AllAllergy.Net
Advertisement
  Substance Info: (and synonyms)
Lepidoglyphus destructor (Storage mite)

Background Info:

See Storage mites, and other species.
A non-pyroglyphid mite species.

This mite is associated with hay.

In a Canadian study, L. destructor was the most common storage mite, especially from spring to fall. It feeds on Alternaria and Penicillium.

 

Adverse Reactions:

IMMUNE REACTIONS


[ 1 / 6 ]

Clinical data obtained from these authors first 30 patients with Pancake Syndrome (Oral Mite Anaphylaxis). The majority of subjects were adolescents and young adults although OMA can occur in children. Sources include pancakes, pizza, sponge cake, pasta, cornmeal cake, bread, cheese, Parmigiana steak (prepared with contaminated grated bread), alfajor and white sauce.
Other foods have also been found to induce OMA, including beignets, "okonomi-yaki" (bonito and mackerel covered with flour), commeal cakes made with a commercial mix containing wheat and corn flour, and polenta. Other foods that can be contaminated with mites when stored for long periods at room temperature are cheese, ham, chorizo, and salami.
Reaction time was from 10 to 240 mins.Clinical manifestations were breathlessness, facial and laryngeal angioedema, wheezing, and other upper and lower respiratory tract symptoms being the most common. 2 deaths were secondary to the ingestion of mite-contaminated foods.
Symptoms No. Patients (%)
Breathlessness 27 (90)
Angioedema 15(50)
Wheezing 12 (40)
Rhinorrhea 9(30)
Cough 8 (26.6)
Stridor 6(20)
Dysphagia 6(20)
Urticaria 6(20)
Abdominal cramps 4(13.3)
Conjunctivitis 3(10)
Skin rash 2 (6.6)
Dysphonia 2 (6.6)
Sneezing 1 (3.3)
Vomiting 1 (3.3)
Cyanosis 1 (3.3)
Pruritus 1 (3.3)
Tachycardia 1 (3.3)
(Sanchez-Borges 2009 ref.23477 9)

Different mite species are present in the flours producing OMA. Among them are house dust mites (Dermatophagoides pteronyssinus and Dermatophagoides farinae), and storage mites such as Suidasia spp., Aleuroglyphus ovatus, Lepidoglyphus destructor, Tyrophagus putrescentiae, Thyreophagus entomophagus, Blomia tropicalis, and Blomia freemani. (Sanchez-Borges 2009 ref.23477 9)

Reference:
Sanchez-Borges M, Suarez-Chacon R, Capriles-Hulett A, Caballero-Fonseca F, Iraola V, Fernandez-Caldas E. Pancake Syndrome (Oral Mite Anaphylaxis). WAO Journal 2009;2(5):91-96



[ 2 / 6 ]

Isolated chronic conjunctivitis due to storage mite allergy.

Patient 1:
A 22-year-old man allergic to nuts complained of severe conjunctivitis that occurred daily on awakening for the last 5 years. Photophobia was so annoying that the patient switched to a night shift and avoided most social activities. Skin tests performed with a battery of mite extracts and common local pollens, allergenic fungi, and cat and dog danders were negative results, except for L destructor and doubtful results for G domesticus. A double-blind conjunctival provocation test with L destructor and D pteronyssinus extracts was strongly positive for L destructor and negative for D pteronyssinus. Specific IgE to L destructor was 0.47 kU/L. Changes in the bedroom resulted in resolution of symptoms.

Patient 2:
A 23-year-old man complained of daily bilateral conjunctival itching, tearing, and red eyes for 6 months. He described his office as a wet, closed basement room. Skin tests with the previously mentioned allergens produced positive results for L destructor only. A double-blind conjunctival test result was positive for L destructor. Specific IgE was 0.86 kU/L. Avoidance measures at home had little effect, and the patient received specific immunotherapy. Immunoblots of both patients’ sera samples demonstrated a single 14-kDa IgE-binding band, probably Lep d 2.1 (Garcia-Ortega 2006 ref.14086 5)

Reference:
Garcia-Ortega P, Corominas M, Iraola V, Fernandez-Caldas E. Isolated chronic conjunctivitis due to storage mite allergy. Ann Allergy Asthma Immunol 2006 May;96(5):754-755



[ 3 / 6 ]

In a random urban population of Reykjavik, Iceland, 6.3% showed IgE-mediated allergy to L. destructor. These were often polysensitized atopics with a high prevalence of clinical symptoms associated with exposure to hay. (Gislason 1999 ref.4754 1)

Reference:
Gislason D, Gislason T. IgE-mediated allergy to Lepidoglyphus destructor in an urban population - an epidemiologic study. Allergy 1999;54(8):878-83



[ 4 / 6 ]

A grain worker who had immediate nasal and conjunctival symptoms and late-phase asthmatic reactions after handling stored grain. (Garces 1991 ref.7969 3)

Reference:
Garces Sotillos M, Blanco Carmona J, Juste Picon S. Late asthma caused by inhalation of Lepidoglyphus destructor. Ann Allergy 1991;67(2 Pt 1):126-8



[ 5 / 6 ]

The dust mite Lepidoglyphus destructor is a major source of mite allergy in European rural environments, but it also causes allergy in urban populations around the world.

Reference:
Editor Comment Editorial comment, common knowledge, or still to add - -



[ 6 / 6 ]

See: Storage mite, for overview

See also other Storage mites:
Glycyphagus domesticus (Storage mite)
Lepidoglyphus destructor (Storage mite)
Tyrophagus putrescens (storage mite)
Blomia kulagini (Storage mite)
Aleuroglyphus ovatus (Storage Mite)
Caloglyphus berlesei (Storage mite)
Blomia tjibodas (Storage mite)
Blomia freemani (Storage mite)
Acarus siro (storage mite)
Blomia tropicalis (Storage mite)

Reference:
Editor Comment Editorial comment, common knowledge, or still to add - -




Occupational reactions


[ 1 ]

Storage mites (SM) are important allergen sources in the working environment of German farms. 29 samples of dust from ten henhouses were analysed. House dust mites (HDM) in both high abundance and steadiness were found. 92.1% of all mites found were domestic mites (DM = HDM + SM), whereby 52.3% of the DM found belonged to the HDM. 13 DM species (ten SM, three HDM) could be identified. 24/29 samples contained 2,452 HDM and 2,237 SM (= 4,689 DM in 24 g of dust). Summarizing abundance and steadiness showed the followings ranking: Lepidoglyphus destructor > Dermatophagoides farinae > Dermatophagoides pteronyssinus > Euroglyphus longior > Thyreophagus entomophagus > Glycyphagus domesticus > Acarus siro > Tyrophagus longior > Tyrophagus palmarum > Acarus immobilis > Glycyphagus geniculatus > Acarus farris > Gohieria fusca. (Franz 2010 ref.24791 5)

Reference:
Franz J-T, Müsken H. House dust mites as an allergen source in henhouse Allergo J 2010;1:106-



[ 2 ]

Arthropods are a documented cause of occupational allergy in cereal stores. In a Czech study, 514 grain storage units were surveyed for pest composition and density. Mites constituted the largest group of collected pests (92%) followed by psocids (5%), beetles (3%) and moths (0%). 60% of mites belonged to known allergen producing species; the most abundant were Acarus siro, A. faris, Tyrophagus putrescentiae and Lepidoglyphus destructor. This study suggests that mites represent, due to their allergenic potential, density and frequency, the most serious source of allergens in stored grain in CZ. (Stejskal 2008 ref.22438 6)

Reference:
Stejskal V, Hubert J. Risk of occupational allergy to stored grain arthropods and false pest-risk perception in Czech grain stores. Ann Agric Environ Med 2008 Jun;15(1):29-35



[ 3 ]

Occupational asthma in a poultry farmer. (Borghetti 2002 ref.7910 1)

Reference:
Borghetti C, Magarolas R, Badorrey I, Radon K, Morera J, Monso E. Sensitization and occupational asthma in poultry workers. [Spanish] Med Clin (Barc) 2002;118(7):251-5



[ 4 ]

Occupational asthma in a grain worker.a grain worker
sensitized to Lepidoglyphus destructor (Ld), who suffered from
mild asthma at the workplace. (Alvarez 1999 ref.5565 1)

Reference:
Alvarez MJ, Castillo R, Rey A, Ortega N, Blanco C, Carrillo T. Occupational asthma in a grain worker due to Lepidoglyphus destructor, assessed by bronchial provocation test and induced sputum. Allergy 1999;54(8):884-9



[ 5 ]

In 4379 patients residing in an area of cereal industries in Spain, the prevalence of mite sensitization in the total sample studied was 18.96%. The prevalence of sensitization to storage mites among mite-sensitive patients was 11.88%. Among 50 selected patients the most frequent sensitization was that to Dermatophagoides pteronyssinus (58%), followed by Dermatophagoides farinae (48%), Lepidoglyphus destructor and Tyrophagus putrescentiae (38%), Blomia kulagini (34%), and Acarus siro and Chortoglyphus arcuatus (24%). In addition, 22% of the patients presented negative prick tests and RAST for Dermatophagoides species with positive test to storage mites. Fifty percent of the 50 patients were sensitizated to Tenebrio molitor, and 36% to Blatta orientalis. (Armentia 1997 ref.7942 1)

Reference:
Armentia A, Martinez A, Castrodeza R, Martinez J, Jimeno A, Mendez J, Stolle R. Occupational allergic disease in cereal workers by stored grain pests. J Asthma 1997;34(5):369-78



[ 6 ]

In 2,578 Swedish farmers, 6.2% were found to have an allergy to storage mites. The storage mite Lepidoglyphus destructor has been identified by both RAST and bronchial challenges as a significant cause of occupational asthma in rural environments. (Van Hage-Hamsten 1994 ref.7956 3)

Reference:
van Hage-Hamsten M, Harfast B, Johansson SG. Dust mite allergy: an important cause of respiratory disease in farmers. Am J Ind Med 1994;25(1):47-8



[ 7 ]

Allergy Mixes had been introduced to screen IgE-mediated allergy among farmers: PAX 1 (horse dander, cow dander, and chicken and
goose feathers), PAX 2 (Lepidoglyphus destructor, Acarus siro (storage mites), Sitophilus granarius, and Gasterophilus intestinalis), and PAX 3 (wheat pollen, rye pollen, Aspergillus, and Alternaria). Of 440 farmers, 91 were positive to Phadiatop and 97 to any of PAX 1-3. None of the farmers were positive in all tests. Only 70/97 sera positive in RAST to PAX 1-3 had a positive Phadiatop, whereas of 91 sera positive in Phadiatop, 70 had specific IgE antibodies to PAX 1-3. The value of using either Phadiatop or PAX 1-3 is limited (sensitivity 74-79%), but, together, these four tests will detect almost all (95.9%) farmers with IgE-mediated sensitization and all (100%) with symptoms. Twenty-nine of the 440 farmers were positive in RAST to G. intestinalis, and six to S. granarius. The calculated overall prevalences of a positive RAST to G. inteslinalis and S. granarius in the whole farming population (n= 2578) of Gotland were 5.2% and 1.1% respectively. However, L. destructor gave a higher prevalence of a positive RAST than did G. intestinalis or S. granarius. (van Hage-Hamsten 1993 ref.14072 8)

Reference:
van Hage-Hamsten M, Johansson SG. In vitro diagnosis of farmers' IgE-mediated allergy by Phadiatop and three new multiallergen RAST analyses. Allergy 1993 Jul;48(5):345-8.



[ 8 ]

Occupational allergy due to hypersensitivity to cereal flours is relatively common among bakers and grain-store workers. Storage mites can contaminate wheat flour and could be an important cause of allergic symptoms due to inhalation. In 43 patients with sensitization to wheat flour, cosensitization to Lepidoglyphus destructor was found in 30%. Of these, 23% did not have a relationship with any bakery or agriculture. (Armentia 1992 ref.679 21)

Reference:
Armentia A, Tapias J, Barber D, Martin J. Sensitization to the storage mite Lepidoglyphus destructor in wheat flour respiratory allergy. Ann Allergy 1992;68:398-403



[ 9 ]

On the island of Gotland, Sweden, 5 genera of storage mites were detected on 16 farms but the different mite species were not represented on all farms. L. destructor was the dominating species on 13 of 16 farms. The authors earlier studies showed that L. destructor was the most important allergen causing symptoms from both upper and lower airways among farmers. (van Hage-Hamsten 1991 ref.8074 1)

Reference:
van Hage-Hamsten M, Johansson E, Wiren A, Johansson SG. Storage mites dominate the fauna in Swedish barn dust. Allergy 1991;46(2):142-6



[ 10 ]

The atmospheric barn air was sampled in ten barns near Cooperstown, NY and six barns near Rochester, MN, and, allergens of Aspergillus fumigatus, Thermoactinomyces vulgaris, Micropolyspori faeni, short ragweed, rye grass group I pollen, Alternaria (Alt-1), Dermatophagoides sp. Lepidoglyphus destructor, common insect allergen, mouse urine, rat urine, and cattle epithelium were measured. The most abundant allergen found in air of barns, near Rochester, USA, was Aspergillus fumigatus followed by Lepidoglyphus destructor. (Campbell 1989 ref.6322 0)

Reference:
Campbell AR, Swanson MC, Fernandez-Caldas E, Reed CE, May JJ, Pratt DS. Aeroallergens in dairy barns near Cooperstown, New York and Rochester, Minnesota. Am Rev Respir Dis 1989;140(2):317-20



[ 11 ]

RAST-positive sera were obtained from fifty-three farmers who were positive to at least one of the four storage mites (Lepidoglyphus destructor, Glycyphagus domesticus, Tyrophagus putrescentiae and Acarus siro). Sera from twelve of these farmers, eight of whom were also positive to D. pteronyssinus, were investigated with the RAST inhibition technique.(See Cross-reactivity for results) (van Hage-Hamsten 1987 ref.8084 3)

Reference:
van Hage-Hamsten M, Johansson SG, Johansson E, Wiren A. Lack of allergenic cross-reactivity between storage mites and Dermatophagoides pteronyssinus. Clin Allergy 1987;17(1):23-31



[ 12 ]

See: Storage mite, for overview

See also other Storage mites:
Glycyphagus domesticus (Storage mite)
Lepidoglyphus destructor (Storage mite)
Tyrophagus putrescens (storage mite)
Blomia kulagini (Storage mite)
Aleuroglyphus ovatus (Storage Mite)
Caloglyphus berlesei (Storage mite)
Blomia tjibodas (Storage mite)
Blomia freemani (Storage mite)
Acarus siro (storage mite)
Blomia tropicalis (Storage mite)

Reference:
Editor Comment Editorial comment, common knowledge, or still to add - -




Information supplied from an abridged section of:
Allergy Advisor - Zing Solutions
http://allergyadvisor.com/index.html

© zingsolutions.com 2014

Allergy Advisor  - Food Additive and Preservative Allergy and Intolerance Database


Close