Common name for edible fruit and of particular vines. European grape has been used for food since prehistoric times. Widely cultivated, many species and varieties. Red, green or purplish fruit which is smooth-skinned and fleshy. Eaten raw or dried (see Currants), and used extensively in wine making.
Fewer than a dozen varieties are grown for table grapes, the majority (90%) accounting for wine production.
Polyphenols and tannins present in red grapes may cause migraines. Main problem with grapes is contaminants on skin.
Source of potassium.
Vit v 1
Three allergens have been identified, a 30 kd, a 24 kd and a 9 kd allergen.
The 9kd allergen appears to be a LTP highly homologous to the peach LTP (80%) (Pravettoni 2001 ref.4047 8)
Specific immunoglobulin E (IgE) antibodies in the patient's serum against a 94,000 molecular-weight antigenic band was isolated. (Rodriguez 2001 ref.4717 5)
See also: Vine Pollen.
Grape allergy may be specific to a certain grape variety with tolerance to others. (Bircher 1999 ref.4124 7) Patients may not tolerate any grape species, wine or raisins. (Giannoccaro 1999 ref.2756 0)
Thaumatin-like proteins and chitinases, which are pathogenesis-related (PR) proteins, were the major soluble protein components of grapes from five cultivars of Vitis vinifera. This dominance of PR proteins was apparent at berry softening (veraison) and then throughout berry development for the Muscat of Alexandria, Sultana, and Shiraz cultivars and in the berries of the Sauvignon Blanc and Pinot Noir cultivars examined at commercial maturity. The vines in the study were irrigated and showed no obvious signs of disease. (Pocock 2000 re.4721 3)
In 11 patients with severe allergy reactions to grape and 3 with anaphylactic reactions to wine, the major allergens were an endochitinase 4A and a lipid-transfer protein (LTP) that was homologous to and cross-reactive with peach LTP. A 24-kd protein homologous to the cherry thaumatin-like allergen was a minor allergen. Endochitinase 4A is very likely the allergen in vino novello and in vino Fragolino. (Pastorello 2003 ref.7409 2)
IGE AND IMMUNE:
Allergic reactions. Anaphylaxis. (Buchbinder 1983 ref.530 72) (David 1984 ref.530 82) Cough. Pharyngealpruritis and pruritis with exercise. Bronchospasm with exercise. Urticaria. Atopic dermatitis. Flushing. Nasal symptoms. Wheezing with exercise. Oral Allergy Syndrome (Giannoccaro 1998 ref.2756 8)
This study reports a case of a 5-year-old child who suffered an oral allergy syndrome and lip angiedema after eating grapes. (Rodriguez 2001 ref.4717 7)
Allergic rhinitis and asthma (Romano 2000 ref.4809 7)
This study reports on 11 patients presenting with anaphylactic reactions following grape. The reported symptoms were: anaphylactic shock in 4 cases, of which 2 following grape ingestion and 2 following young wine consumption, severe asthma in 1 case, glottic oedema and angioedema in 4 cases, glottis oedema and urticaria in 2 cases, gastrointestinal symptoms and hypotension in 1 case. In 2 cases symptoms followed exercise. (Pravettoni 2001 ref.4047 0)
Food-dependant exercise-induced anaphylaxis. (Kidd 1983 ref.332 14) (Sheffer 1984 ref.6603 3)
Immediate hypersensitivity described in 3 patients, after the ingestion of fresh grapes. Positive skin prick test and specific IgE determination. (Anton 1997 ref.4896 3)
This study reports on a case of a 5-year-old child who suffered an oral allergy syndrome and lip angieodema after eating grapes. (Rodriquez 2001 ref.4717 7)
Exercise-induced anaphylaxis (Senna 2001 ref.4720 7)
This study reports on 11 patients with severe allergy reactions to grape and 3 with anaphylactic reactions to wine. (Pastorello 2003 ref.7409 2)
Occupational hayfever due to grape pollen. (Tsukioka 1984 ref.2045 3)
Reactions can also occur to the chemicals or additives present, including histamine.
Information supplied from an abridged section of:
Allergy Advisor - Zing Solutions
© zingsolutions.com 1998