes Disperse Orange 1 and Disperse Yellow 3 and some of their potential metabolites, and simultaneous reactions to para-amino compounds.  
Malinauskiene L, Zimerson E, Bruze M, Ryberg K, Isaksson M.
Contact Dermatitis 2012 Sep;67(3):130-140

Click to view abstract

Index
Allergy and Intolerance Abstracts
Contact allergy to air-exposed geraniol
The fragrance terpene geraniol forms sensitizing compounds via autoxidation and skin metabolism. Geranial and neral, the two isomers of citral, are the major haptens formed in both of these activation pathways. The pattern of reactions to pure and oxidized geraniol, and metabolites/autoxidation products, was studied to investigate the importance of autoxidation or cutaneous metabolism in contact allergy to geraniol. Pure and oxidized geraniol were tested at 2.0% petrolatum in 2227 and 2179 consecutive patients, respectively. In parallel, geranial, neral and citral were tested in 2152, 1626 and 1055 consecutive patients, respectively. Pure and oxidized geraniol gave positive patch test reactions in 0.13% and 0.55% of the patients, respectively. Eight of 11 patients with positive patch test reactions to oxidized geraniol also reacted to citral or its components. Relevance for the positive patch test reactions in relation to the patients' dermatitis was found in 11 of 14 cases. Therefore testing with oxidized geraniol could detect more cases of contact allergy to geraniol. The reaction pattern of the 14 cases presented indicates that both autoxidation and metabolism could be important in sensitization to geraniol.

Contact allergy to air-exposed geraniol: clinical observations and report of 14 cases.  
Hagvall L, Karlberg AT, Christensson JB.
Contact Dermatitis 2012 Jul;67(1):20-27

Click to view abstract

Index
Allergy and Intolerance Abstracts
Bed bug saliva causes release of monocytic inflammatory mediators: plausible cause of cutaneous bite reactions.
This study evauated the ability of bed bug salivary extract (SGE) to induce inflammatory reactions responsible for cutaneous manifestations and found that SGE stimulated the production of several potent chemokines and cytokines from macrophages. Chemokines induced by SGE included those known to recruit eosinophils (eotaxin), attract neutrophils [interleukin (IL)-8] or induce their survival and proliferation (granulocyte colony-stimulating factor). Cytokines involved in cell-mediated immunity, including IL-7, IL-10 and IL-12, were also induced. Saliva of bed bugs contains protein and non-protein molecules that have pleotropic effects on macrophages, orchestrating the immune response in the skin after bed bug bites.

Bed bug saliva causes release of monocytic inflammatory mediators: plausible cause of cutaneous bite reactions.  
Goddard J, Hasenkampf N, Edwards KT, de SR, Embers ME.
Int Arch Allergy Immunol 2013 Jan 23;161(2):127-130

Index
Allergy and Intolerance Abstracts
Cow's milk challenge increases weakly acidic reflux in children with cow's milk allergy and gastroesophageal reflux disease.
In children with cows milk allergy (CMA) and suspected GERD, cow's milk (CM) exposure increases the number of weakly acidic reflux episodes. CM challenge during 48-hour multichannel intraluminal impedance-pH monitoring identifies a subgroup of patients with allergen-induced reflux, and in selected cases of children with CMA in whom GERD is suspected, its use could be considered as part of diagnostic work-up

Cow's milk challenge increases weakly acidic reflux in children with cow's milk allergy and gastroesophageal reflux disease.  
Borrelli O, Mancini V, Thapar N, Giorgio V, Elawad M, Hill S, Shah N, Lindley KJ.
J Pediatr 2012 Sep;161(3):476-481

Click to view abstract

Index
Allergy and Intolerance Abstracts
Threshold dose distributions for 5 major allergenic foods in children.
For most allergenic foods, insufficient threshold dose information within the population restricts the advice on levels of unintended allergenic foods which should trigger precautionary labeling on prepackaged foods. This study wanted to derive threshold dose distributions for major allergenic foods and to elaborate the protein doses at which a proportion of the allergic population is likely to respond.

For 7 allergenic foods double-blind, placebo-controlled food challenges (DBPCFCs) with a positive outcome for allergic reactions were selected from the clinical database of children routinely tested to diagnose food allergy at the University Medical Center Groningen. For each allergen 2 population threshold distributions were determined with the individual minimal eliciting dose and the preceding dose of each DBPCFC for objective symptoms and any symptom (either subjective or objective). Individual positive DBPCFCs were available for peanut (n = 135), cow's milk (n = 93), hen's egg (n = 53), hazelnut (n = 28), and cashew nut (n = 31). Fewer children were challenged with soy (n = 10) or walnut (n = 13). Threshold dose distributions showed a good statistical and visual fit. The protein dose at which 5% of the allergic population is likely to respond with objective reactions was 1.6 mg for peanut, 1.1 mg for cow's milk, 1.5 mg for hen's egg, 7.4 mg for cashew nut, and 0.29 mg for hazelnut. Thresholds for any symptom were on average 2 to 6 times lower than for objective symptoms. The 95% upper and lower confidence intervals of the threshold distributions were overlapping. The peanut threshold distribution on objective symptoms was similar to the distribution of another European center.

Threshold dose distributions for 5 major allergenic foods in children.  
Blom WM, Vlieg-Boerstra BJ, Kruizinga AG, van der HS, Houben GF, Dubois AE.
J Allergy Clin Immunol 2013 Jan;131(1):172-179

Index
Allergy and Intolerance Abstracts
Effect of atmospheric levels of SO2 and NO2: on allergenicity of Box elder.
This study investigated the effects of SO(2) and NO(2) on the protein content, allergenicity, and germination rate of Acer negundo pollen. Protein content was lower in SO(2)-exposed pollen samples and slightly higher in NO(2)-exposed pollen compared to the control sample. No different polypeptide profiles were revealed by SDS-PAGE between exposed and nonexposed pollen, but the immunodetection assays indicated higher IgE recognition by all sera of sensitized patients to Acer negundo pollen extracts in all exposed samples in comparison to the nonexposed samples. These results indicated that in urban areas, concentrations of SO(2) and NO(2) below the limits established for human protection can indirectly aggravate pollen allergy on predisposed individuals and affect plant reproduction. (Sousa 2012 ref.28541 7)

In vitro exposure of Acer negundo pollen to atmospheric levels of SO2 and NO2: effects on allergenicity and germination.  
Sousa R, Duque L, Duarte AJ, Gomes CR, Ribeiro H, Cruz A, Esteves da Silva JC, Abreu I.
Miscellaneous Environ Sci Technol 2012 Feb 21;46(4):2406-12.

Abstract

Index
Allergy and Intolerance Abstracts
Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.
Serum albumin (SA) is the most abundant plasma protein in mammals. SA is a multifunctional protein with extraordinary ligand binding capacity, making it a transporter molecule for a diverse range of metabolites, drugs, nutrients, metals and other molecules. Due to its ligand binding properties, albumins have wide clinical, pharmaceutical, and biochemical applications. Albumins are also allergenic, and exhibit a high degree of cross-reactivity due to significant sequence and structure similarity of SAs from different organisms. Here we present crystal structures of albumins from cattle (BSA), horse (ESA) and rabbit (RSA) sera. The structural data are correlated with the results of immunological studies of SAs. We also analyze the conservation or divergence of structures and sequences of SAs in the context of their potential allergenicity and cross-reactivity. In addition, we identified a previously uncharacterized ligand binding site in the structure of RSA, and calcium binding sites in the structure of BSA, which is the first serum albumin structure to contain metal ions

Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.  
Majorek KA, Porebski PJ, Dayal A, Zimmerman MD, Jablonska K, Stewart AJ, Chruszcz M, Minor W.
Mol Immunol 2012 Oct;52(3-4):174-182

Click to view abstract

Index
Allergy and Intolerance Abstracts
Asystole after the first dose of ceftriaxone.
The incidence of ceftriaxone-related hypersensitivity skin reactions is between 1% and 3%, whereas anaphylaxis is rare. Asystole after the administration of single-dose ceftriaxone is described in a 55-year-old man who had been admitted with high fever, abdominal pain, dysuria, and weakness. An infusion of 1 g ceftriaxone was started slowly. One minute later, cardiac arrest occurred. The rhythm was asystole.

Asystole after the first dose of ceftriaxone.  
Saritas A, Erbas M, Gonen I, Candar M, Ozturk O, Kandis H, Sezen G.
Am J Emerg Med 2012 Sep;30(7):1321-1324

Click to view abstract

Index
Allergy and Intolerance Abstracts
One-week oral challenge with penicillin in diagnosis of penicillin allergy.
Many patients experience reactions during penicillin treatment. The diagnosis may be difficult and is mainly based on short-term tests. The European Network for Drug Allergy (ENDA) guidelines proposed for diagnosing penicillin allergy do not include long-term challenge. In this study a total of 405 patients were evaluated. The ENDA guidelines were extended, to include a 7-day oral treatment (p.o.7) with penicillin for all patients who were negative in the ENDA programme. Among the 405 patients; 85 had an immediate reaction to penicillin, and a further 13 reacted during p.o.7. Among the 307 patients with a negative outcome, 88 had a case history of reaction to other beta-lactam antibiotics and were subsequently tested with the culprit drug. Thirteen patients had a positive outcome: 3 on single-dose challenge and 10 during p.o.7. The extended penicillin diagnostic work-up was positive in 111 patients, 30.0% showed immediate reactions and 5.7% reacted during p.o.7. Approximately 20% of all patients with positive outcome during penicillin challenge are detected by adding p.o.7 with penicillin to the original ENDA guidelines

One-week oral challenge with penicillin in diagnosis of penicillin allergy.  
Hjortlund J, Mortz CG, Skov PS, Eller E, Poulsen JM, Borch JE, Bindslev-Jensen C.
Acta Derm Venereol 2012 May;92(3):307-312

Click to view abstract

Index
Allergy and Intolerance Abstracts
Importance of serum basal tryptase levels in children with insect venom allergy.
The aim of this study was to evaluate the serum basal tryptase (sBT) levels of venom-allergic children with varying severity of clinical reactions. Serum basal tryptase levels were estimated. Children who suffered from large local reaction (LLR) or SR after insect stings were included along with healthy control subjects without a history of any local or SR after insect stings. A total of 128 children with a median age of 8.9 years (range 3.2-17.4) were enrolled. The results indicate that sBT levels are associated with a higher risk of severe SR in children with insect venom hypersensitivity. Determination of sBT levels may help clinicians to identify patients under risk of severe SRs and optimal and timely use of therapeutic interventions in children with venom allergy

Importance of serum basal tryptase levels in children with insect venom allergy.  
Yavuz ST, Sackesen C, Sahiner UM, Buyuktiryaki B, Arik YE, Sekerel BE, Soyer OU, Tuncer A.
Allergy 2013 Jan 18;

Index
Allergy and Intolerance Abstracts
Salmon allergen exposure, occupational asthma, and respiratory symptoms among salmon processing workers.
This investigation was triggered by three cases of asthma-about 10% of the workforce-occurring in a salmon processing plant over a short period of time. Exposures to airborne salmon allergen, airborne mold spores, and endotoxin in water and air were measured during work. Using a sensitive ELISA, workers were exposed to high levels of salmon major allergen Sal s 1 at the filleting machine and at the filleting table. Airborne endotoxin levels were low, and mold levels were elevated. Only the three initial asthma cases had IgE to salmon. Of the other workers, 65% reported respiratory symptoms at work. These had lower pulmonary function than workers without such symptoms.

Salmon allergen exposure, occupational asthma, and respiratory symptoms among salmon processing workers.  
hlman-Hoglund A, Renstrom A, Larsson PH, Elsayed S, Andersson E.
Am J Ind Med 2012 Jul;55(7):624-630

Click to view abstract

Index
Allergy and Intolerance Abstracts
A case report of bell pepper anaphylaxis: Could 1, 3-beta-glucanase be the culprit allergen?
A case report of bell pepper anaphylaxis: Could 1, 3-beta-glucanase be the culprit allergen? A 34-year-old woman presented with anaphylaxis. After eating red bell pepper she immediately experienced plantar and palmer itching, urticaria, stupor, and breathing impairment. She was hypotensive and had low oxygen saturation. One month after that, she presented with a second episode of palmer and plantar itching and skin rash, immediately after eating a sauce containing crude red peppers. She reported oral allergic syndrome to peach, walnut, and chestnut and immediate urticaria when using latex gloves. SPTs with commercial extract were positive to red pepper and tomato and negative to other Solanaceae (eggplant and potato). Positive SPTs were recorded for a number of pollen plants, latex and food. Prick by prick with bell pepper was positive for red pepper and negative for green pepper. Total Ig E was 106 UI/mL. Serum speci?c IgE was positive for bell pepper (2.7 kUI/L) peach (16.6 kUI/L), peanut (10.6 kUI/L), almond (5.53 kUI/L), walnut (12.7 kUI/L), chestnut (6.21 kUI/L), and latex (15.5 kUI/L). ISAC proved sensitization to latex hevein (Hev b 6) and lipid transfer proteins (LTP) of peach (Pru p 3), mugwort (Art v 3), and hazelnut (Cor a 9). Immunoblotting showed Ig E binding bands of 30 to 35 kDa for red pepper and 10 kDa for peach. We suggest that it could be a 1,3-b-glucanase, which has been identi?ed in latex (Hev b 2, 35 kDa). It had been previously described as a cause of cross-reactivity between latex and bell pepper. (Callero 2012 ref.28520 7)

A case report of bell pepper anaphylaxis: Could 1, 3-beta-glucanase be the culprit allergen?  
Callero A, Perez E, Ledesma A, Martinez-Tadeo JA, Hernandez G, Rodriguez-Plata E, Garcia-Robaina JC.
Ann Allergy Asthma Immunol 2012 Dec;109(6):474-475

Index
Allergy and Intolerance Abstracts
Anaphylaxis following cilantro (coriander) ingestion.
Anaphylaxis following cilantro ingestion. A 52-year-old white male presented for evaluation of a systemic reaction that occurred after ingesting fresh bruschetta bread with coriander (cilantro) leaves. On the ?rst occasion, he developed diffuse urticaria that was self-limited. On the second occasion, he developed severe angioedema of the face, urticaria, and laryngeal edema with wheezing. The patient then purposely consumed the same food with minute amounts of cilantro, but quickly stopped the meal when he developed mild itching of the face with angioedema of the face and lips that did not progress. Skin prick testing with fresh cilantro leaf was negative. IgE antibody to coriander (cilantro) seed was 0.99 Ku/L.

Anaphylaxis following cilantro ingestion.  
Unkle DW, Ricketti AJ, Ricketti PA, Cleri DJ, Vernaleo JR.
Ann Allergy Asthma Immunol 2012 Dec;109(6):471-472

Index
Allergy and Intolerance Abstracts
Diagnostic performance of single and multiplex IgE testing to recombinant parvalbumins in fish allergy.
Parvalbumins of carp (Cyp c 1) and cod (Gad c 1) show an amino acid sequence identity of 68%. This study, the authors aimed to assess the performance of CAP and ISAC in the detection of sIgE to rCyp c 1 and rGad c 1 in 30 patients who reported immediate reactions and had positive skin prick tests to more than 1 ?sh species. The ?sh most commonly involved in reactions were whiff, sole, and hake. Additionally, 19 sera were tested with an ISAC microarray of 103 allergens including recombinant carp and cod parvalbumins. Most patients presented urticaria after ?sh ingestion (66.7%), followed by oral and digestive symptoms (23.3% each), bronchospasm (16.7%), and anaphylaxis (10%). All sera recognized a 12-kDa band in cod extract identi?ed as parvalbumin. All patients had positive CAP (>0.35 kU/L) to cod and whiff extracts, and positive CAP and ISAC (>0.35 ISU) to rCyp c 1 and rGad c 1. The 19 sera tested in the ISAC assay were positive to rCyp c 1 and rGad c 1. rCyp c 1 and rGad c 1 were strongly correlated, but the IgE amount to rCyp c 1 was higher. In this study, the authors have shown for the ?rst time a similar performance of rCyp c 1 and rGad c 1 on CAP and ISAC in patients allergic to ?sh.

Diagnostic performance of single and multiplex IgE testing to recombinant parvalbumins in fish allergy.  
Vazquez-Cortes S, Eguiluz G, Radauer C, Breiteneder H, Fernandez-Rivas M.
Ann Allergy Asthma Immunol 2012 Nov;109(5):362-363

Index
Allergy and Intolerance Abstracts
Significance of Ara h 2 in clinical reactivity and effect of cooking methods on allergenicity.
The prevalence and clinical severity of peanut allergy vary between Western countries and Asia. It has been suggested that cooking methods are responsible for this discrepancy. This study evaluated the specific IgE responses to major peanut allergens in peanut allergic Korean children and examined the influence of different cooking methods on peanut proteins. Raw peanut protein extracts were immunolabeled with serum samples from 42 children with a level of peanut specific IgE of 15 kUA/L or higher to detect specific binding to Ara h 1, Ara h 2, and Ara h 3. Clinical severity scores were assessed on a scale of 0 to 5. Protein extracts from boiled, roasted, fried, and pickled peanuts were analyzed with pooled serum samples from 7 patients. Most patients' serum samples reacted with Ara h 1 (76.2%) and Ara h 3 (78.6%) from raw peanuts, whereas only 53.0% of patients had specific IgE against Ara h 2. IgE binding to Ara h 2 was more prevalent in patients with more severe reaction than in those with mild reactions. IgE binding to Ara h 2 was increased by roasting, but there was significantly less IgE binding after vinegar treatment. These results suggest that Ara h 2 is an important allergen to predict clinical symptoms but less prevalent in Korean children than in Western children. This finding may be attributed in part to different cooking methods and dietary habits among regions.

Significance of Ara h 2 in clinical reactivity and effect of cooking methods on allergenicity.  
Kim J, Lee JY, Han Y, Ahn K.
Ann Allergy Asthma Immunol 2013 Jan;110(1):34-38

Index

Allergen-, Food allergy-, Intolerance-related articles

Airway inflammatory responses following exposure to occupational agents.  
Prince P, Lemiere C, Dufour MH, Chaboillez S, Boulet LP.
Chest 2012 Jun;141(6):1522-1527
Click to view abstract

Peamaclein - A new peach allergenic protein: similarities, differences and misleading features compared to Pru p 3.  
Tuppo L, Alessandri C, Pomponi D, Picone D, Tamburrini M, Ferrara R, Petriccione M, Mangone I, Palazzo P, Liso M, Giangrieco I, Crescenzo R, Bernardi ML, Zennaro D, Helmer-Citterich M, Mari .
Clin Exp Allergy 2013 Jan;43(1):128-140

In silico prediction of Ara h 2 T cell epitopes in peanut-allergic children.  
Pascal M, Konstantinou GN, Masilamani M, Lieberman J, Sampson HA.
Clin Exp Allergy 2013 Jan;43(1):116-127

Value of the clinical history in the diagnosis of urticaria/angioedema induced by NSAIDs with cross-intolerance.  
Blanca-Lopez N, Torres J, Dona I, Campo P, Rondon C, Seoane Reula ME, Salas M, Canto G, Blanca M.
Clin Exp Allergy 2013 Jan;43(1):85-91

Living with severe allergy: an anaphylaxis campaign national survey of young people.  
Worth A, Regent L, Levy M, Ledford C, East M, Sheikh A.
Clin Transl Allergy 2013 Jan 22;3(1):2

Novel approaches to food allergy.  
Yang YH, Chiang BL.
Clin Rev Allergy Immunol 2013 Jan 18;

Anti-Saccharomyces cerevisiae autoantibodies in autoimmune diseases: from bread baking to autoimmunity.  
Rinaldi M, Perricone R, Blank M, Perricone C, Shoenfeld Y.
Clin Rev Allergy Immunol 2013 Jan 5;

Contact allergy to epoxy resin: risk occupations and consequences.  
Bangsgaard N, Thyssen JP, Menne T, Andersen KE, Mortz CG, Paulsen E, Sommerlund M, Veien NK, Laurberg G, Kaaber K, Thormann J, Andersen BL, Danielsen A, Avnstorp C, Kristensen B, Kristensen .
Contact Dermatitis 2012 Aug;67(2):73-77
Click to view abstract

Current patch test results with the European baseline series and extensions to it from the 'European Surveillance System on Contact Allergy' network, 2007-2008.  
Uter W, Aberer W, rmario-Hita JC, Fernandez-Vozmediano JM, Ayala F, Balato A, Bauer A, Ballmer-Weber B, Beliauskiene A, Fortina AB, Bircher A, Brasch J, Chowdhury MM, Coenraads PJ, Schuttel.
Contact Dermatitis 2012 Jul;67(1):9-19
Click to view abstract

Contact sensitization to tree moss (Evernia furfuracea extract, INCI) is heterogeneous.  
Uter W, Schmidt E, Lessmann H, Schnuch A.
Contact Dermatitis 2012 Jul;67(1):36-41
Click to view abstract

Sodium tetrachloropalladate for diagnosing palladium sensitization.  
Muris J, Kleverlaan CJ, Rustemeyer T, von Blomberg ME, van H, Feilzer AJ, Scheper RJ.
Contact Dermatitis 2012 Aug;67(2):94-100
Click to view abstract

Patch testing with own cosmetics-- prospective study of testing and reporting of adverse effects to the Swedish Medical Products Agency.  
Tammela M, Lindberg M, Isaksson M, Inerot A, Rudel J, Berne B.
Contact Dermatitis 2012 Jul;67(1):42-46
Click to view abstract

The role of the skin irritation response in polysensitization to fragrances.  
Nagtegaal MJ, Pentinga SE, Kuik J, Kezic S, Rustemeyer T.
Contact Dermatitis 2012 Jul;67(1):28-35
Click to view abstract

Targeted testing with diethylthiourea often reveals clinically relevant allergic contact dermatitis caused by neoprene rubber.  
Dall AB, Andersen KE, Mortz CG.
Contact Dermatitis 2012 Aug;67(2):89-93
Click to view abstract

Occupational contact allergy to monomeric isocyanates.  
alto-Korte K, Suuronen K, Kuuliala O, Henriks-Eckerman ML, Jolanki R.
Contact Dermatitis 2012 Aug;67(2):78-88
Click to view abstract

Epoxy pipe relining - an emerging contact allergy risk for workers.  
Anveden B, Lind ML, Liden C.
Contact Dermatitis 2012 Aug;67(2):59-65
Click to view abstract

High frequency of false-positive reactions in attempted patch testing with acrylate/methacrylate mixes.  
Goon AT, Bruze M, Zimerson E, Goossens A, Goh CL, Isaksson M.
Contact Dermatitis 2012 Sep;67(3):157-161
Click to view abstract

Hand eczema: prevalence and risk factors of hand eczema in a population of 2274 healthcare workers.  
Ibler KS, Jemec GB, Flyvholm MA, Diepgen TL, Jensen A, Agner T.
Contact Dermatitis 2012 Oct;67(4):200-207
Click to view abstract

Patch testing with the textile dyes Disperse Orange 1 and Disperse Yellow 3 and some of their potential metabolites, and simultaneous reactions to para-amino compounds.  
Malinauskiene L, Zimerson E, Bruze M, Ryberg K, Isaksson M.
Contact Dermatitis 2012 Sep;67(3):130-140
Click to view abstract

Establishing aluminium contact allergy.  
Siemund I, Zimerson E, Hindsen M, Bruze M.
Contact Dermatitis 2012 Sep;67(3):162-170
Click to view abstract

Skin exposure to epoxy in the pipe relining trade - an observational study.  
Fillenham G, Liden C, Anveden B.
Contact Dermatitis 2012 Aug;67(2):66-72
Click to view abstract

Allergic contact dermatitis caused by a skin-lightening agent, 5,5'-dipropylbiphenyl-2,2'-diol. A comment.  
Roberts DW, Aptula AO.
Contact Dermatitis 2012 Jun;66(6):357-359

Allergic contact dermatitis caused by Hedera helix arborescens and not by Hedera helix L.  
Lurquin E, Swinnen I, Goossens A.
Contact Dermatitis 2012 Jun;66(6):352-353

Allergic contact dermatitis caused by methylisothiazolinone from a 'waist reduction belt'.  
Uter W, Uter M, Steen-Schuberth B, Schnuch A.
Contact Dermatitis 2012 Jun;66(6):347-348

Occupational contact allergy caused by benzidine in three tannery workers.  
Febriana SA, Jungbauer F, Soebono H, Coenraads PJ.
Contact Dermatitis 2012 Jun;66(6):345-346

A case of occupational airborne allergic contact dermatitis caused by faveira amargosa, a tropical timber.  
Kop EN, van Ginkel CJ, Rockmann H, van d.
Contact Dermatitis 2012 Jun;66(6):344-345

Presumed primary contact sensitization to methylisothiazolinone from paint: a chemical that became airborne.  
Kaae J, Menne T, Thyssen JP.
Contact Dermatitis 2012 Jun;66(6):341-342

Urticarial allergic contact dermatitis caused by UV-cured printing ink.  
Higgins E, Collins P.
Contact Dermatitis 2012 Jun;66(6):340-341

Swimming pool contact dermatitis caused by 1-bromo-3-chloro-5,5-dimethyl hydantoin.  
Dalmau G, Martinez-Escala ME, Gazquez V, Pujol-Montcusi JA, Canadell L, Espona QM, Pujol RM, Vilaplana J, Gaig P, Gimenez-Arnau A.
Contact Dermatitis 2012 Jun;66(6):335-339
Click to view abstract

Anaphylaxis and severe systemic reactions caused by skin contact with persulfates in hair-bleaching products.  
Hoekstra M, van der HS, Coenraads PJ, Schuttelaar ML.
Contact Dermatitis 2012 Jun;66(6):317-322
Click to view abstract

Hair dye sensitivity testing: a critical commentary.  
Orton D, Basketter D.
Contact Dermatitis 2012 Jun;66(6):312-316
Click to view abstract

Self-testing for contact sensitization to hair dyes--scientific considerations and clinical concerns of an industry-led screening programme.  
Thyssen JP, Sosted H, Uter W, Schnuch A, Gimenez-Arnau AM, Vigan M, Rustemeyer T, Granum B, McFadden J, White JM, White IR, Goossens A, Menne T, Liden C, Johansen JD.
Contact Dermatitis 2012 Jun;66(6):300-311
Click to view abstract

Self-testing for contact sensitization to hair dyes.  
Goossens A.
Contact Dermatitis 2012 Jun;66(6):299

Methylchloroisothiazolinone/methylisothiazolinone contact sensitization: diverging trends in subgroups of IVDK patients in a period of 19 years.  
Uter W, Gefeller O, Geier J, Schnuch A.
Contact Dermatitis 2012 Sep;67(3):125-129
Click to view abstract

A case of systemic allergic dermatitis caused by inhaled budesonide: cross-reactivity in patch tests with the novel inhaled corticosteroid ciclesonide.  
Salava A, Alanko K, Hyry H.
Contact Dermatitis 2012 Oct;67(4):244-246

Allergic contact dermatitis caused by neem oil.  
Greenblatt DT, Banerjee P, White JM.
Contact Dermatitis 2012 Oct;67(4):242-243

Allergic contact dermatitis caused by octocrylene in a young child.  
Dumon D, Dekeuleneer V, Tennstedt D, Goossens A, Baeck M.
Contact Dermatitis 2012 Oct;67(4):240-242

Systemic allergic dermatitis of the lips resulting from allergy to an antimicrobial agent in a contact lens disinfecting solution.  
Cressey BD, Scheinman PL.
Contact Dermatitis 2012 Oct;67(4):239-240

Allergic contact dermatitis to methyl hydroxystearate in a rubber respirator.  
Benton EC, White IR, McFadden JP.
Contact Dermatitis 2012 Oct;67(4):238-239

Occupationally induced fixed drug eruption caused by a non-steroidal anti-inflammatory agent.  
Lamchahab F, Baeck M.
Contact Dermatitis 2012 Sep;67(3):176-177

A patient's drawing helped the physician to make the correct diagnosis: occupational contact allergy to isothiazolinone.  
Friis UF, Menne T, Thyssen JP, Johansen JD.
Contact Dermatitis 2012 Sep;67(3):174-176

Undisclosed methyldibromo glutaronitrile causing allergic contact dermatitis in a NSAID cream.  
Amaro C, Cravo M, Fernandes C, Santos R, Goncalo M.
Contact Dermatitis 2012 Sep;67(3):173-174

Contact urticaria caused by a fish-derived elastin-containing cosmetic cream.  
Nishida K, Tateishi C, Tsuruta D, Shimauchi T, Ito T, Hirakawa S, Tokura Y.
Contact Dermatitis 2012 Sep;67(3):171-172

Occupational contact allergy to a Phalaenopsis orchid cultivar.  
Andersen SL, Poulsen AG, Paulsen E.
Contact Dermatitis 2012 Aug;67(2):116-118

Contact sensitization to dittany of Crete (Origanum dictamnus) in a herbal remedy.  
Paulsen E, Wanat-Krzak M, Dall AB, Andersen KE.
Contact Dermatitis 2012 Aug;67(2):114-116

Variability in patch test reactivity over time, falsely indicating patch test sensitization, in a patient tested with palladium salts.  
Engfeldt M, Tillman C, Hindsen M, Bruze M.
Contact Dermatitis 2012 Aug;67(2):109-111

Airborne allergic contact dermatitis in a parquet fitter.  
Geier J, Krautheim A, Fuchs T.
Contact Dermatitis 2012 Aug;67(2):106-108

Allergic contact dermatitis caused by polyester-8 (Polycrylene(R)) in a sunscreen moisturizer.  
Esdaile B, Cooper SM.
Contact Dermatitis 2012 Aug;67(2):105-106

Allergic nickel dermatitis caused by playing the guitar: case report and assessment of nickel release from guitar strings.  
Friis UF, Menne T, Jellesen MS, Moller P, Verdingovas V, Jensen TR, Thyssen JP, Johansen JD.
Contact Dermatitis 2012 Aug;67(2):101-103

Occupational contact allergy caused by rubber gloves--nothing has changed.  
Geier J, Lessmann H, Mahler V, Pohrt U, Uter W, Schnuch A.
Contact Dermatitis 2012 Sep;67(3):149-156
Click to view abstract

Are allergenic disperse dyes used for dyeing textiles?  
Malinauskiene L, Zimerson E, Bruze M, Ryberg K, Isaksson M.
Contact Dermatitis 2012 Sep;67(3):141-148
Click to view abstract

Allergic contact dermatitis caused by isocyanates in resin jewellery.  
Nguyen R, Lee A.
Contact Dermatitis 2012 Jul;67(1):56-57

Severe immediate hypersensitivity and allergic contact dermatitis caused by hair dyes.  
Nosbaum A, Dupin C, Nicolas JF, Berard F.
Contact Dermatitis 2012 Jul;67(1):52-53

Prevalence of allergic contact dermatitis caused by hydroxyisohexyl 3-cyclohexene carboxaldehyde has not changed in Denmark.  
Heisterberg MV, Laurberg G, Veien NK, Menne T, Avnstorp C, Kaaber K, Andersen KE, Sommerlund M, Danielsen A, Andersen BL, Kristensen B, Kristensen O, Nielsen NH, Thormann J, Vissing S, Johan.
Contact Dermatitis 2012 Jul;67(1):49-51

Is hydroxyisohexyl 3-cyclohexene carboxaldehyde sensitization declining in central Europe?  
Schnuch A, Geier J, Uter W.
Contact Dermatitis 2012 Jul;67(1):47-49

Contact allergy to air-exposed geraniol: clinical observations and report of 14 cases.  
Hagvall L, Karlberg AT, Christensson JB.
Contact Dermatitis 2012 Jul;67(1):20-27
Click to view abstract

Diagnostic patch testing--does it have a wider relevance?  
Basketter DA, White IR.
Contact Dermatitis 2012 Jul;67(1):1-2

Recent advances in occupational dermatitis.  
Holness DL.
Curr Opin Allergy Clin Immunol 2013 Jan 15;

Non-IgE-mediated and irritant-induced work-related rhinitis.  
Siracusa A, Folletti I, Moscato G.
Curr Opin Allergy Clin Immunol 2013 Jan 15;

Cells and mediators in diisocyanate-induced occupational asthma.  
Shin YS, Kim MA, Pham LD, Park HS.
Curr Opin Allergy Clin Immunol 2013 Jan 15;

Phototoxic and photoallergic potential of tazarotene foam 0.1% in 2 phase 1 patch studies.  
Hogan DJ, Saenz AB.
Cutis 2012 Nov;90(5):266-271
Click to view abstract

Allergic contact dermatitis and cosmetics.  
Watkins S, Zippin J.
Cutis 2012 Oct;90(4):201-204
Click to view abstract

Five cases of contact dermatitis to a trendy pet.  
Amsler E, Bayrou O, Pecquet C, Frances C.
Dermatology 2012;224(4):292-294
Click to view abstract

Contact photoallergy to isothipendyl chlorhydrate.  
Bibas N, Sartor V, Bulai LC, Bagheri H, Nougue J, Giordano-Labadie F, Maza A, Paul C, Chouini-Lalanne N, Marguery MC.
Dermatology 2012;224(4):289-291
Click to view abstract

Phototoxic drug reaction - the dark side of summer. [German]  
Bruhn C.
Dtsch Med Wochenschr 2012 Jul;137(27):22

Allergic transfusion reactions in a patient with multiple food allergies. [German]  
Strobel E, Schoniger M, Munz M, Hiefinger-Schindlbeck R.
Dtsch Med Wochenschr 2012 Jul;137(28-29):1465-1467
Click to view abstract

Iodine allergy. [German]  
Weinstabl A, Amann PM, Wurpts G, Merk HF.
Hautarzt 2012 May;63(5):360-363
Click to view abstract

Inventory of the chemicals and the exposure of the workers' skin to these at two leather factories in Indonesia.  
Febriana SA, Jungbauer F, Soebono H, Coenraads PJ.
Int Arch Occup Environ Health 2012 Jul;85(5):517-526
Click to view abstract

Mild improvement in symptoms and pulmonary function in a long-term follow-up of patients with toluene diisocyanate-induced asthma.  
Talini D, Novelli F, Bacci E, Costa F, Dente FL, Di FA, Malagrino L, Vagaggini B, Paggiaro P.
Int Arch Allergy Immunol 2013 Jan 23;161(2):189-194

Bed bug saliva causes release of monocytic inflammatory mediators: plausible cause of cutaneous bite reactions.  
Goddard J, Hasenkampf N, Edwards KT, de SR, Embers ME.
Int Arch Allergy Immunol 2013 Jan 23;161(2):127-130

Intractable chronic pruritus as the only manifestation of IgE hypersensitivity to Anisakis.  
Gallo R, Cecchi F, Parodi A.
J Am Acad Dermatol 2012 Dec;67(6):e261

Nickel allergy and dermatitis following use of a laptop computer.  
Jensen P, Jellesen MS, Moller P, Frankild S, Johansen JD, Menne T, Thyssen JP.
J Am Acad Dermatol 2012 Oct;67(4):e170-e171

Clinical variability of shiitake dermatitis.  
Adler MJ, Larsen WG.
J Am Acad Dermatol 2012 Oct;67(4):e140-e141

Cow's milk challenge increases weakly acidic reflux in children with cow's milk allergy and gastroesophageal reflux disease.  
Borrelli O, Mancini V, Thapar N, Giorgio V, Elawad M, Hill S, Shah N, Lindley KJ.
J Pediatr 2012 Sep;161(3):476-481
Click to view abstract

Natural course and risk factors for persistence of IgE-mediated cow's milk allergy.  
Elizur A, Rajuan N, Goldberg MR, Leshno M, Cohen A, Katz Y.
J Pediatr 2012 Sep;161(3):482-487
Click to view abstract

Onychomadesis secondary to penicillin allergy in a child.  
Shah RK, Uddin M, Fatunde OJ.
J Pediatr 2012 Jul;161(1):166

A case of anaphylaxis caused by lemon sorbet.  
Akiko Naruse, Junko Osako, Daisuke Tsuruta, Shigeto Yanagihara, Masamitsu Ishii and Hiromi Kobayashi
J Aller Ther 2012;3(1):112
Click to view abstract Click to view abstract

Absence of homogenization might explain the benefits of raw cow's milk.  
Miller JD.
J Allergy Clin Immunol 2013 Jan 12;

Initial description of pork-cat syndrome in the United States.  
Posthumus J, James HR, Lane CJ, Matos LA, Platts-Mills TA, Commins SP.
J Allergy Clin Immunol 2013 Jan 23;

Atopic sensitization in the first year of life.  
Depner M, Ege MJ, Genuneit J, Pekkanen J, Roponen M, Hirvonen MR, Dalphin JC, Kaulek V, Krauss-Etschmann S, Riedler J, Braun-Fahrlander C, Roduit C, Lauener R, Pfefferle PI, Weber J, von Mut.
J Allergy Clin Immunol 2013 Jan 16;

Allergy to sulfonamides.  
Schnyder B, Pichler WJ.
J Allergy Clin Immunol 2013 Jan;131(1):256-257

Can we produce true tolerance in patients with food allergy?  
Berin MC, Mayer L.
J Allergy Clin Immunol 2013 Jan;131(1):14-22

The changing CARE for patients with food allergy.  
Jones SM, Burks AW.
J Allergy Clin Immunol 2013 Jan;131(1):3-11

Blockade of peanut allergy with a novel Ara h 2-Fcgamma fusion protein in mice.  
Liu Y, Sun Y, Chang LJ, Li N, Li H, Yu Y, Bryce PJ, Grammer LC, Schleimer RP, Zhu D.
J Allergy Clin Immunol 2013 Jan;131(1):213-221

Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2012.  
Sicherer SH, Leung DY.
J Allergy Clin Immunol 2013 Jan;131(1):55-66

The effect of provision of an adrenaline autoinjector on quality of life in children with food allergy.  
Pinczower GD, Bertalli NA, Bussmann N, Hamidon M, Allen KJ, Dunngalvin A, Hourihane JO, Gurrin LC, Tang ML.
J Allergy Clin Immunol 2013 Jan;131(1):238-240

Threshold dose distributions for 5 major allergenic foods in children.  
Blom WM, Vlieg-Boerstra BJ, Kruizinga AG, van der HS, Houben GF, Dubois AE.
J Allergy Clin Immunol 2013 Jan;131(1):172-179

The diagnostic value of specific IgE to Ara h 2 to predict peanut allergy in children is comparable to a validated and updated diagnostic prediction model.  
Klemans RJ, Otte D, Knol M, Knol EF, Meijer Y, Gmelig-Meyling FH, Bruijnzeel-Koomen CA, Knulst AC, Pasmans SG.
J Allergy Clin Immunol 2013 Jan;131(1):157-163

Peach allergy in China: A dominant role for mugwort pollen lipid transfer protein as a primary sensitizer.  
Gao ZS, Yang ZW, Wu SD, Wang HY, Liu ML, Mao WL, Wang J, Gadermaier G, Ferreira F, Zheng M, van RR.
J Allergy Clin Immunol 2013 Jan;131(1):224-226

Respiratory symptoms and respiratory-related absence from work among health care workers in Sweden.  
Kim JL, Toren K, Lohman S, Ekerljung L, Lotvall J, Lundback B, Andersson E.
J Asthma 2013 Jan 7;

Molecular and immunological characterization of Tri a 36, a low molecular weight glutenin, as a novel major wheat food allergen.  
Baar A, Pahr S, Constantin C, Scheiblhofer S, Thalhamer J, Giavi S, Papadopoulos NG, Ebner C, Mari A, Vrtala S, Valenta R.
J Immunol 2012 Sep 15;189(6):3018-3025
Click to view abstract

Suspected anaphylactic reaction associated with microemulsion propofol during anesthesia induction.  
Lee SJ, Kim SI, Jung BI, Lee SM, Kim MG, Park SY, Kim SH, Ok SY.
J Korean Med Sci 2012 Jul;27(7):827-829
Click to view abstract

Anaphylaxis to an ondansetron wafer.  
Tan J, Mehr S.
J Paediatr Child Health 2012 Jun;48(6):543-544

Heparin-induced skin lesions.  
Schindewolf M, Lindhoff-Last E, Ludwig RJ, Boehncke WH.
Lancet 2012 Nov 24;380(9856):1867-1879
Click to view abstract

Severe drug-induced hypersensitivity syndrome with a shared HLA-B allele.  
Harding DJ, Subramaniam K, MacQuillan G, Davis J, Nolan D.
Med J Aust 2012 Oct 1;197(7):411-413

Occupational diseases due to allergic and toxic chemicals in health care workers: fitness for work. [Italian]  
Crippa M, Bartolucci GB, Toffoletto F, Marcer G.
Med Lav 2012 May;103(3):187-197
Click to view abstract

In vitro exposure of Acer negundo pollen to atmospheric levels of SO2 and NO2: effects on allergenicity and germination.  
Sousa R, Duque L, Duarte AJ, Gomes CR, Ribeiro H, Cruz A, Esteves da Silva JC, Abreu I.
Miscellaneous Environ Sci Technol 2012 Feb 21;46(4):2406-12.
Abstract

Analysis of olive allergens.  
Esteve C, Montealegre C, Marina ML, GarcĂ­a MC.
Miscellaneous 592 2012 Apr 15;92:1-14.
Abstract

Structural and immunologic characterization of bovine, horse, and rabbit serum albumins.  
Majorek KA, Porebski PJ, Dayal A, Zimmerman MD, Jablonska K, Stewart AJ, Chruszcz M, Minor W.
Mol Immunol 2012 Oct;52(3-4):174-182
Click to view abstract

IgE epitopes of intact and digested Ara h 1: a comparative study in humans and rats.  
Bogh KL, Nielsen H, Madsen CB, Mills EN, Rigby N, Eiwegger T, Szepfalusi Z, Roggen EL.
Mol Immunol 2012 Jul;51(3-4):337-346
Click to view abstract

Images in clinical medicine. Anaphylaxis associated with blue dye.  
Gil-Moreno A, Perez-Benavente A.
N Engl J Med 2012 Nov 22;367(21):2026

Swimming pool attendance and respiratory symptoms and allergies among Dutch children.  
Jacobs JH, Fuertes E, Krop EJ, Spithoven J, Tromp P, Heederik DJ.
Occup Environ Med 2012 Nov;69(11):823-830
Click to view abstract

Occupational allergic contact dermatitis to acrylic fingernails in beauticians.  
Patruno C, Ayala F, Napolitano M, Bianca D, Balato N.
Occup Environ Med 2012 Oct;69(10):772

Evaluating interventions aimed at reducing occupational exposure to latex and rubber glove allergens.  
Turner S, McNamee R, Agius R, Wilkinson SM, Carder M, Stocks SJ.
Occup Environ Med 2012 Dec;69(12):925-931
Click to view abstract

Occupational exposure to cleaning products and asthma in hospital workers.  
Dumas O, Donnay C, Heederik DJ, Hery M, Choudat D, Kauffmann F, Le MN.
Occup Environ Med 2012 Dec;69(12):883-889
Click to view abstract

Maternal smoking during pregnancy, prematurity and recurrent wheezing in early childhood.  
Robison RG, Kumar R, Arguelles LM, Hong X, Wang G, Apollon S, Bonzagni A, Ortiz K, Pearson C, Pongracic JA, Wang X.
Pediatr Pulmonol 2012 Jul;47(7):666-673
Click to view abstract

Allergic reactions to foods in preschool-aged children in a prospective observational food allergy study.  
Fleischer DM, Perry TT, Atkins D, Wood RA, Burks AW, Jones SM, Henning AK, Stablein D, Sampson HA, Sicherer SH.
Pediatrics 2012 Jul;130(1):e25-e32
Click to view abstract

Farmer's lung antigens in Germany. [German]  
Sennekamp J, Joest M, Sander I, Engelhart S, Raulf-Heimsoth M.
Pneumologie 2012 May;66(5):297-301
Click to view abstract

Hypersensitivity pneumonitis with bat droppings presenting as organizing pneumonia. [French]  
Cadelis G, Rossigneux E, Tourres R.
Rev Mal Respir 2012 May;29(5):734-736

Phadiatop testing in assessing predisposition to respiratory tract symptoms of allergic origin in athletes.  
de Waard AH, Peters EM.
S Afr Med J 2012 May;102(5):309-311
Click to view abstract

Asystole after the first dose of ceftriaxone.  
Saritas A, Erbas M, Gonen I, Candar M, Ozturk O, Kandis H, Sezen G.
Am J Emerg Med 2012 Sep;30(7):1321-1324
Click to view abstract

Prasugrel-induced rash.  
Deshmukh AJ, Pant S, Cook J, Sachdeva R, Rutlen D, Uretsky BF.
Ann Pharmacother 2012 Jul;46(7-8):1123-1125

Immediate hypersensitivity reaction induced by metronidazole.  
Seto K, Knowles SR, Weber EA.
Ann Pharmacother 2012 May;46(5):763-764

Occupational exposure to laboratory animals causing a severe exacerbation of atopic eczema.  
Bhabha FK, Nixon R.
Australas J Dermatol 2012 May;53(2):155-156
Click to view abstract

The relevance of patch testing in peristomal dermatitis.  
Al-Niaimi F, Beck M, Almaani N, Samarasinghe V, Williams J, Lyon C.
Br J Dermatol 2012 Jul;167(1):103-109
Click to view abstract

Exposure to second-hand smoke and reproductive outcomes depending on maternal asthma.  
Sunyer J, Garcia-Esteban R, Castilla AM, Aurrekoetxea JJ, Iniguez C, Tardon A, Espada M, Lertxundi A, Chatzi L, Rebagliato M, Kogevinas M.
Eur Respir J 2012 Aug;40(2):371-376
Click to view abstract

Costs of childhood asthma due to traffic-related pollution in two California communities.  
Brandt SJ, Perez L, Kunzli N, Lurmann F, McConnell R.
Eur Respir J 2012 Aug;40(2):363-370
Click to view abstract

The association between tobacco and the risk of asthma, rhinoconjunctivitis and eczema in children and adolescents: analyses from Phase Three of the ISAAC programme.  
Mitchell EA, Beasley R, Keil U, Montefort S, Odhiambo J.
Thorax 2012 Nov;67(11):941-949
Click to view abstract

Indication for adrenalin autoinjector after anaphylaxis. [Danish]  
Malling HJ, Hansen KS, Mosbech H.
Ugeskr Laeger 2012 Jun 18;174(25):1741-1743
Click to view abstract

Allergic contact dermatitis caused by metals in blackboard chalk: a case report.  
Corazza M, Zauli S, Pagnoni A, Virgili A.
Acta Derm Venereol 2012 Jul;92(4):436-437

One-week oral challenge with penicillin in diagnosis of penicillin allergy.  
Hjortlund J, Mortz CG, Skov PS, Eller E, Poulsen JM, Borch JE, Bindslev-Jensen C.
Acta Derm Venereol 2012 May;92(3):307-312
Click to view abstract

Toxic epidermal necrolysis following allergic contact dermatitis caused by occupational exposure to ultraviolet-cured inks.  
Ido T, Kiyohara T, Takahashi H, Yamaguchi Y, Tani D, Kumakiri M.
Acta Derm Venereol 2012 May;92(3):313-315
Click to view abstract

Bronchial allergen challenges: doubling or quadrupling dose steps?  
Mousalli S, van K, Merget R.
Adv Exp Med Biol 2013;75585-88
Click to view abstract

Occupational non-immediate type allergic asthma due to ammonium persulfate.  
Polychronakis I, Thanasias E, Raulf-Heimsoth M, Merget R.
Adv Exp Med Biol 2013;75579-84
Click to view abstract

Occupational immediate-type allergic asthma due to potassium tetrachloroplatinate in production of cytotoxic drugs.  
Thanasias E, Polychronakis I, van K, Bruning T, Merget R.
Adv Exp Med Biol 2013;75547-53
Click to view abstract

Non-immediate, severe hypersensitivity reaction to iopamidol with cross reactivity to different radiocontrast agents.  
Makris M, Koulouris S, Katoulis A, Tyligada E, Rigopoulos D.
Allergol Int 2013 Jan 25;

The major allergen of the Parietaria pollen contains an LPS-binding region with immuno-modulatory activity.  
Bonura A, Corinti S, Schiavi E, Giacomazza D, Gianguzza F, Di FG, Colombo P.
Allergy 2013 Jan 18;

Paediatric oral peanut challenges: a comparison of practice in London and Western Switzerland.  
Ludman S, Wassenberg J, Du TG, Fox AT, Lack G, Eigenmann PA.
Allergy 2013 Jan 25;

Air pollution interacts with past episodes of bronchiolitis in the development of asthma.  
Kim BJ, Seo JH, Jung YH, Kim HY, Kwon JW, Kim HB, Lee SY, Park KS, Yu J, Kim HC, Leem JH, Lee JY, Sakong J, Kim SY, Lee CG, Kang DM, Ha M, Hong YC, Kwon HJ, Hong SJ.
Allergy 2013 Jan 25;

Importance of serum basal tryptase levels in children with insect venom allergy.  
Yavuz ST, Sackesen C, Sahiner UM, Buyuktiryaki B, Arik YE, Sekerel BE, Soyer OU, Tuncer A.
Allergy 2013 Jan 18;

Allergic anaphylaxis due to subcutaneously injected heparin.  
Anders D, Trautmann A.
Allergy Asthma Clin Immunol 2013 Jan 10;9(1):1

Salmon allergen exposure, occupational asthma, and respiratory symptoms among salmon processing workers.  
hlman-Hoglund A, Renstrom A, Larsson PH, Elsayed S, Andersson E.
Am J Ind Med 2012 Jul;55(7):624-630
Click to view abstract

Bespoke latex allergen testing improves assessment of respiratory symptoms in textile-braiding workers.  
Harris-Roberts J, Tate P, Robinson E, Griffin P, Mason H, Barber C, Curran AD, Fishwick D.
Am J Ind Med 2012 Jul;55(7):616-623
Click to view abstract

Occupational rhinitis and asthma due to EDTA-containing detergents or disinfectants.  
Laborde-Casterot H, Villa AF, Rosenberg N, Dupont P, Lee HM, Garnier R.
Am J Ind Med 2012 Aug;55(8):677-682
Click to view abstract

Bullous reactions to bedbug bites reflect cutaneous vasculitis.  
deShazo RD, Feldlaufer MF, Mihm MC, Goddard J.
Am J Med 2012 Jul;125(7):688-694
Click to view abstract

Laryngeal hypersensitivity in the World Trade Center-exposed population: the role for respiratory retraining.  
McCabe D, Altman KW.
Am J Respir Crit Care Med 2012 Sep 1;186(5):402-403
Click to view abstract

Hypersensitivity pneumonitis: insights in diagnosis and pathobiology.  
Selman M, Pardo A, King TE.
Am J Respir Crit Care Med 2012 Aug 15;186(4):314-324
Click to view abstract

AGR2 is induced in asthma and promotes allergen-induced mucin overproduction.  
Schroeder BW, Verhaeghe C, Park SW, Nguyenvu LT, Huang X, Zhen G, Erle DJ.
Am J Respir Cell Mol Biol 2012 Aug;47(2):178-185
Click to view abstract

Airborne indoor particles from schools are more toxic than outdoor particles.  
Oeder S, Jorres RA, Weichenmeier I, Pusch G, Schober W, Pfab F, Behrendt H, Schierl R, Kronseder A, Nowak D, Dietrich S, Fernandez-Caldas E, Lintelmann J, Zimmermann R, Lang R, Mages J, Fromm.
Am J Respir Cell Mol Biol 2012 Nov;47(5):575-582
Click to view abstract

Hypersensitivity to topical steroids. [French]  
Biver-Dalle C, Guichard A, Vigan M, Humbert P, Aubin F.
Ann Dermatol Venereol 2012 Jun;139(6-7):489-499

Methotrexate-induced cutaneous reactions: two case reports. [French]  
Al MM, Cosnes A, Ortonne N, Valeyrie-Allanore L.
Ann Dermatol Venereol 2012 Jun;139(6-7):472-476
Click to view abstract

Perianal ulcerations with telaprevir. [French]  
Awwad A, Renard P, Pouzoulet J, Sigal ML, Mahe E.
Ann Dermatol Venereol 2012 May;139(5):391-392

Does hypersensitivity to multiple drugs really exist?. [French]  
Studer M, Waton J, Bursztejn AC, imone-Gastin I, Schmutz JL, Barbaud A.
Ann Dermatol Venereol 2012 May;139(5):375-380
Click to view abstract

Delayed-type hypersensitivity to heparin: diagnosis and therapeutic management. [French]  
Nosbaum A, Pralong P, Rozieres A, Dargaud Y, Nicolas JF, Berard F.
Ann Dermatol Venereol 2012 May;139(5):363-368
Click to view abstract

Skin toxicity related to Percutalgine((R)): analysis of the French pharmacovigilance database. [French]  
Remy C, Barbaud A, Lebrun-Vignes B, Perrot JL, Beyens MN, Mounier G, Marsille F, Roy M, Mismetti P, Guy C.
Ann Dermatol Venereol 2012 May;139(5):350-354
Click to view abstract

Occupational exposure to airborne fungi in two Croatian sawmills and atopy in exposed workers.  
Klaric MS, Varnai VM, Calusic AL, Macan J.
Ann Agric Environ Med 2012;19(2):213-219
Click to view abstract

Identification of potential allergens involved in systemic reactions to melon and watermelon.  
Gonzalez-Mancebo E, Lopez-Torrejon G, Gonzalez de OD, Santos S, Gandolfo-Cano M, Melendez A, Salcedo G, Cuesta-Herranz J, Vivanco F, Pastor-Vargas C.
Ann Allergy Asthma Immunol 2010 Mar;104(3):271-272

A case report of bell pepper anaphylaxis: Could 1, 3-beta-glucanase be the culprit allergen?  
Callero A, Perez E, Ledesma A, Martinez-Tadeo JA, Hernandez G, Rodriguez-Plata E, Garcia-Robaina JC.
Ann Allergy Asthma Immunol 2012 Dec;109(6):474-475

Food protein-induced enterocolitis syndrome triggered by orange juice.  
Federly TJ, Ryan P, Dinakar C.
Ann Allergy Asthma Immunol 2012 Dec;109(6):472-473

Anaphylaxis following cilantro ingestion.  
Unkle DW, Ricketti AJ, Ricketti PA, Cleri DJ, Vernaleo JR.
Ann Allergy Asthma Immunol 2012 Dec;109(6):471-472

Diagnostic performance of single and multiplex IgE testing to recombinant parvalbumins in fish allergy.  
Vazquez-Cortes S, Eguiluz G, Radauer C, Breiteneder H, Fernandez-Rivas M.
Ann Allergy Asthma Immunol 2012 Nov;109(5):362-363

Glucoamylase is a potential allergen in products expressed in Neurospora crassa.  
Khurana T, Collison M, Le HB, Cambareri E, Slater JE.
Ann Allergy Asthma Immunol 2013 Feb;110(2):124-125

Wheat-dependent exercise-induced anaphylaxis in elderly patients.  
Perez-Rangel I, Gonzalo-Garijo MA, Perez-Calderon R, Zambonino MA, Corrales-Vargas SI.
Ann Allergy Asthma Immunol 2013 Feb;110(2):121-123

A case of DRESS syndrome induced by the antituberculosis drugs, prothionamide, and para-aminosalycilic acid.  
Kim JH, Jang SH, Kim DH, Park S, Kim DG, Jung KS.
Ann Allergy Asthma Immunol 2013 Feb;110(2):118-119

Anaphylaxis in a tertiary adult allergy clinic: a retrospective review of 516 patients.  
Gelincik A, Demirturk M, Yilmaz E, Ertek B, Erdogdu D, Colakoglu B, Buyukozturk S.
Ann Allergy Asthma Immunol 2013 Feb;110(2):96-100

Adverse reactions during drug challenges: a single US institution's experience.  
Kao L, Rajan J, Roy L, Kavosh E, Khan DA.
Ann Allergy Asthma Immunol 2013 Feb;110(2):86-91

Allergen of the month-fringed sagebrush.  
Weber RW.
Ann Allergy Asthma Immunol 2013 Jan;110(1):A13

Fixed drug eruption due to amoxicillin and quinolones.  
Ponce Guevara LV, Yges EL, Gracia Bara MT, Gonzalez Ruiz AM, Rodilla EM.
Ann Allergy Asthma Immunol 2013 Jan;110(1):61-62

Anaphylaxis to quinoa.  
Hong J, Convers K, Reeves N, Temprano J.
Ann Allergy Asthma Immunol 2013 Jan;110(1):60-61

Food allergy exposures among hospitalized pediatric patients.  
Franxman TJ, Strothman KR, Sublett JL, Montgomery VL, Baptist AP.
Ann Allergy Asthma Immunol 2013 Jan;110(1):56-57

Significance of Ara h 2 in clinical reactivity and effect of cooking methods on allergenicity.  
Kim J, Lee JY, Han Y, Ahn K.
Ann Allergy Asthma Immunol 2013 Jan;110(1):34-38

The identification of potentially pathogenic and therapeutic epitopes from common human allergens.  
Schulten V, Oseroff C, Alam R, Broide D, Vijayanand P, Peters B, Sette A.
Ann Allergy Asthma Immunol 2013 Jan;110(1):7-10

Treating patients with multiple drug allergies.  
Khan DA.
Ann Allergy Asthma Immunol 2013 Jan;110(1):2-6

Aquagenic Urticaria in Twins.  
Kai AC and Flohr C.
WAO Journal 2013;6(1):2
Click to view abstract Click to view abstract

Cutaneous toxic effects associated with vemurafenib and inhibition of the BRAF pathway.  
Huang V, Hepper D, Anadkat M, Cornelius L.
Arch Dermatol 2012 May;148(5):628-633
Click to view abstract

The effect of patch testing on surgical practices and outcomes in orthopedic patients with metal implants.  
Atanaskova MN, Tellez A, Molina L, Honari G, Sood A, Barsoum W, Taylor JS.
Arch Dermatol 2012 Jun;148(6):687-693
Click to view abstract

Telaprevir-induced pityriasis rubra pilaris-like drug eruption.  
Stalling SS, Vu JR, English JC.
Arch Dermatol 2012 Oct;148(10):1215-1217

Silicone injection masquerading as HIV-psoriasiform dermatosis.  
Alfalasi AA, Khalfan HG, Abdullgaffar B, Almualla A.
Arch Dermatol 2012 Oct;148(10):1212-1213

Eczematous drug eruption after ustekinumab treatment.  
Pernet C, Guillot B, Bessis D.
Arch Dermatol 2012 Aug;148(8):959-960

Anaphylaxis as an adverse event following immunisation in the UK and Ireland.  
Erlewyn-Lajeunesse M, Hunt LP, Heath PT, Finn A.
Arch Dis Child 2012 Jun;97(6):487-490
Click to view abstract

Safety in numbers: anaphylaxis risk in childhood immunisation.  
Collinson A.
Arch Dis Child 2012 Jun;97(6):485-486

Evaluation of petri dish sampling for assessment of airborne dust mite allergen in Japan. [Japanese]  
Saito A, Tsurikisawa N, Oshikata C, Nakazawa T, Yasueda H, Akiyama K.
Arerugi 2012 Nov;61(11):1657-1664

Identification of a new IgE-binding epitope of peanut oleosin that cross-reacts with buckwheat.  
Kobayashi S, Katsuyama S, Wagatsuma T, Okada S, Tanabe S.
Biosci Biotechnol Biochem 2012;76(6):1182-1188
Click to view abstract


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