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  Substance Info: (and synonyms)
Phoma betae / herbarum

Background Info:

Phoma is a very common soil fungus attacking weak or damaged plants. It is frequently isolated from different soils, dead plant tissues and potato. Phoma is frequently found indoors as a contaminator of humid surfaces, especially in connection with biodeterioration of painted walls, producing coloured spots, often pink of purple, several centimetres in diameter.

 

Adverse Reactions:

IMMUNE REACTIONS


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Buisseret found that in patients with seasonal or summer asthma, 10% proved to be allergic to fungal spores, especially Alternaria and Phoma. In a study of IgE antibodies in samples from American patients, hypersensitivity to Phonza was the second most common. (Karlsson 1989 ref.6458 7)

Reference:
Karlsson-BorgÄ A, Jonsson P, Rolfsen W. Specific IgE antibodies to 16 widespread mold genera in patients with suspected mold allergy.. Ann Allergy 1989;63:521-526



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In a study in Sao Paulo, Brazil, evaluating sensitisation in 201 patients with asthma and/or allergic rhinitis to 42 airborne fungi using skin specific IgE tests, 15 were shown to be sensitised to Alternaria, 15 to Aspergillus, 23 to Aureobasidium, 37 to Candida, 15 to Chaetomium, 19 to Epicoccum, 17 to Mucor, 20 to Phoma, 19 to Trichoderma, and 14 to Rhizopus. . (Mohovic 1988 ref.11297 5)

Reference:
Mohovic J, Gambale W, Croce J. Cutaneous positivity in patients with respiratory allergies to 42 allergenic extracts of airborne fungi isolated in Sao Paulo, Brazil. Allergol Immunopathol (Madr) 1988;16(6):397-402




Non-Immune reactions


[ 1 ]

Phaeohyphomycosis is a mycotic disease caused by dematiaceous fungi that produce brown yeast-like cells, pseudohyphae, and irregular true hyphae in tissues. Seven Korean cases of subcutaneous phaeohyphomycosis have been reported to date, ranging in age from 9-84 years. Causative organisms of subcutaneous phaeohyphomycosis were 3 of Exophiala jeanselmei, 2 of E. dermatitidis, 1 of Drechslera dematioidea and 1 of Phoma sp. Four cases of abscess and 3 cases of verrucous plaque were present as skin lesions, and were all exposed areas of the body. (Suh 2005 ref.25667 5)

Reference:
Suh MK. Phaeohyphomycosis in Korea. Nippon Ishinkin Gakkai Zasshi 2005;46(2):67-70.




OCCUPATIONAL EXPOSURE


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Allergy Advisor - Zing Solutions
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Allergy Advisor  - Food Additive and Preservative Allergy and Intolerance Database


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